Deatailed information for gene ENSG00000154639
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009781
- Gene Symbol: CXADR
- Ensembl ID: ENSG00000154639
-
Gene locus: chr21:17513129-17593579
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-15876479-15876649,
chr21-15891358-15891425,
chr21-15893413-15897253,
chr21-16933256-16933897,
chr21-16941592-16944786,
chr21-17051166-17051326,
chr21-17100049-17100447,
chr21-17105633-17106526,
chr21-17114019-17114504,
chr21-17119410-17120229,
chr21-17120454-17120726,
chr21-17376067-17376842,
chr21-17377529-17377890,
chr21-17383874-17384847,
chr21-17385065-17389738,
chr21-17390128-17390618,
chr21-17391038-17391864,
chr21-17392847-17393210,
chr21-17393972-17394584,
chr21-17402988-17403462,
chr21-17404236-17404703,
chr21-17418323-17418617,
chr21-17418933-17419226,
chr21-17421921-17422186,
chr21-17423187-17423402,
chr21-17427928-17429100,
chr21-17429707-17430271,
chr21-17433211-17433485,
chr21-17434658-17435287,
chr21-17436920-17439074,
chr21-17440398-17441901,
chr21-17442241-17442520,
chr21-17443841-17444029,
chr21-17444297-17444731,
chr21-17447844-17448535,
chr21-17508331-17509012,
chr21-17510239-17514988,
chr21-17515319-17515802,
chr21-17522555-17523601,
chr21-17523868-17524951,
chr21-17526082-17526410,
chr21-17527049-17527805,
chr21-17528207-17529568,
chr21-17534793-17535275,
chr21-17536516-17536792,
chr21-17537036-17537850,
chr21-17538088-17538316,
chr21-17538838-17539668,
chr21-17541078-17541535,
chr21-17542111-17543488,
chr21-17548224-17548770,
chr21-17549142-17551469,
chr21-17552603-17553088,
chr21-17553654-17556173,
chr21-17560450-17560648,
chr21-17564728-17565077,
chr21-17568081-17568434,
chr21-17573618-17573899,
chr21-17574945-17575093,
chr21-17575466-17576102,
chr21-17579296-17579640,
chr21-17581951-17582360,
chr21-17584154-17587049,
chr21-17592922-17593114,
chr21-17610934-17613664,
chr21-17650364-17650607,
chr21-17660473-17661158,
chr21-17661485-17661799,
chr21-17662469-17662816,
chr21-17668672-17669176,
chr21-17673220-17674924,
chr21-17801315-17801609,
chr21-17802147-17803028,
chr21-17804509-17804871,
chr21-17808054-17808570,
chr21-17817153-17820909,
chr21-17824544-17824781,
-
Co-expression with cohesin genes Rho = -0.0586
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.578
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.900
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MCF-10A,GM12892,K1,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,MCF-7,HEK293T,GM12891,SARS-Cov2-olfactory,GM12878,K-562,A-549,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,Primed-hESC,NCI-H1437,Liver,ARPE-19,HCT-116,OCI-AML-3,Hep-G2,HT-1197,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,GM19240,BMEC,SU-DHL-4,HUVEC,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Jurkat,HFF-hTERT,HAP1
- Related loop:
chr21:15875000-15900000~~chr21:17575000-17600000,
chr21:16925000-16950000~~chr21:17525000-17550000,
chr21:16925000-16950000~~chr21:17550000-17575000,
chr21:16925000-16950000~~chr21:17575000-17600000,
chr21:16942104-16943784~~chr21:17584882-17586850,
chr21:17050000-17075000~~chr21:17550000-17575000,
chr21:17100000-17125000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17500000-17525000,
chr21:17375000-17400000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17575000-17600000,
chr21:17385933-17388190~~chr21:17554000-17555508,
chr21:17385933-17388190~~chr21:17585378-17586847,
chr21:17385938-17388768~~chr21:17553974-17555843,
chr21:17385938-17388768~~chr21:17584830-17586831,
chr21:17385982-17388062~~chr21:17584894-17587061,
chr21:17385997-17387993~~chr21:17511653-17514907,
chr21:17385997-17387993~~chr21:17553561-17555852,
chr21:17385997-17387993~~chr21:17584718-17586899,
chr21:17386011-17388740~~chr21:17553679-17555816,
chr21:17386026-17387946~~chr21:17553932-17555551,
chr21:17386031-17388049~~chr21:17584682-17586783,
chr21:17386036-17388915~~chr21:17511577-17514929,
chr21:17386036-17388915~~chr21:17553843-17555843,
chr21:17386036-17388915~~chr21:17584766-17586992,
chr21:17386038-17389021~~chr21:17553442-17555850,
chr21:17386038-17389021~~chr21:17584614-17587020,
chr21:17386049-17388075~~chr21:17585127-17586877,
chr21:17386054-17389016~~chr21:17553561-17555841,
chr21:17386054-17389016~~chr21:17584615-17586797,
chr21:17386056-17387970~~chr21:17585070-17586716,
chr21:17386064-17388904~~chr21:17584829-17586982,
chr21:17386066-17388182~~chr21:17584650-17586844,
chr21:17386069-17388018~~chr21:17553849-17555556,
chr21:17386069-17388018~~chr21:17584882-17586850,
chr21:17386074-17388534~~chr21:17511356-17514781,
chr21:17386074-17388534~~chr21:17553871-17555826,
chr21:17386074-17388534~~chr21:17584717-17586949,
chr21:17386077-17388636~~chr21:17511764-17514939,
chr21:17386077-17388636~~chr21:17553840-17555851,
chr21:17386077-17388636~~chr21:17584710-17587013,
chr21:17386079-17388476~~chr21:17584668-17586918,
chr21:17386098-17389064~~chr21:17553871-17555565,
chr21:17386098-17389064~~chr21:17584658-17586849,
chr21:17386110-17389253~~chr21:17583722-17586723,
chr21:17386111-17388007~~chr21:17553874-17555626,
chr21:17386111-17388007~~chr21:17585385-17586756,
chr21:17386112-17388058~~chr21:17585381-17586741,
chr21:17386118-17388987~~chr21:17553707-17555628,
chr21:17386118-17388987~~chr21:17584710-17586759,
chr21:17386120-17388090~~chr21:17584777-17586913,
chr21:17386123-17388073~~chr21:17554074-17555851,
chr21:17386142-17388075~~chr21:17584963-17586801,
chr21:17386143-17388031~~chr21:17553907-17555596,
chr21:17386155-17388075~~chr21:17584973-17586950,
chr21:17386210-17388145~~chr21:17585190-17586791,
chr21:17386226-17388006~~chr21:17585307-17586805,
chr21:17386232-17388143~~chr21:17585338-17586757,
chr21:17386274-17388142~~chr21:17585346-17586763,
chr21:17386451-17388123~~chr21:17585377-17586812,
chr21:17386457-17388148~~chr21:17585337-17586760,
chr21:17386482-17388045~~chr21:17585364-17586763,
chr21:17386521-17388914~~chr21:17584891-17586781,
chr21:17386573-17387885~~chr21:17585423-17586769,
chr21:17386602-17387861~~chr21:17585457-17586613,
chr21:17400000-17425000~~chr21:17500000-17525000,
chr21:17400000-17425000~~chr21:17550000-17575000,
chr21:17400000-17425000~~chr21:17575000-17600000,
chr21:17425000-17450000~~chr21:17550000-17575000,
chr21:17500000-17525000~~chr21:27500000-27525000,
chr21:17511653-17514907~~chr21:17526487-17528802,
chr21:17550000-17575000~~chr21:17650000-17675000,
chr21:17575000-17600000~~chr21:17800000-17825000,
chr21:17597892-17599183~~chr21:17611016-17612344,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
GSE95015, GSE43070, 4DNFIDJ2JZ7Q, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR361AYD, 4DNFIZ4F74QR, 4DNFI7H4II2V, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFI9VXTBE2, 4DNFIRKGMZRQ, ENCSR668RDP, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, ENCSR499RVD, 4DNFIB7QTIMH, ENCSR146FPM, GSE69643, GSE155380, 4DNFIJWBWE41, ENCSR587DSF, ENCSR452NHL, GSE52457, 4DNFIBT4EAKN, Direct, ENCSR314HAC, 4DNFIXWCLD4M, 4DNFIH9U4I7I, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFIVJ3IIQL, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIZGCA8AH, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIE8E4ANZ, GSE120294, 4DNFIW8TIFI5, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, 4DNFIM2BMJ33, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, ENCSR404HWQ, 4DNFIFI6NIKJ, ENCSR933UZH, ENCSR094EIC, GSE58752, ENCSR507AHE, 4DNFI8649RQJ, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR866FWQ, 4DNFI6EIFUZI, GSE111537, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, 4DNFIOUSETUP, ENCSR752QCX, ENCSR128RPG, ENCSR312TUD, 4DNFI6JJQKFJ, GSE101921, 4DNFIOCW5AEM, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: HPC,OCI-AML-3,SLK,MCF-10A,U2OS,HeLa-S3,Keratinocytes,NUGC-3
- Cohesin-DEGs, number of studies: 16
- Cohesin-DEGs, study: GSE89799,GSE83870,GSE137253,GSE111537,GSE101921,GSE119828,GSE154086,GSE138937,GSE108869,GSE130558
- Cohesin-DEGs, subunit: SMC3,NIPBL,SA2,WAPL,CTCF,SMC1,Rad21,CdLS