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Basic information

CohesinDB ID: CDBP00415480

Locus: chr21-26375270-26375569

Data sourse: GSE206145

Cell type: RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 54% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 92%, "7_Enh": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMC1A, ZNF316, FOXA2, POU5F1, SS18, DUX4, SMAD3, MAFF, BAHD1, HOXC5, JUNB, AHR, SMARCA4, DAXX, PBX4, GRHL3, NKX2-1, PRDM9, TAL1, STAT3, MAX, SOX10, ZNF143, FOS, TP63, KLF4, ZNF750, ZFP69B, TEAD1, ZNF573, NFE2L2, TP53, OCA2, ZNF334, NFKB1, ELF3, CTCF, JUN, MAFK, ZNF786, IRF4, FLI1, BRD4, TFAP2C, FOSL2

Target gene symbol (double-evidenced CRMs): GABPA,APP,MRPL39,CYYR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154727, ENSG00000142192, ENSG00000166265,

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Deatailed information for cohesin site CDBP00415480