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Basic information

CohesinDB ID: CDBP00415428

Locus: chr21-26159924-26160609

Data sourse: GSE62063, ENCSR230ZWH, ENCSR000BLY

Cell type: Liver, SK-N-SH, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 51%, "15_Quies": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, PGR, FOXA2, NKX2-2, CEBPA, TOP2A, PAF1, ZNF317, FOXA1, RBFOX2, ERG, YY1, RELA, ZNF384, NOTCH1, NEUROD1, MYC, NFIC, RAD21, PBX4, HIF1A, RXRA, OTX2, GATA3, ZNF189, MAX, ZNF143, GATA1, NFE2, KMT2A, SNAI2, PIAS1, ESR1, ZNF334, NFKB1, PHOX2B, ELF3, SP1, BCL11A, SPI1, HNF4A, AR, REST, GATA2, EGLN2, ZBTB42, PHIP, PRDM6, PDX1

Target gene symbol (double-evidenced CRMs): GABPA,CYYR1,ADAMTS1,MRPL39,JAM2,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 7

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154727, ENSG00000142192, ENSG00000166265, ENSG00000154734,

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Deatailed information for cohesin site CDBP00415428