- Basic information
- CohesinDB ID: CDBP00415408
- Locus: chr21-26101093-26101372
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 71%,
"15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SMARCA2, ZNF660, ZSCAN5C, SOX2, PATZ1, FOXA1, RBFOX2, PBX2, ATF3, BMI1, ZFP64, ZNF362, ZBTB44, CHD7, IKZF3, PRDM1, ATF4, TP63, INTS11, TEAD1, TRIM28, E2F5, ZNF573, ESR1, PITX3, ZNF561, CTCF, JUN, EP300, ZNF695, ZBTB20, GATA6, E2F6, TRIM24, E2F4, DDX20, E2F1, ZNF280A, TEAD4, KMT2B, ZNF175, PDX1, TFAP2C, NANOG, CHD8, POU2F2, POU5F1, MYCN, CTBP1, ZSCAN21, ZBTB17, ZBTB48, DUX4, STAT1, ZNF205, ERG, OGG1, ONECUT1, MYC, SMARCA4, EOMES, LHX2, GRHL3, NKX2-1, STAT3, NKX3-1, IKZF1, RCOR1, NFE2, NFRKB, ZNF750, CEBPB, ZNF93, KMT2A, GRHL2, FEZF1, TRPS1, SPI1, ZNF664, GATA2, ZNF644, FLI1, EP400, MRTFB, ZNF554, ATF1, GTF2A2, ZNF585A, CBX1, CEBPA, NKX2-2, HDAC1, EZH2phosphoT487, AFF4, ZFX, ZNF534, SMAD3, ZBTB12, ERG3, SMARCC1, PRDM10, ZNF549, ZNF384, ZNF35, ZSCAN30, GATA4, OSR2, PBX4, ARNT, TFDP1, BACH1, HMBOX1, ZEB2, ZNF518A, FOS, CDK8, ZNF584, MYB, PIAS1, L3MBTL2, RBM22, BCL11A, REST, POU2F3, ZHX1, HOXA9, CTBP2, PHIP, PRDM6, ELL2, ZNF34, MLLT1, ZNF394, FOXA2, RBBP5, PAF1, ZSCAN16, ZNF692, FOXF1, ZNF574, ZBTB33, HOXB13, ZNF318, KDM1A, ZNF589, RELA, YY1, JUNB, NEUROD1, ISL1, SP140, ZFP36, HIF1A, OTX2, GATA3, ZNF519, MGA, MAX, ZNF143, HAND2, KLF4, CEBPG, SP7, ZFP69B, ZKSCAN8, ZNF83, PHOX2B, T, BHLHE40, AR, ZBTB40, ZNF366, RNF2, BRD4, JUND, ZNF440, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops