Deatailed information for gene ENSG00000142185
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00008202
- Gene Symbol: TRPM2
- Ensembl ID: ENSG00000142185
-
Gene locus: chr21:44350162-44443081
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-42524067-42525788,
chr21-42526135-42528623,
chr21-42528891-42529866,
chr21-42530287-42531423,
chr21-42532164-42534148,
chr21-42534381-42538581,
chr21-42538854-42540670,
chr21-42540899-42541525,
chr21-42542597-42549588,
chr21-42971699-42976556,
chr21-42977567-42978245,
chr21-42978524-42979165,
chr21-42979449-42979775,
chr21-42980073-42980693,
chr21-42981060-42983699,
chr21-42984049-42984123,
chr21-42984399-42985953,
chr21-42986206-42987380,
chr21-42987592-42989052,
chr21-42989441-42990324,
chr21-42991464-42993497,
chr21-42993747-42994516,
chr21-42996864-42997865,
chr21-42998695-42999369,
chr21-43167531-43179410,
chr21-43179782-43180289,
chr21-43180997-43181922,
chr21-43186619-43189146,
chr21-43189488-43189736,
chr21-43190641-43195980,
chr21-43196363-43198075,
chr21-43202414-43202849,
chr21-43203180-43204296,
chr21-43205526-43206063,
chr21-43206324-43207655,
chr21-43207866-43208349,
chr21-43208557-43212285,
chr21-43328508-43351938,
chr21-43352261-43357227,
chr21-43357471-43370764,
chr21-43371758-43372139,
chr21-43372411-43378616,
chr21-43574497-43576116,
chr21-43576516-43576782,
chr21-43578473-43579527,
chr21-43581013-43581404,
chr21-43581641-43582576,
chr21-43582859-43583337,
chr21-43583553-43584232,
chr21-43584938-43588325,
chr21-43589018-43591020,
chr21-43591407-43592525,
chr21-43592960-43594483,
chr21-43595004-43602071,
chr21-43650183-43650609,
chr21-43652784-43653261,
chr21-43653524-43654073,
chr21-43654592-43655821,
chr21-43657025-43661637,
chr21-43663113-43663746,
chr21-43665582-43666779,
chr21-43667345-43668735,
chr21-43669130-43669692,
chr21-43669978-43670612,
chr21-43671144-43671960,
chr21-43672190-43672490,
chr21-43673349-43673603,
chr21-43745728-43760952,
chr21-43761154-43780032,
chr21-43796477-43821123,
chr21-43821535-43822584,
chr21-43823281-43831732,
chr21-43899414-43901125,
chr21-43902347-43902875,
chr21-43903389-43904929,
chr21-43905740-43906024,
chr21-43906608-43910716,
chr21-43911097-43912991,
chr21-43913332-43914290,
chr21-43914602-43914828,
chr21-43915079-43915725,
chr21-43916632-43919024,
chr21-43919860-43926811,
chr21-43999790-44003430,
chr21-44003656-44007434,
chr21-44007816-44008392,
chr21-44008742-44009011,
chr21-44009756-44016003,
chr21-44016585-44017233,
chr21-44018250-44019461,
chr21-44019691-44020615,
chr21-44021146-44022462,
chr21-44022967-44023469,
chr21-44024829-44026370,
chr21-44049059-44050644,
chr21-44051500-44052149,
chr21-44058034-44059019,
chr21-44060331-44060715,
chr21-44061133-44061570,
chr21-44062415-44062878,
chr21-44063088-44064391,
chr21-44065260-44065880,
chr21-44066159-44066445,
chr21-44067082-44068169,
chr21-44069413-44070104,
chr21-44070382-44070916,
chr21-44071581-44073072,
chr21-44074197-44074929,
chr21-44077348-44077570,
chr21-44078553-44078867,
chr21-44079138-44079687,
chr21-44081500-44084368,
chr21-44084897-44085581,
chr21-44086043-44086366,
chr21-44086762-44089972,
chr21-44090357-44091197,
chr21-44093882-44094111,
chr21-44094969-44096191,
chr21-44173865-44179849,
chr21-44180238-44182493,
chr21-44184317-44187032,
chr21-44188310-44188648,
chr21-44190305-44191390,
chr21-44192164-44195002,
chr21-44195889-44198272,
chr21-44199123-44199370,
chr21-44199741-44200119,
chr21-44320741-44336654,
chr21-44337821-44343795,
chr21-44344069-44346159,
chr21-44347920-44356379,
chr21-44356673-44361513,
chr21-44362261-44362548,
chr21-44362803-44363087,
chr21-44363857-44367810,
chr21-44368175-44372791,
chr21-44373234-44373624,
chr21-44374000-44381319,
chr21-44382365-44382932,
chr21-44383256-44383547,
chr21-44390572-44392392,
chr21-44393048-44393242,
chr21-44394010-44394651,
chr21-44395263-44395926,
chr21-44396214-44397136,
chr21-44397384-44398184,
chr21-44398443-44398768,
chr21-44399049-44404076,
chr21-44404560-44407011,
chr21-44407609-44407831,
chr21-44408040-44408353,
chr21-44408622-44408985,
chr21-44409770-44410108,
chr21-44413245-44419872,
chr21-44420223-44421308,
chr21-44421775-44422476,
chr21-44423218-44429069,
chr21-44430427-44430776,
chr21-44431429-44432042,
chr21-44432556-44445133,
chr21-44445469-44446997,
chr21-44447926-44448241,
chr21-44448540-44449289,
chr21-44449493-44451537,
chr21-44454404-44458504,
chr21-44458902-44463283,
chr21-44463692-44468246,
chr21-44470353-44470718,
chr21-44471953-44472348,
chr21-44474024-44474470,
chr21-44474734-44475102,
chr21-44477225-44484621,
chr21-44484854-44488529,
chr21-44488757-44489043,
chr21-44489948-44491135,
chr21-44493207-44494864,
chr21-44495074-44495354,
chr21-44496153-44497242,
chr21-44498019-44500523,
chr21-44699438-44700075,
chr21-44700276-44701276,
chr21-44701494-44705032,
chr21-44705399-44713548,
chr21-44716685-44716835,
chr21-44718430-44719031,
chr21-44721222-44721639,
chr21-44721934-44722192,
chr21-44723185-44724478,
chr21-44724719-44725397,
chr21-44726838-44728488,
chr21-44729260-44730345,
chr21-44730663-44731098,
chr21-44731456-44731919,
chr21-44732256-44737281,
chr21-44737533-44737682,
chr21-44738634-44738881,
chr21-44740003-44740352,
chr21-44741922-44744934,
chr21-44747978-44748295,
chr21-44748543-44754678,
chr21-44755085-44756295,
chr21-44756826-44769032,
chr21-44769388-44770132,
chr21-44770932-44775360,
chr21-44775568-44776159,
chr21-44778211-44780009,
chr21-44780867-44781685,
chr21-44784599-44786454,
chr21-44786700-44787596,
chr21-44788341-44788598,
chr21-44789666-44790323,
chr21-44791310-44795621,
chr21-44797363-44798119,
chr21-44799103-44805501,
chr21-44806825-44807985,
chr21-44808233-44808856,
chr21-44809850-44811758,
chr21-44812135-44814175,
chr21-44814747-44820942,
chr21-44823998-44825617,
chr21-44842094-44850066,
chr21-44850330-44851998,
chr21-44852235-44856871,
chr21-44857206-44857817,
chr21-44858153-44859485,
chr21-44860020-44862529,
chr21-44862997-44876511,
chr21-44876848-44922035,
chr21-44922496-44936465,
chr21-44937160-44937800,
chr21-44938036-44942579,
chr21-44943111-44946058,
chr21-44946260-44956117,
chr21-45124436-45132048,
chr21-45132786-45143934,
chr21-45145219-45145603,
chr21-45145953-45146151,
chr21-45147401-45149408,
chr21-45199827-45201411,
chr21-45201822-45203368,
chr21-45205334-45205638,
chr21-45206724-45207526,
chr21-45208102-45208832,
chr21-45209175-45210299,
chr21-45210540-45211407,
chr21-45211669-45211971,
chr21-45212249-45212719,
chr21-45218184-45218795,
chr21-45220299-45221191,
chr21-45221574-45224852,
chr21-45316533-45338135,
chr21-45339035-45339421,
chr21-45340328-45340876,
chr21-45341176-45342108,
chr21-45342847-45354233,
chr21-45487915-45502397,
chr21-45502617-45502900,
chr21-45503606-45519118,
chr21-45522806-45526243,
chr21-45526587-45546954,
chr21-45549108-45549455,
chr21-45549738-45561026,
chr21-45625655-45625928,
chr21-45629009-45638293,
chr21-45639143-45646446,
chr21-45725399-45726825,
chr21-45727437-45727820,
chr21-45733296-45733630,
chr21-45734384-45735074,
chr21-45736308-45737991,
chr21-45738350-45741362,
chr21-45741837-45742013,
chr21-45744922-45747032,
chr21-45747248-45748980,
chr21-45824560-45825827,
chr21-45826840-45830627,
chr21-45830839-45831391,
chr21-45831779-45832772,
chr21-45833478-45836709,
chr21-45837172-45837882,
chr21-45844115-45844699,
chr21-45845305-45846222,
chr21-45846697-45847005,
chr21-45847320-45849116,
-
Co-expression with cohesin genes Rho = 0.1092
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.554
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.844
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MCF-10A,TAMR-MCF7,MB157,H1-Mesenchymal,H1-Mesendoderm,MCF-7,HEK293T,GM12878,K-562,A-549,HFFc6,HeLa-S3,H1-Trophectoderm,H9-hESC,Liver,REC-1,HCT-116,Germinal-Center-B,H1-hESC,HCC1599,Motor-Neuron,NaiveB,U-937,BMEC,HUES64,HUVEC,HL-60,NPC-H9,RT-112,KBM-7,HFF-hTERT,HAP1,MCF7-FASR
- Related loop:
chr21:42525000-42550000~~chr21:44325000-44350000,
chr21:42975000-43000000~~chr21:44325000-44350000,
chr21:43175000-43200000~~chr21:44375000-44400000,
chr21:43200000-43225000~~chr21:44350000-44375000,
chr21:43350000-43375000~~chr21:44325000-44350000,
chr21:43350000-43375000~~chr21:44375000-44400000,
chr21:43350000-43375000~~chr21:44425000-44450000,
chr21:43575000-43600000~~chr21:44325000-44350000,
chr21:43650000-43675000~~chr21:44325000-44350000,
chr21:43750000-43775000~~chr21:44325000-44350000,
chr21:43800000-43825000~~chr21:44425000-44450000,
chr21:43900000-43925000~~chr21:44425000-44450000,
chr21:44000000-44025000~~chr21:44325000-44350000,
chr21:44050000-44075000~~chr21:44425000-44450000,
chr21:44075000-44100000~~chr21:44325000-44350000,
chr21:44075000-44100000~~chr21:44425000-44450000,
chr21:44175000-44200000~~chr21:44325000-44350000,
chr21:44325000-44350000~~chr21:44425000-44450000,
chr21:44325000-44350000~~chr21:44450000-44475000,
chr21:44325000-44350000~~chr21:44475000-44500000,
chr21:44325000-44350000~~chr21:44700000-44725000,
chr21:44325000-44350000~~chr21:44725000-44750000,
chr21:44325000-44350000~~chr21:44750000-44775000,
chr21:44325000-44350000~~chr21:44775000-44800000,
chr21:44325000-44350000~~chr21:44800000-44825000,
chr21:44325000-44350000~~chr21:44850000-44875000,
chr21:44325000-44350000~~chr21:44875000-44900000,
chr21:44325000-44350000~~chr21:44900000-44925000,
chr21:44325000-44350000~~chr21:44925000-44950000,
chr21:44325000-44350000~~chr21:45125000-45150000,
chr21:44325000-44350000~~chr21:45325000-45350000,
chr21:44325000-44350000~~chr21:45500000-45525000,
chr21:44325000-44350000~~chr21:45525000-45550000,
chr21:44325000-44350000~~chr21:45625000-45650000,
chr21:44325000-44350000~~chr21:45825000-45850000,
chr21:44350000-44375000~~chr21:44450000-44475000,
chr21:44350000-44375000~~chr21:44475000-44500000,
chr21:44350000-44375000~~chr21:44725000-44750000,
chr21:44350000-44375000~~chr21:44750000-44775000,
chr21:44350000-44375000~~chr21:44775000-44800000,
chr21:44350000-44375000~~chr21:45125000-45150000,
chr21:44350000-44375000~~chr21:45200000-45225000,
chr21:44375000-44400000~~chr21:44475000-44500000,
chr21:44375000-44400000~~chr21:44725000-44750000,
chr21:44375000-44400000~~chr21:45725000-45750000,
chr21:44376561-44378522~~chr21:44438718-44440053,
chr21:5100000-5125000~~chr21:44325000-44350000,
chr21:5100000-5125000~~chr21:44425000-44450000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
GSE95015, 4DNFIHMCILEN, GSE43070, 4DNFIDJ2JZ7Q, 4DNFIBN9K4V9, ENCSR852KQC, 4DNFIZ4F74QR, 4DNFI7H4II2V, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, GSE99541, GSE97394, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFI8Y9SRP2, 4DNFIK61ILGM, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, GSE105028, 4DNFI3CFMRID, ENCSR662QKG, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, 4DNFIBXWIH8J, 4DNFIJWBWE41, GSE155380, 4DNFIIMZB6Y9, GSE80820, GSE52457, Direct, 4DNFIV56OFE3, ENCSR244BBG, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIT96Z365, 4DNFIH2A7IKF, 4DNFIWZEN3FF, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIBM714BP, 4DNFIFHU75I5, 4DNFIYD8LO9Z, 4DNFI3A3VYWU, 4DNFIM2BMJ33, GSE165038, 4DNFIALNLR78, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, GSE48592, 4DNFIE5TEYK7, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, GSE58752, GSE116869, ENCSR507AHE, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFIBCIA62Q, 4DNFII6AN691, GSE131580, 4DNFIV239W4L, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, 4DNFI8JFOAJT, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, 4DNFINEQY95T, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: SLK,OCI-AML-3,K-562,MCF-10A,Fibroblast,CordBlood
- Cohesin-DEGs, number of studies: 9
- Cohesin-DEGs, study: GSE73224,GSE111537,GSE101921,GSE154086,GSE131448,GSE138937,SRP050576
- Cohesin-DEGs, subunit: CdLS,CTCF,Rad21,SA2