- Basic information
- CohesinDB ID: CDBP00415463
- Locus: chr21-26280655-26281366
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE97394, GSE115248, ENCSR000BLY, ENCSR000EHW, GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR000EHX, GSE68388, GSE83726, GSE116344, GSE25021, ENCSR000ECS
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, RH4, Ishikawa, Kelly, HeLa-S3, HUES64, SK-N-SH, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 69%,
"7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, FOXA1, ZNF362, CHD7, ZNF189, MYOG, TRIM28, ESR1, PITX3, CTCF, TCF12, EP300, TEAD4, GLIS1, NANOG, CHD8, MYCN, POU5F1, BRD3, ZNF263, ZBTB17, ZBTB48, DUX4, SRF, DDX5, TBP, ERG, ASCL1, MYC, SMARCA4, RAD21, GRHL3, RCOR1, NR3C1, EZH2, EBF3, GATA2, SIX2, FLI1, ZNF777, MXI1, MRTFB, EZH2phosphoT487, ZNF335, POU4F2, ZNF654, NMYC, SMARCC1, PRDM10, TWIST1, ZNF549, ZNF384, OSR2, ARNT, PBX3, MED1, SCRT2, KLF9, SETDB1, REST, SMC3, CHD2, SS18, ZNF692, HOXB13, KDM1A, RELA, NEUROD1, ISL1, ZIC2, TCF4, HIF1A, OTX2, GATA3, MAX, ZNF143, HAND2, NEUROG2, PKNOX1, ZSCAN22, MYOD1, PHOX2B, AR, MAML3, ZBTB42, MYNN, BRD4, SCRT1, TBX2
- Target gene symbol (double-evidenced CRMs): CYYR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops