- Basic information
- CohesinDB ID: CDBP00415488
- Locus: chr21-26412621-26413492
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Data sourse: ENCSR000BLD, GSE98367, GSE126634, ENCSR404BPV, GSE152721, GSE120943
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Cell type: H1-hESC, Monocytes, Neurons-H1, HAP1, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 88%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, REST, ETS1, FOXA2, EZH2phosphoT487, CHD8, ETV1, SOX2, T, CHD7, RAD21, OTX2, FOXA1, DDX5, MAX, ZSCAN4, ERG, YY1
- Target gene symbol (double-evidenced CRMs): APP,GABPA
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops