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Basic information

CohesinDB ID: CDBP00415482

Locus: chr21-26385630-26386225

Data sourse: GSE103477, GSE206145-NatGen2015, GSE206145

Cell type: RPE, Fibroblast, THP-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 54% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 79%, "7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SKI, FOSL1, CEBPA, ZFX, SMAD3, FOXA1, MLLT3, MEF2C, CDK9, KDM1A, ERG, RELA, HOXC5, LYL1, JUNB, MYC, RAD21, PBX4, GATA3, BATF3, STAT3, MAX, FOS, GFI1, CDK8, RCOR1, NFE2, MED1, VDR, NR3C1, CEBPB, JMJD1C, ESRRA, TEAD1, TRIM28, MYB, KMT2A, TCF7L2, ZNF680, KDM5B, LMO2, ESR1, MLL, GRHL2, SETDB1, STAT5A, JUN, TCF12, SPI1, EP300, EHF, TRIM24, FLI1, BRD4, KMT2B, MLLT1

Target gene symbol (double-evidenced CRMs): CYYR1,MRPL39,GABPA,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154727, ENSG00000142192, ENSG00000166265,

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Deatailed information for cohesin site CDBP00415482