- Basic information
- CohesinDB ID: CDBP00415441
- Locus: chr21-26192241-26192738
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Data sourse: GSE206145-NatGen2015, GSE67783
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Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 90%,
"14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, ZFX, RAD51, ZBTB17, WT1, HIF1A, GRHL3, USF2, ZNF677, CTCF, MITF
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
- Related loop:
chr21:25575000-25600000~~chr21:26175000-26200000,
chr21:25600000-25625000~~chr21:26175000-26200000,
chr21:25850000-25875000~~chr21:26175000-26200000,
chr21:25875000-25900000~~chr21:26175000-26200000,
chr21:26175000-26200000~~chr21:26375000-26400000,
chr21:26175000-26200000~~chr21:26675000-26700000,
chr21:26175000-26200000~~chr21:26700000-26725000,
chr21:26175000-26200000~~chr21:27500000-27525000,
chr21:26175000-26200000~~chr21:28725000-28750000,
chr21:26175000-26200000~~chr21:29075000-29100000,