Deatailed information for gene ENSG00000142168
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00008198
- Gene Symbol: SOD1
- Ensembl ID: ENSG00000142168
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Gene locus: chr21:31659692-31668931
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-31623474-31624174,
chr21-31624761-31625676,
chr21-31646734-31647539,
chr21-31648123-31648567,
chr21-31653945-31655332,
chr21-31656215-31656718,
chr21-31657094-31661124,
chr21-31661359-31661750,
chr21-31662774-31663049,
chr21-31663515-31663715,
chr21-31663969-31664248,
chr21-31664667-31664997,
chr21-31665442-31665775,
chr21-31666075-31666304,
chr21-31669061-31669469,
chr21-31671850-31672401,
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Co-expression with cohesin genes Rho = 0.4410
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.190
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.901
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: SU-DHL-2,SU-DHL-4,GM12878,H1-hESC
- Related loop:
chr21:27500000-27525000~~chr21:31650000-31675000,
chr21:31622545-31624738~~chr21:31658893-31661227,
chr21:31622573-31624872~~chr21:31665039-31666300,
chr21:31622928-31624476~~chr21:31665036-31666246,
chr21:31647206-31648984~~chr21:31658893-31661227,
chr21:31650000-31675000~~chr21:39175000-39200000,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
ENCSR128RPG, 4DNFIQYQWPF5, ENCSR658RQQ, Direct, ENCSR981FNA, 4DNFIIMZB6Y9, ENCSR410MDC
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: HL-60,SLK,Kelly,U2OS,HeLa-S3
- Cohesin-DEGs, number of studies: 6
- Cohesin-DEGs, study: GSE115253,GSE131581,GSE138937,GSE89799,GSE130558
- Cohesin-DEGs, subunit: WAPL,Rad21,SA2,BORIS