Deatailed information for gene ENSG00000141956
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00008177
- Gene Symbol: PRDM15
- Ensembl ID: ENSG00000141956
-
Gene locus: chr21:41798224-41879473
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-41149841-41150938,
chr21-41151775-41151894,
chr21-41153773-41154330,
chr21-41159227-41159964,
chr21-41165212-41165810,
chr21-41166931-41172082,
chr21-41173473-41173655,
chr21-41177726-41178272,
chr21-41179066-41179600,
chr21-41186135-41187378,
chr21-41196787-41197468,
chr21-41199133-41199869,
chr21-41200720-41201085,
chr21-41203279-41204508,
chr21-41207311-41209537,
chr21-41213457-41213771,
chr21-41214800-41215219,
chr21-41216467-41217270,
chr21-41217596-41218016,
chr21-41218863-41219208,
chr21-41219451-41220069,
chr21-41221113-41223031,
chr21-41223341-41223563,
chr21-41224862-41225153,
chr21-41279309-41286918,
chr21-41287349-41287624,
chr21-41289470-41289790,
chr21-41290198-41290717,
chr21-41291671-41292309,
chr21-41295717-41296311,
chr21-41303650-41304823,
chr21-41310090-41310814,
chr21-41312700-41313050,
chr21-41315579-41317852,
chr21-41318233-41318586,
chr21-41319164-41319889,
chr21-41320310-41323824,
chr21-41349571-41350286,
chr21-41350528-41350953,
chr21-41351402-41351758,
chr21-41351961-41352359,
chr21-41355172-41355403,
chr21-41356031-41356141,
chr21-41357146-41357972,
chr21-41358175-41363229,
chr21-41363511-41364777,
chr21-41365610-41366077,
chr21-41366312-41368581,
chr21-41368785-41370859,
chr21-41373113-41380866,
chr21-41442477-41454571,
chr21-41454845-41457031,
chr21-41457310-41463776,
chr21-41465279-41466074,
chr21-41466276-41469670,
chr21-41470417-41471816,
chr21-41472869-41473818,
chr21-41474341-41474869,
chr21-41499971-41502531,
chr21-41504215-41505004,
chr21-41505347-41509529,
chr21-41509897-41510115,
chr21-41510454-41511185,
chr21-41511910-41512243,
chr21-41512550-41513397,
chr21-41518109-41518579,
chr21-41520133-41522085,
chr21-41523158-41523411,
chr21-41524547-41525042,
chr21-41600668-41607029,
chr21-41607264-41617134,
chr21-41617741-41618159,
chr21-41619036-41619135,
chr21-41620001-41623327,
chr21-41625452-41626403,
chr21-41627233-41628368,
chr21-41629667-41633608,
chr21-41634030-41636192,
chr21-41636682-41637531,
chr21-41638110-41638628,
chr21-41639388-41640365,
chr21-41640676-41643854,
chr21-41645785-41646060,
chr21-41647714-41649300,
chr21-41649662-41650037,
chr21-41725384-41728963,
chr21-41729720-41730717,
chr21-41733728-41735705,
chr21-41736150-41737391,
chr21-41737818-41738231,
chr21-41740057-41742738,
chr21-41743343-41747580,
chr21-41748428-41748917,
chr21-41749162-41749630,
chr21-41750044-41752982,
chr21-41753429-41753815,
chr21-41754380-41755068,
chr21-41755301-41757502,
chr21-41758041-41771900,
chr21-41772125-41773546,
chr21-41774945-41781439,
chr21-41793143-41793460,
chr21-41794325-41795136,
chr21-41796584-41797209,
chr21-41797596-41797844,
chr21-41798299-41798682,
chr21-41799784-41800050,
chr21-41800258-41800436,
chr21-41800941-41801669,
chr21-41801918-41803799,
chr21-41804360-41804854,
chr21-41805059-41805238,
chr21-41805853-41806997,
chr21-41807830-41808572,
chr21-41808928-41810866,
chr21-41811647-41812381,
chr21-41812630-41814016,
chr21-41814372-41823630,
chr21-41823944-41825655,
chr21-41827924-41829367,
chr21-41830742-41836906,
chr21-41837774-41838052,
chr21-41838738-41839946,
chr21-41842489-41843082,
chr21-41844161-41847949,
chr21-41849107-41849386,
chr21-41850983-41851877,
chr21-41852110-41853345,
chr21-41853692-41855866,
chr21-41857229-41860002,
chr21-41861355-41866024,
chr21-41866387-41867228,
chr21-41867863-41869049,
chr21-41871292-41871941,
chr21-41872703-41874138,
chr21-41874717-41875401,
chr21-41876290-41881136,
chr21-41882621-41883088,
chr21-41883793-41886940,
chr21-41894414-41896406,
chr21-41896799-41898324,
chr21-41916566-41919291,
chr21-41925348-41930095,
chr21-41930445-41934884,
chr21-41935426-41935789,
chr21-41936840-41937153,
chr21-41939422-41940001,
chr21-41942461-41944496,
chr21-41947046-41947327,
chr21-41947715-41949276,
chr21-41950243-41951395,
chr21-41951919-41960803,
chr21-41961161-41962054,
chr21-41962297-41963236,
chr21-41964196-41969097,
chr21-41970716-41971987,
chr21-41972592-41976832,
chr21-41977344-41977846,
chr21-41982603-41983049,
chr21-41985616-41986038,
chr21-41991035-41991464,
chr21-41992633-41992921,
chr21-41993548-41994398,
chr21-41995205-41996303,
chr21-42001760-42004907,
chr21-42005507-42006937,
chr21-42007533-42014157,
chr21-42016245-42016751,
chr21-42017482-42017833,
chr21-42018954-42023204,
chr21-42024136-42028162,
chr21-42047213-42050893,
chr21-42051580-42052235,
chr21-42053659-42066910,
chr21-42067521-42069314,
chr21-42069730-42069902,
chr21-42071020-42072208,
chr21-42072432-42077357,
chr21-42077774-42087507,
chr21-42088172-42088785,
chr21-42089069-42090481,
chr21-42091730-42092368,
chr21-42092772-42095377,
chr21-42096641-42096982,
chr21-42097185-42102518,
chr21-42102731-42103045,
chr21-42103416-42126825,
chr21-42227795-42229175,
chr21-42230678-42231156,
chr21-42231900-42241298,
chr21-42242225-42243536,
chr21-42243826-42244231,
chr21-42244704-42245167,
chr21-42245409-42246173,
chr21-42247763-42247993,
chr21-42248295-42251114,
chr21-42272186-42275483,
chr21-42275794-42277332,
chr21-42278585-42283213,
chr21-42283471-42284076,
chr21-42284283-42285457,
chr21-42285916-42288654,
chr21-42289750-42290327,
chr21-42290743-42296744,
chr21-42298296-42298540,
chr21-42299343-42300483,
chr21-42422915-42428748,
chr21-42429069-42429373,
chr21-42429892-42431565,
chr21-42432008-42432290,
chr21-42433805-42434474,
chr21-42434904-42435230,
chr21-42436840-42441137,
chr21-42442018-42442307,
chr21-42443007-42454584,
chr21-42473712-42475050,
chr21-42475275-42477409,
chr21-42478322-42479169,
chr21-42480568-42481138,
chr21-42482081-42482692,
chr21-42485826-42486174,
chr21-42486445-42487207,
chr21-42488988-42489705,
chr21-42494711-42497356,
chr21-42499096-42500557,
chr21-42501424-42501674,
chr21-42502080-42502217,
chr21-42502708-42504189,
chr21-42504444-42505658,
chr21-42508152-42508427,
chr21-42509210-42509582,
chr21-42512399-42517747,
chr21-42517993-42518929,
chr21-42520617-42521491,
chr21-42521907-42522162,
chr21-42522739-42523588,
chr21-42524067-42525788,
chr21-42799515-42801184,
chr21-42801570-42802027,
chr21-42804198-42804619,
chr21-42806323-42807117,
chr21-42807469-42808220,
chr21-42809607-42810029,
chr21-42810534-42811625,
chr21-42812043-42812143,
chr21-42812479-42812787,
chr21-42815294-42815581,
chr21-42816699-42821466,
-
Co-expression with cohesin genes Rho = 0.5165
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.293
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.857
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,GM12892,K1,hTERT-HME1,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,MSiPS,K-562,Naive-hESC,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,SU-DHL-2,H9-hESC,KU-19-19,Primed-hESC,NCI-H1437,Liver,REC-1,ARPE-19,HCT-116,Germinal-Center-B,OCI-AML-3,Hep-G2,HT-1197,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,HUES64,SU-DHL-4,CyT49-hESC,HUVEC,HL-60,NPC-H9,RT-112,Skin-Fibroblast,Left-Ventricle,CyT49-Gut,CC-2551,HAP1,HFF-hTERT,MCF7-FASR,U251
- Related loop:
chr21:41150000-41175000~~chr21:41775000-41800000,
chr21:41175000-41200000~~chr21:41775000-41800000,
chr21:41200000-41225000~~chr21:41825000-41850000,
chr21:41275000-41300000~~chr21:41775000-41800000,
chr21:41275000-41300000~~chr21:41800000-41825000,
chr21:41275000-41300000~~chr21:41825000-41850000,
chr21:41281909-41284412~~chr21:41816016-41818176,
chr21:41282093-41284330~~chr21:41815923-41818297,
chr21:41282193-41284644~~chr21:41815835-41818294,
chr21:41282205-41284637~~chr21:41815737-41818351,
chr21:41282224-41284707~~chr21:41815737-41818316,
chr21:41282271-41284327~~chr21:41815837-41818350,
chr21:41282272-41284702~~chr21:41815747-41818270,
chr21:41282441-41284676~~chr21:41815802-41818289,
chr21:41282503-41284621~~chr21:41815822-41818125,
chr21:41282688-41284172~~chr21:41816062-41818083,
chr21:41300000-41325000~~chr21:41775000-41800000,
chr21:41300000-41325000~~chr21:41800000-41825000,
chr21:41300000-41325000~~chr21:41825000-41850000,
chr21:41350000-41375000~~chr21:41850000-41875000,
chr21:41450000-41475000~~chr21:41825000-41850000,
chr21:41500000-41525000~~chr21:41775000-41800000,
chr21:41600000-41625000~~chr21:41775000-41800000,
chr21:41600000-41625000~~chr21:41800000-41825000,
chr21:41600000-41625000~~chr21:41825000-41850000,
chr21:41600000-41625000~~chr21:41850000-41875000,
chr21:41609719-41611366~~chr21:41815837-41818350,
chr21:41609762-41611341~~chr21:41815868-41818188,
chr21:41609802-41611271~~chr21:41815835-41818259,
chr21:41609846-41611318~~chr21:41815737-41818351,
chr21:41609880-41611334~~chr21:41815828-41818342,
chr21:41609888-41611281~~chr21:41815812-41818317,
chr21:41609918-41611406~~chr21:41815864-41818241,
chr21:41609924-41613852~~chr21:41815772-41818348,
chr21:41609930-41611263~~chr21:41815839-41818255,
chr21:41609937-41611206~~chr21:41815911-41818342,
chr21:41609940-41611371~~chr21:41815790-41818726,
chr21:41609941-41611279~~chr21:41815811-41818198,
chr21:41609947-41611362~~chr21:41815821-41818177,
chr21:41611316-41613965~~chr21:41815851-41818361,
chr21:41611361-41613736~~chr21:41815847-41818243,
chr21:41611373-41613994~~chr21:41815828-41818342,
chr21:41611386-41613766~~chr21:41815816-41818179,
chr21:41611455-41613750~~chr21:41815821-41818177,
chr21:41611455-41613992~~chr21:41815837-41818350,
chr21:41611457-41614038~~chr21:41815831-41818342,
chr21:41611484-41613992~~chr21:41815911-41818342,
chr21:41611484-41613992~~chr21:41877559-41880450,
chr21:41611486-41613958~~chr21:41815790-41818726,
chr21:41611491-41613751~~chr21:41815835-41818259,
chr21:41611517-41613753~~chr21:41815741-41818325,
chr21:41611527-41614046~~chr21:41815096-41818336,
chr21:41611554-41613773~~chr21:41815864-41818241,
chr21:41611555-41613782~~chr21:41815811-41818198,
chr21:41611561-41614052~~chr21:41815802-41818289,
chr21:41611562-41613730~~chr21:41815809-41818325,
chr21:41611565-41613926~~chr21:41815814-41818320,
chr21:41611575-41614001~~chr21:41815800-41818285,
chr21:41611576-41614069~~chr21:41815809-41818141,
chr21:41611599-41613731~~chr21:41815787-41818293,
chr21:41611600-41614022~~chr21:41815737-41818351,
chr21:41611601-41613745~~chr21:41815797-41818318,
chr21:41611601-41613764~~chr21:41815824-41818136,
chr21:41611602-41613913~~chr21:41815835-41818294,
chr21:41611606-41613722~~chr21:41815780-41818270,
chr21:41611608-41614023~~chr21:41815839-41818255,
chr21:41611609-41613772~~chr21:41815812-41818317,
chr21:41611609-41614021~~chr21:41815809-41818765,
chr21:41611632-41613892~~chr21:41815997-41818148,
chr21:41611633-41613763~~chr21:41815801-41818255,
chr21:41611640-41613671~~chr21:41815868-41818188,
chr21:41611641-41613677~~chr21:41815910-41818235,
chr21:41611641-41614038~~chr21:41815999-41818227,
chr21:41611649-41613707~~chr21:41815737-41818316,
chr21:41611799-41613721~~chr21:41815785-41818093,
chr21:41611839-41613562~~chr21:41816062-41818083,
chr21:41625000-41650000~~chr21:41775000-41800000,
chr21:41725000-41750000~~chr21:41825000-41850000,
chr21:41750000-41775000~~chr21:41850000-41875000,
chr21:41775000-41800000~~chr21:41925000-41950000,
chr21:41775000-41800000~~chr21:42100000-42125000,
chr21:41800000-41825000~~chr21:42100000-42125000,
chr21:41800000-41825000~~chr21:42425000-42450000,
chr21:41800000-41825000~~chr21:42475000-42500000,
chr21:41800000-41825000~~chr21:42500000-42525000,
chr21:41800000-41825000~~chr21:42800000-42825000,
chr21:41802187-41803544~~chr21:42125243-42126817,
chr21:41815096-41818336~~chr21:42116276-42118975,
chr21:41815195-41818114~~chr21:42116443-42118958,
chr21:41815385-41818123~~chr21:42106891-42109246,
chr21:41815385-41818123~~chr21:42116645-42118612,
chr21:41815447-41818293~~chr21:42106952-42108805,
chr21:41815722-41818125~~chr21:41916406-41918311,
chr21:41815737-41818316~~chr21:41861143-41864113,
chr21:41815737-41818316~~chr21:41895209-41897144,
chr21:41815737-41818316~~chr21:42094326-42095544,
chr21:41815737-41818316~~chr21:42107070-42109056,
chr21:41815737-41818316~~chr21:42116480-42118891,
chr21:41815737-41818351~~chr21:42116256-42118602,
chr21:41815741-41818325~~chr21:41876469-41879286,
chr21:41815741-41818325~~chr21:41894768-41897068,
chr21:41815741-41818325~~chr21:41916134-41918303,
chr21:41815747-41818270~~chr21:42116587-42119641,
chr21:41815762-41818291~~chr21:42106954-42108828,
chr21:41815762-41818291~~chr21:42116742-42118600,
chr21:41815772-41818348~~chr21:41861159-41863293,
chr21:41815772-41818348~~chr21:41916377-41918020,
chr21:41815785-41818093~~chr21:42106648-42108930,
chr21:41815785-41818093~~chr21:42116635-42118386,
chr21:41815787-41818293~~chr21:41916417-41918064,
chr21:41815787-41818293~~chr21:41931609-41933343,
chr21:41815790-41818726~~chr21:42116679-42118765,
chr21:41815797-41818318~~chr21:42116717-42118997,
chr21:41815801-41818255~~chr21:42116652-42118623,
chr21:41815802-41818289~~chr21:42116718-42118814,
chr21:41815809-41818325~~chr21:42116692-42118897,
chr21:41815809-41818765~~chr21:42116737-42118378,
chr21:41815822-41818125~~chr21:42116708-42118554,
chr21:41815837-41818350~~chr21:42116767-42118662,
chr21:41815837-41818350~~chr21:42125269-42126883,
chr21:41815839-41818255~~chr21:42116749-42118385,
chr21:41815923-41818297~~chr21:42106594-42109053,
chr21:41815923-41818297~~chr21:42116811-42119739,
chr21:41816016-41818176~~chr21:42116818-42119705,
chr21:41816044-41818153~~chr21:42116850-42119542,
chr21:41816062-41818083~~chr21:42107290-42108688,
chr21:41816081-41818131~~chr21:42116778-42118373,
chr21:41816104-41818123~~chr21:41861421-41862854,
chr21:41825000-41850000~~chr21:42100000-42125000,
chr21:41825000-41850000~~chr21:42275000-42300000,
chr21:41825000-41850000~~chr21:42425000-42450000,
chr21:41832160-41834589~~chr21:41867750-41870564,
chr21:41832160-41834589~~chr21:41876469-41879286,
chr21:41846872-41848292~~chr21:42116256-42118602,
chr21:41850000-41875000~~chr21:41950000-41975000,
chr21:41850000-41875000~~chr21:42050000-42075000,
chr21:41850000-41875000~~chr21:42075000-42100000,
chr21:41850000-41875000~~chr21:42100000-42125000,
chr21:41850000-41875000~~chr21:42225000-42250000,
chr21:41850000-41875000~~chr21:42275000-42300000,
chr21:41872516-41873998~~chr21:42116737-42118378,
chr21:41875000-41900000~~chr21:41975000-42000000,
chr21:41875000-41900000~~chr21:42000000-42025000,
chr21:41875000-41900000~~chr21:42100000-42125000,
chr21:41876408-41880502~~chr21:42116480-42118891,
chr21:41877545-41880451~~chr21:42008763-42011946,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
GSE95015, 4DNFITUOMFUQ, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, 4DNFIZ4F74QR, 4DNFIO8HVKOL, ENCSR350NJV, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFI9VXTBE2, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, GSE99541, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR000FDB, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, ENCSR146FPM, 4DNFIOX3BGNE, ENCSR478BMT, GSE69643, GSE155380, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, GSE80820, 4DNFIBT4EAKN, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIH9U4I7I, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, ENCSR778FXH, 4DNFI9ZWZ5BS, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIBRSIPE4, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, 4DNFIPV5KFMK, ENCSR672RHL, 4DNFIW8TIFI5, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, ENCSR444BAR, ENCSR123UVP, ENCSR550JLK, 4DNFIM2BMJ33, 4DNFIALNLR78, 4DNFIBY3UHJB, ENCSR386KHY, ENCSR379CII, 4DNFIEJEFCAM, 4DNFIQRTP7NM, ENCSR393LOP, GSE44267, GSE125243, 4DNFIPAF4PYT, ENCSR255XYX, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, ENCSR094EIC, GSE58752, GSE116869, 4DNFIRZA6EV6, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFIILDWK8M, ENCSR866FWQ, 4DNFI6EIFUZI, 4DNFII6AN691, GSE111537, GSE131580, ENCSR381DCY, ENCSR981FNA, 4DNFIOUSETUP, ENCSR752QCX, ENCSR128RPG, 4DNFISTWNV9C, GSE101921, ENCSR228TUX, 4DNFI8JFOAJT, 4DNFIQVMVRP6, 4DNFIC3HAU11, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFIP71EWXC, 4DNFIHN2QSMX, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: U2OS,HL-60,SLK,P3HR-1
- Cohesin-DEGs, number of studies: 5
- Cohesin-DEGs, study: GSE140651,GSE131581,GSE138937,GSE89799
- Cohesin-DEGs, subunit: CTCF,SMC1,Rad21,SA2