- Basic information
- CohesinDB ID: CDBP00415397
- Locus: chr21-26076786-26077083
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Data sourse: GSE206145, GSE86191
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Cell type: RPE, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"15_Quies": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, FOXO1, NKX2-2, TOP2A, SOX2, ZFX, XBP1, ZBTB17, ZBTB48, SMAD3, FOXA1, ERG3, HOXB13, ZNF384, ASCL1, NEUROD1, MYC, RUNX2, SMARCA4, ZBTB44, RAD21, PRDM1, ARNT, OTX2, ATF2, STAT3, MAX, PBX3, HAND2, MYOG, ZEB1, ELF1, ETV1, NEUROG2, EZH2, LMO2, ZIM3, PITX3, TBX5, MYOD1, ZNF22, CTCF, RBM22, NUP98-HOXA9, SPI1, PHOX2B, MAFK, TCF12, AR, GATA2, SIX2, FLI1, BRD4, PHIP, JUND, PRDM6, MRTFB, TEAD4, PDX1, FOSL2
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
- Related loop:
chr21:25600000-25625000~~chr21:26075000-26100000,
chr21:25875000-25900000~~chr21:26050000-26075000,
chr21:25950000-25975000~~chr21:26050000-26075000,
chr21:25950000-25975000~~chr21:26075000-26100000,
chr21:26050000-26075000~~chr21:26150000-26175000,
chr21:26050000-26075000~~chr21:26375000-26400000,
chr21:26050000-26075000~~chr21:26525000-26550000,
chr21:26075000-26100000~~chr21:26700000-26725000,
chr21:26075000-26100000~~chr21:28425000-28450000,