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Basic information

CohesinDB ID: CDBG00009782

Gene Symbol: BTG3

Ensembl ID: ENSG00000154640

Gene locus: chr21:17593652-17612901 Strand: -

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-15601722-15602750, chr21-15603827-15604974, chr21-15605222-15605521, chr21-15606019-15606774, chr21-15610467-15610826, chr21-15614967-15615288, chr21-15616932-15619309, chr21-15620069-15620305, chr21-15620844-15621426, chr21-15726005-15726347, chr21-15726744-15727018, chr21-15728664-15733925, chr21-15734927-15736334, chr21-15737261-15737766, chr21-15741172-15745156, chr21-15748731-15750124, chr21-15876479-15876649, chr21-15891358-15891425, chr21-15893413-15897253, chr21-16549809-16552371, chr21-16553024-16553429, chr21-16554422-16555230, chr21-16555905-16556068, chr21-16556680-16557811, chr21-16561687-16562411, chr21-16563033-16564655, chr21-16565213-16565671, chr21-16569553-16572421, chr21-16572677-16573040, chr21-16573328-16574192, chr21-16574890-16574992, chr21-16933256-16933897, chr21-16941592-16944786, chr21-17376067-17376842, chr21-17377529-17377890, chr21-17383874-17384847, chr21-17385065-17389738, chr21-17390128-17390618, chr21-17391038-17391864, chr21-17392847-17393210, chr21-17393972-17394584, chr21-17402988-17403462, chr21-17404236-17404703, chr21-17418323-17418617, chr21-17418933-17419226, chr21-17421921-17422186, chr21-17423187-17423402, chr21-17592922-17593114, chr21-17599493-17599842, chr21-17600958-17601160, chr21-17602938-17603192, chr21-17610934-17613664, chr21-17615995-17616481, chr21-17801315-17801609, chr21-17802147-17803028, chr21-17804509-17804871, chr21-17808054-17808570, chr21-17817153-17820909, chr21-17824544-17824781, chr21-17900339-17904921, chr21-17905247-17905528, chr21-17907747-17907969, chr21-17911083-17912506, chr21-17921425-17922537, chr21-17923497-17927046,

Co-expression with cohesin genes Rho = 0.5523 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.378
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.875
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: MCF-7,OCI-AML-3,GM12878,HCT-116,SARS-Cov2-olfactory,Hep-G2,MCF-10A,A-549,HCC1599,Motor-Neuron,HAP1,HFFc6,MSLCL,H9-hESC,Olfactory

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: 4DNFIQWD8ZYD, ENCSR662QKG, GSE95015, ENCSR194SRI, 4DNFIMROE6N4, GSE108787, ENCSR794RDS, 4DNFI5SUHCGZ, ENCSR410MDC, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, GSE111537, 4DNFICSTCJQZ, ENCSR452NHL, 4DNFI9YAVTI1, 4DNFI3A3VYWU, Direct, 4DNFIX7H3CE2, 4DNFIV56OFE3, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, GSE116872, 4DNFIEJEFCAM, ENCSR393LOP, 4DNFIOCW5AEM, 4DNFI9ZWZ5BS, 4DNFIFLJLIS5, ENCSR094EIC, GSE105028, 4DNFII84FBKM

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: SLK,OCI-AML-3,P3HR-1,MCF-10A,CMK,HAP1,U2OS

Cohesin-DEGs, number of studies: 8

Cohesin-DEGs, study: GSE140651,GSE111537,GSE154086,GSE138937,GSE126635,GSE89799

Cohesin-DEGs, subunit: CTCF,SMC1,Rad21,SA2

eachgene

Deatailed information for gene ENSG00000154640