- Basic information
- CohesinDB ID: CDBP00415401
- Locus: chr21-26084181-26084592
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE111913, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, RT-112
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 66%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, FOXA2, SMAD3, ZBTB48, WT1, FOXA1, TET2, ERG3, ZNF823, ERG2, HOXB13, BCL3, ERG, MEF2A, RELA, YY1, ZNF384, OGG1, ETS1, ONECUT1, NFIC, SMARCA4, ZNF362, RAD21, CHD7, ZBTB44, SP140, ZNF487, GATA3, TAL1, CDK8, MED1, NR3C1, ZEB1, ELF1, ETV1, PIAS1, EGR2, ZNF22, BRD2, RBM22, T, SPI1, NUP98-HOXA9, JUN, TBX21, ZHX2, GATA6, IRF1, GATA2, E2F6, SIX2, POU2F3, FLI1, HOXA9, PHIP, PRDM6, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops