Deatailed information for cohesin site CDBP00415389


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00415389
  • Locus: chr21-26057470-26057741
  • Data sourse: GSE206145, GSE116344, ENCSR917QNE
  • Cell type: Liver, RH4, HEK293T
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 68% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "5_TxWk": 59%, "15_Quies": 19%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, PGR, XBP1, PATZ1, FOXA1, ZNF90, NFIC, ZNF362, ZBTB44, ZNF189, SFPQ, ZNF629, TEAD1, TRIM28, ZNF121, ESR1, TP73, CTCF, ZNF577, TCF12, GATA6, PDX1, TFAP2C, GLIS1, ZNF263, POU5F1, ZSCAN21, ZBTB48, HOXC5, USP7, MYC, SMARCA4, STAT3, XRCC5, NFE2, NR2F6, ZNF639, VDR, NR3C1, ESRRA, GRHL2, FEZF1, TRPS1, SPI1, GATA2, SIX2, ZNF766, ZIM3, RUNX1, CEBPA, LDB1, SIN3A, ZFX, SMAD3, ZNF770, ERG3, PRDM10, ZBTB2, ZNF384, RUNX2, GATA4, OSR2, ARNT, PBX3, MAFB, MED1, TEAD3, ZXDB, ZNF22, RBM22, HNF4A, PHIP, PRDM6, ZNF34, ZNF394, FOXA2, EBF1, PAF1, ZNF692, GTF2B, KDM1A, YY1, RELA, ZIC2, OTX2, GATA3, TAL1, MAX, ZNF449, GATA1, AGO2, BCL11B, SP7, GFI1B, NR2F2, MYOD1, BRD2, ZNF843, ELF3, AR, ZBTB42, ZNF366, BRD4, AHR
  • Target gene symbol (double-evidenced CRMs): APP,CYYR1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 16
  • Number of somatic mutations (non-coding): 2
  • Related genes and loops

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