- Basic information
- CohesinDB ID: CDBP00415495
- Locus: chr21-26447728-26450082
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Data sourse: GSE101921, GSE206145-NatGen2015
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Cell type: HMEC, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 62%,
"7_Enh": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, CHD8, SMC1A, PPARG, POU5F1, EZH2phosphoT487, SOX2, SIN3A, XBP1, FOXA1, SRF, HOXB13, RELA, NEUROD1, ATF3, ZNF25, MYC, RUNX2, SMARCA4, CHD7, PRDM1, ARNT, ATF2, STAT3, MAX, TP63, NKX3-1, MED1, TLE3, NR3C1, CEBPB, TEAD1, NR2F2, CREB1, ETV1, OCA2, NFKB1, MYOD1, TBX5, JUN, MAFK, SPI1, SP1, AR, FLI1, BRD4, MRTFB, TEAD4, NCOR2, STAG2
- Target gene symbol (double-evidenced CRMs): CYYR1,APP,GABPA
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25750000-25775000~~chr21:26450000-26475000,
chr21:25825000-25850000~~chr21:26450000-26475000,
chr21:25850000-25875000~~chr21:26450000-26475000,
chr21:26150000-26175000~~chr21:26425000-26450000,
chr21:26225000-26250000~~chr21:26450000-26475000,
chr21:26425000-26450000~~chr21:26525000-26550000,
chr21:26425000-26450000~~chr21:26550000-26575000,
chr21:26450000-26475000~~chr21:26625000-26650000,