- Basic information
- CohesinDB ID: CDBP00415384
- Locus: chr21-26040358-26040769
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Data sourse: GSE132649, GSE206145-NatGen2015, GSE67783
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Cell type: T-47D, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 75%,
"15_Quies": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA1, NFIC, ZFP64, ZBTB44, ZNF189, ZNF121, PITX3, CTCF, TCF12, JUN, BAF155, EP300, TEAD4, PDX1, TFAP2C, GLIS1, POU2F2, CHD8, ZNF263, TOP2A, HOXC5, ASCL1, MYC, RAD21, NKX2-1, STAT3, RCOR1, ZNF639, CEBPB, EZH2, GRHL2, EBF3, SPI1, GATA2, SIX2, FLI1, MXI1, ZNF490, SMC1A, NKX2-2, SIN3A, POU4F2, ZNF770, TWIST1, ZNF35, RUNX2, GATA4, ZNF184, PBX4, DAXX, PBX3, MAFB, FOS, MED1, TEAD3, RBM22, MAFK, PHIP, FOXP1, SMC3, PPARG, FOXA2, CHD2, PAF1, JUNB, NEUROD1, TCF4, HIF1A, OTX2, GATA3, MAX, GATA1, HAND2, SP7, NEUROG2, PKNOX1, ZNF334, NFKB1, MYOD1, PHOX2B, AR, ZBTB42, BRD4, JUND, FOSL2
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops