- Basic information
- CohesinDB ID: CDBP00415418
- Locus: chr21-26138612-26139133
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Data sourse: GSE206145-GSE177045, ENCSR676MJK, ENCSR230ZWH
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Cell type: MCF-7, Liver, A-549
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 63%,
"15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX5, PGR, HMG20A, ZSCAN5C, PATZ1, FOXA1, PBX2, ZFHX2, BMI1, NFIC, ATF3, ZNF362, RUNX3, PRDM1, ZBTB44, ATF4, CBFB, ZNF273, MECOM, ZNF189, PAX5, MZF1, HDAC3, MAF, ZNF629, TEAD1, BCLAF1, TRIM28, ELF1, KLF6, KLF10, ESR1, ZNF561, JUN, TCF12, BAF155, EP300, ZNF695, ZBTB20, KLF1, SOX5, DPF2, PRDM4, IRF4, TRIM24, RFX5, FOXA3, ZNF175, GATAD2A, RBPJ, EED, POU2F2, POU5F1, MTA2, ZBTB17, ZBTB48, ZSCAN21, ZNF317, DDX5, ERG2, HNF4G, ERG, CHD4, ZNF341, ONECUT1, MYC, HOMEZ, RAD21, RXRA, GABPA, STAT3, NKX3-1, IKZF1, NR3C1, CEBPB, KMT2A, ZBTB11, EZH2, KLF8, FEZF1, ZKSCAN5, SPI1, HDAC2, GATA2, FLI1, SMARCA5, NFIL3, RUNX1, THAP11, BCL6, CEBPA, ZNF707, SOX13, ZFX, REPIN1, ZNF770, TRIM22, ZNF18, PRDM10, MEF2A, ZBTB2, RARA, ZNF35, OSR2, ZNF184, ARNT, BACH1, PBX4, DAXX, ATF2, ZEB2, ETV6, PBX3, FOXM1, FOS, CDK8, MED1, TERF1, CEBPD, ZNF558, PIAS1, EVI1, RBM22, BCL11A, SP1, NR4A1, HNF4A, ARID1A, ATF7, ASH2L, PHIP, FOXP1, PRDM6, ZNF34, MLLT1, NFATC3, MEF2B, FOXA2, CREM, MEIS1, PAF1, ZNF692, ZBED1, WT1, ZSCAN16, ZNF574, CDK9, HOXB13, ZNF580, KDM1A, YY1, JUNB, NEUROD1, BRG1, ZNF610, SKIL, HIF1A, OTX2, GATA3, BATF, TLE3, KLF4, CEBPG, SP7, ZFP69B, PKNOX1, ZNF213, NFKB1, BCL6B, ELF3, BRD2, ZNF843, TBX21, BHLHE40, AR, ARID4B, ZBTB40, ZNF324, ZNF366, IKZF2, BRD4, JUND, MAZ, ZSCAN23, IRF9, ZNF24, FOSL2
- Target gene symbol (double-evidenced CRMs): APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops