Deatailed information for cohesin site CDBP00415396

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  • Basic information
  • CohesinDB ID: CDBP00415396
  • Locus: chr21-26072693-26073278
  • Data sourse: ENCSR000EFJ, ENCSR000EHX, ENCSR000BLY, GSE165895
  • Cell type: IMR-90, SK-N-SH, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: Rad21,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 68% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 41%, "7_Enh": 33%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, SMARCA2, ZSCAN5C, SOX2, XBP1, FOXA1, ZNF90, ATF3, ZFP64, ZNF362, ZBTB44, PRDM1, IKZF3, ZNF322, CHD7, ZNF189, PAX5, ZNF736, MAF, ELF1, TRIM28, BCLAF1, TEAD1, ESR1, OCA2, TP73, PITX3, USF2, ZNF561, JUN, SND1, CTCF, BAF155, TCF12, EP300, MNT, GATA6, DPF2, E2F6, RAD51, ZNF528, TEAD4, PDX1, RBPJ, TFAP2C, EED, GLIS1, NANOG, CHD8, POU2F2, ZNF263, POU5F1, TOP2A, ZNF778, BRD3, MTA2, ZBTB17, DUX4, ZSCAN21, STAT1, ZNF317, ZBTB48, SRF, NBN, ERG2, SP4, HNF4G, ERG, PAX6, HOXC5, PBX1, MYC, ONECUT1, SMARCA4, EOMES, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, IKZF1, RCOR1, NR3C1, ESRRA, CEBPB, KMT2A, KLF8, FEZF1, GRHL2, EBF3, ZHX2, SPI1, GATA2, FLI1, MXI1, RELB, MRTFB, ZIM3, ETV5, RUNX1, BCL6, NKX2-2, SIN3A, ZFX, POU4F2, ERG3, TWIST1, ZNF18, SMARCC1, CREBBP, ZNF35, NOTCH1, ZNF384, RUNX2, CDK6, GATA4, OSR2, ARNT, PBX4, DAXX, ZEB2, ZNF518A, PBX3, MAFB, FOS, CDK8, MED1, ZEB1, TEAD3, ZXDB, MYB, KLF9, RBM22, MAFK, BCL11A, SP1, USF1, HNF4A, REST, ZBTB7A, ATF7, POU2F3, ASH2L, PHIP, TCF3, FOXP1, PRDM6, ELL2, NCOR2, ZNF34, MLLT1, ZNF394, PPARG, FOXA2, MEIS1, PAF1, ZNF600, ZSCAN16, ZNF692, GTF2B, ZBTB33, HOXB13, KDM1A, YY1, RELA, TARDBP, JUNB, ISL1, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, GATA1, ZNF143, HAND2, ZFP69B, KLF4, SP7, NCOA3, NR2F2, TP53, PKNOX1, MED, ZNF334, ZSCAN22, EGR2, PHOX2B, T, BRD2, ELF3, TBX21, ZNF12, AR, PAX3-FOXO1, BHLHE40, ZNF366, IKZF2, JUND, BRD4, NOTCH3, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): APP,CYYR1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 16
  • Number of somatic mutations (non-coding): 2
  • Related genes and loops
  • Related gene: ENSG00000142192, ENSG00000166265,
  • Related loop: chr21:25600000-25625000~~chr21:26075000-26100000, chr21:25875000-25900000~~chr21:26050000-26075000, chr21:25950000-25975000~~chr21:26050000-26075000, chr21:25950000-25975000~~chr21:26075000-26100000, chr21:26050000-26075000~~chr21:26150000-26175000, chr21:26050000-26075000~~chr21:26375000-26400000, chr21:26050000-26075000~~chr21:26525000-26550000, chr21:26075000-26100000~~chr21:26700000-26725000, chr21:26075000-26100000~~chr21:28425000-28450000,
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