Deatailed information for gene ENSG00000142166
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00008197
- Gene Symbol: IFNAR1
- Ensembl ID: ENSG00000142166
-
Gene locus: chr21:33324969-33359864
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-32652266-32654844,
chr21-32726512-32729587,
chr21-32732552-32732879,
chr21-32824831-32828372,
chr21-32830402-32830634,
chr21-32831636-32833765,
chr21-32834854-32835342,
chr21-32836285-32836542,
chr21-32844499-32845578,
chr21-32846527-32846785,
chr21-32926434-32926668,
chr21-32929569-32931312,
chr21-32931964-32933359,
chr21-32934017-32934551,
chr21-32938921-32942303,
chr21-32943893-32944726,
chr21-32948912-32949468,
chr21-32951208-32951430,
chr21-32955846-32956667,
chr21-32958326-32958988,
chr21-32961985-32962736,
chr21-32965025-32966085,
chr21-32968711-32969012,
chr21-32970880-32971243,
chr21-32973939-32974357,
chr21-33018853-33032029,
chr21-33032493-33034874,
chr21-33035105-33037170,
chr21-33039667-33039909,
chr21-33040959-33041685,
chr21-33042060-33043831,
chr21-33046659-33047090,
chr21-33047338-33047839,
chr21-33049543-33050194,
chr21-33176533-33177231,
chr21-33178927-33179239,
chr21-33180031-33180867,
chr21-33181665-33182455,
chr21-33183559-33184328,
chr21-33185051-33185236,
chr21-33185475-33185847,
chr21-33186452-33186919,
chr21-33189336-33190586,
chr21-33191132-33191643,
chr21-33192567-33193025,
chr21-33193411-33193657,
chr21-33194152-33195061,
chr21-33195338-33206151,
chr21-33206645-33209519,
chr21-33209798-33210131,
chr21-33211272-33213452,
chr21-33215011-33217335,
chr21-33219732-33220309,
chr21-33222873-33223242,
chr21-33224686-33226597,
chr21-33248634-33250562,
chr21-33251697-33253100,
chr21-33253758-33254062,
chr21-33255336-33255889,
chr21-33257059-33258358,
chr21-33259241-33262524,
chr21-33263925-33265036,
chr21-33265360-33271071,
chr21-33271445-33271897,
chr21-33272560-33273289,
chr21-33321044-33321781,
chr21-33322068-33327091,
chr21-33327900-33328437,
chr21-33328733-33329063,
chr21-33330820-33332435,
chr21-33332687-33333184,
chr21-33333599-33333915,
chr21-33334567-33335084,
chr21-33337603-33338145,
chr21-33338686-33340327,
chr21-33340630-33341347,
chr21-33341696-33343063,
chr21-33343933-33344156,
chr21-33346315-33351403,
chr21-33354048-33354418,
chr21-33355143-33356443,
chr21-33356778-33357973,
chr21-33359012-33364862,
chr21-33372144-33385560,
chr21-33423966-33426664,
chr21-33427110-33427633,
chr21-33428595-33430128,
chr21-33430846-33431848,
chr21-33432435-33436842,
chr21-33437463-33438154,
chr21-33438470-33439663,
chr21-33440299-33447453,
chr21-33448010-33448871,
chr21-33449679-33449894,
chr21-33450273-33450522,
chr21-33451723-33452456,
chr21-33456202-33456396,
chr21-33463002-33463264,
chr21-33464168-33464731,
chr21-33465490-33466234,
chr21-33467295-33467688,
chr21-33470245-33470858,
chr21-33471801-33472724,
chr21-33474539-33475875,
chr21-33600574-33601299,
chr21-33603909-33604583,
chr21-33605200-33607038,
chr21-33607346-33608402,
chr21-33608659-33608932,
chr21-33609731-33610466,
chr21-33610749-33611018,
chr21-33612271-33612631,
chr21-33616311-33616612,
chr21-33617012-33618282,
chr21-33620585-33621673,
chr21-33622979-33623244,
chr21-33624861-33625767,
-
Co-expression with cohesin genes Rho = 0.5983
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.200
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.866
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MCF-10A,GM12892,K1,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,K-562,A-549,HFFc6,PAEC,HeLa-S3,SU-DHL-2,H9-hESC,NCI-H1437,Liver,Germinal-Center-B,HT-1197,Kelly,H1-hESC,HT-1376,GM19238,Motor-Neuron,MSLCL,NaiveB,HUES64,SU-DHL-4,RT-112,Jurkat,CC-2551,HFF-hTERT,HAP1,MCF7-FASR
- Related loop:
chr21:32652779-32654447~~chr21:33360228-33362109,
chr21:32725000-32750000~~chr21:33350000-33375000,
chr21:32825000-32850000~~chr21:33300000-33325000,
chr21:32825000-32850000~~chr21:33350000-33375000,
chr21:32925000-32950000~~chr21:33325000-33350000,
chr21:32950000-32975000~~chr21:33300000-33325000,
chr21:33025000-33050000~~chr21:33325000-33350000,
chr21:33175000-33200000~~chr21:33350000-33375000,
chr21:33199037-33200983~~chr21:33360047-33362483,
chr21:33199045-33200951~~chr21:33360197-33362875,
chr21:33199050-33200800~~chr21:33360051-33362614,
chr21:33199054-33200784~~chr21:33360453-33362457,
chr21:33199055-33201024~~chr21:33360153-33362582,
chr21:33199061-33200994~~chr21:33360009-33362674,
chr21:33199063-33200997~~chr21:33360045-33362734,
chr21:33199071-33200963~~chr21:33360153-33362100,
chr21:33199075-33200850~~chr21:33360213-33362978,
chr21:33199075-33200916~~chr21:33360017-33362749,
chr21:33199076-33200916~~chr21:33360130-33362524,
chr21:33199079-33200988~~chr21:33360176-33362505,
chr21:33199086-33200764~~chr21:33360477-33362524,
chr21:33199100-33200791~~chr21:33360203-33362100,
chr21:33199124-33200675~~chr21:33360104-33362934,
chr21:33199158-33200742~~chr21:33360558-33362130,
chr21:33200000-33225000~~chr21:33300000-33325000,
chr21:33200000-33225000~~chr21:33325000-33350000,
chr21:33200000-33225000~~chr21:33350000-33375000,
chr21:33250000-33275000~~chr21:33350000-33375000,
chr21:33325000-33350000~~chr21:33425000-33450000,
chr21:33325000-33350000~~chr21:33450000-33475000,
chr21:33350000-33375000~~chr21:33450000-33475000,
chr21:33350000-33375000~~chr21:33600000-33625000,
chr21:33360009-33362674~~chr21:33444395-33446546,
chr21:33360017-33362749~~chr21:33373161-33376136,
chr21:33360017-33362749~~chr21:33444399-33446509,
chr21:33360045-33362734~~chr21:33444390-33446463,
chr21:33360121-33362991~~chr21:33373327-33376082,
chr21:33360121-33362991~~chr21:33444374-33446510,
chr21:33360130-33362524~~chr21:33444431-33446547,
chr21:33360132-33362704~~chr21:33444396-33446544,
chr21:33360151-33362730~~chr21:33373805-33376073,
chr21:33360151-33362730~~chr21:33443867-33446335,
chr21:33360153-33362582~~chr21:33444393-33446535,
chr21:33360157-33362875~~chr21:33444546-33446097,
chr21:33360173-33362129~~chr21:33444604-33446075,
chr21:33360203-33362100~~chr21:33444407-33446481,
chr21:33360213-33362978~~chr21:33444400-33446333,
chr21:33360224-33362415~~chr21:33444418-33446468,
chr21:33360228-33362109~~chr21:33444451-33446541,
chr21:33360313-33362104~~chr21:33444549-33446058,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQWD8ZYD, 4DNFI8649RQJ, 4DNFI3CFMRID, ENCSR662QKG, GSE95015, GSE43070, 4DNFI5CGQ46V, 4DNFIMROE6N4, GSE118716, 4DNFIE8E4ANZ, ENCSR499RVD, 4DNFIB7QTIMH, GSE108787, 4DNFI5SUHCGZ, GSE84022, GSE120294, ENCSR361AYD, GSE103148, 4DNFI7H4II2V, 4DNFIZ4F74QR, 4DNFIMEG1QIC, 4DNFIF2D3TL9, 4DNFIA6NSSBJ, ENCSR668RDP, GSE155380, ENCSR981FNA, GSE97394, ENCSR587DSF, ENCSR452NHL, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFIXGXD67I, ENCSR128RPG, 4DNFI9YAVTI1, 4DNFIBT4EAKN, GSE52457, GSE80820, ENCSR658RQQ, 4DNFIM2BMJ33, ENCSR299VMZ, ENCSR314HAC, ENCSR479MTN, Direct, 4DNFIAS8LV1C, 4DNFISPUVQHA, ENCSR386KHY, 4DNFI8Y9SRP2, 4DNFIX7H3CE2, GSE101921, 4DNFII84FBKM, ENCSR244BBG, ENCSR228TUX, 4DNFI8JFOAJT, ENCSR393LOP, GSE44267, ENCSR991JXX, 4DNFIPAF4PYT, 4DNFIQVMVRP6, ENCSR305RTT, GSE48592, ENCSR338WUS, 4DNFIE5TEYK7, 4DNFIVJ3IIQL, ENCSR527RXH, ENCSR933UZH, ENCSR833CMG, 4DNFIDBIEXI7, 4DNFIDKJFK2S, 4DNFIFLJLIS5, 4DNFIZGCA8AH, 4DNFIHN2QSMX, GSE58752, GSE105028, ENCSR033GUP
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: HL-60,SLK,HPC,P3HR-1,U2OS,HeLa-S3
- Cohesin-DEGs, number of studies: 8
- Cohesin-DEGs, study: GSE89799,GSE140651,GSE131581,GSE119828,GSE138937,GSE108869,GSE130558
- Cohesin-DEGs, subunit: SA2,WAPL,CTCF,SMC1,Rad21,CdLS