- Basic information
- CohesinDB ID: CDBP00415413
- Locus: chr21-26122436-26122650
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Data sourse: ENCSR000BLD, ENCSR000ECE
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Cell type: H1-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 57%,
"15_Quies": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, HMG20A, ZNF660, ZSCAN5C, SOX2, XBP1, PATZ1, FOXA1, RXRB, TFAP4, ATF3, ZFP64, ZNF362, ZBTB44, PRDM1, IKZF3, CHD7, ZNF189, TP63, MZF1, HDAC3, ZNF467, ZNF629, MAF, MYOG, TEAD1, TRIM28, ZNF573, ETV1, KLF5, ZNF557, KLF10, ESR1, TP73, PITX3, USF2, CTCF, TCF12, JUN, BAF155, EP300, ZNF695, ZBTB20, GATA6, SOX5, PAX8, PRDM4, IRF4, E2F4, ZNF528, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, TFAP2C, EED, RBPJ, GLIS1, NANOG, CHD8, BRD1, ZNF425, ZNF263, POU5F1, ZNF778, MYCN, BRD3, POU2F2, ZSCAN21, ZBTB17, ZBTB48, ZNF317, TOP2A, MLLT3, DDX5, SAP130, HNF4G, ERG, USP7, ETS1, MYC, EOMES, SMARCA4, HOMEZ, RAD21, LHX2, GRHL3, FOXP2, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, RCOR1, MIER3, ARNTL, VDR, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, ZBTB11, EZH2, KLF8, FEZF1, GRHL2, EBF3, TRPS1, GABPB1, ZHX2, EHF, IRF1, HDAC2, GATA2, ZNF644, GATAD2B, SIX2, FLI1, MXI1, NFIL3, ZIM3, RUNX1, BCL6, CEBPA, NKX2-2, SIN3A, AFF4, POU4F2, ZFX, SOX13, SMAD3, ERG3, ZNF18, PRDM10, TWIST1, CREBBP, ZNF384, ZNF35, RARA, RUNX2, GATA4, OSR2, ZNF184, GR, ARNT, PBX4, HMGB2, ZEB2, SMAD4, PBX3, MAFB, ZNF10, FOS, HMGXB4, MED1, ZEB1, TEAD3, CEBPD, ZXDB, SCRT2, PIAS1, ZNF680, SETDB1, TBX5, RBM22, MAFK, SP1, USF1, HNF4A, IKZF5, REST, ZNF479, ARID1A, ASH2L, HOXA9, CTBP2, PHIP, FOXP1, PRDM6, SMC3, ZNF34, HMGB1, MLLT1, ZNF394, PPARG, FOXA2, ZNF316, CHD2, PAF1, ZNF600, ZNF692, ZSCAN16, MAFF, ZNF30, WT1, FOXF1, CDK9, HOXB13, KDM1A, YY1, RELA, JUNB, NEUROD1, BRCA1, ZIC2, HIF1A, TCF4, OTX2, GATA3, TAL1, MAX, NRIP1, GATA1, ZNF143, HAND2, TLE3, KLF4, BCL11B, SP7, GFI1B, NR2F2, NCOA3, TCF7L2, TP53, PKNOX1, ZNF334, BCL6B, MYOD1, ZSCAN22, PHOX2B, BRD2, ZNF843, ELF3, ARRB1, BHLHE40, AR, ZNF366, ZBTB42, ZBTB26, NCOR1, NOTCH3, BRD4, JUND, CLOCK, MAZ, ZSCAN23, TBX2, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops