- Basic information
- CohesinDB ID: CDBP00415382
- Locus: chr21-26032239-26032891
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, ENCSR000BTU, GSE93080, GSE86191, GSE115250, GSE138405, GSE76893, GSE101921, GSE135093, GSE206145-NatGen2015, ENCSR703TNG, GSE116344, GSE94872, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR000EDE, GSE68388, GSE50893
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Cell type: RH4, GM10847, GM2610, GM19240, Liver, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, HeLa-S3, IMR-90, GM18486, GM18526, H1-hESC, SNYDER, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, HUVEC, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 14% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.644
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"4_Tx": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, FOXA2, MYCN, PAF1, SMAD3, FOXA1, SRF, CDK9, ZBTB2, ATF3, MYC, RAD21, HIF1A, PROX1, STAT3, MAX, FOS, SNAI2, SMAD1, STAG1, EZH2, ESR1, PKNOX1, USF2, CTCF, RBM22, MNT, GATA2, BRD4, SMC1, SMC3, ZNF554, PDX1
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 48
- Number of somatic mutations (non-coding): 0
- Related genes and loops