Deatailed information for gene ENSG00000142197
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00008206
- Gene Symbol: DOP1B
- Ensembl ID: ENSG00000142197
-
Gene locus: chr21:36164534-36294274
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-34344734-34353465,
chr21-34355390-34355626,
chr21-34356201-34356732,
chr21-34360486-34364137,
chr21-34364518-34364800,
chr21-34365500-34365847,
chr21-34366487-34368638,
chr21-34369248-34369608,
chr21-34371955-34372730,
chr21-34373717-34374267,
chr21-34374742-34376256,
chr21-36050139-36050464,
chr21-36050926-36051294,
chr21-36052795-36053372,
chr21-36053850-36054250,
chr21-36054492-36054982,
chr21-36056537-36057152,
chr21-36058249-36058686,
chr21-36059201-36061295,
chr21-36063224-36064357,
chr21-36064608-36066514,
chr21-36069428-36070759,
chr21-36071001-36071885,
chr21-36072481-36072892,
chr21-36073158-36073998,
chr21-36076454-36076702,
chr21-36076908-36077195,
chr21-36077435-36078090,
chr21-36078788-36079629,
chr21-36079847-36080911,
chr21-36082978-36083967,
chr21-36086585-36086842,
chr21-36087214-36088155,
chr21-36096867-36098437,
chr21-36099272-36100281,
chr21-36125038-36126944,
chr21-36127229-36128557,
chr21-36128832-36129080,
chr21-36129740-36130699,
chr21-36132348-36133044,
chr21-36133297-36137447,
chr21-36138179-36138394,
chr21-36139440-36143477,
chr21-36143694-36144806,
chr21-36145249-36145917,
chr21-36146214-36147498,
chr21-36148387-36148829,
chr21-36149046-36149389,
chr21-36149733-36151341,
chr21-36152062-36154775,
chr21-36155298-36159915,
chr21-36160348-36160929,
chr21-36162643-36163290,
chr21-36163793-36164976,
chr21-36165429-36166440,
chr21-36166692-36167478,
chr21-36167980-36168299,
chr21-36169044-36170570,
chr21-36171056-36173134,
chr21-36173521-36174893,
chr21-36175175-36175489,
chr21-36175944-36176604,
chr21-36176844-36177305,
chr21-36178285-36178970,
chr21-36180358-36184886,
chr21-36185489-36190732,
chr21-36191345-36191818,
chr21-36192532-36196146,
chr21-36196672-36199361,
chr21-36199941-36200843,
chr21-36201956-36204277,
chr21-36204496-36205970,
chr21-36207279-36213059,
chr21-36213261-36213784,
chr21-36215461-36216010,
chr21-36220646-36222170,
chr21-36224193-36224492,
chr21-36225295-36225749,
chr21-36226428-36227844,
chr21-36228278-36228734,
chr21-36229199-36230147,
chr21-36230544-36231198,
chr21-36231686-36233549,
chr21-36233845-36235845,
chr21-36236082-36238447,
chr21-36238704-36240434,
chr21-36241048-36241641,
chr21-36242382-36242625,
chr21-36245119-36246670,
chr21-36246976-36247569,
chr21-36248900-36249494,
chr21-36250101-36251132,
chr21-36252668-36253134,
chr21-36253649-36256653,
chr21-36258997-36259715,
chr21-36260022-36261928,
chr21-36262223-36263216,
chr21-36265080-36265691,
chr21-36267726-36268314,
chr21-36268639-36269527,
chr21-36270588-36270906,
chr21-36271142-36271832,
chr21-36272357-36274134,
chr21-36274538-36275152,
chr21-36275378-36276136,
chr21-36276517-36277955,
chr21-36279183-36279563,
chr21-36280626-36281207,
chr21-36281766-36283404,
chr21-36284077-36285932,
chr21-36286346-36287760,
chr21-36288047-36291537,
chr21-36292334-36293482,
chr21-36294039-36294712,
chr21-36295324-36296187,
chr21-36296591-36299116,
chr21-36299999-36300920,
chr21-36301823-36302767,
chr21-36303173-36303417,
chr21-36306746-36307626,
chr21-36308895-36312325,
chr21-36312827-36313084,
chr21-36315963-36316373,
chr21-36316605-36317491,
chr21-36318095-36323464,
chr21-36323820-36325021,
chr21-36325365-36326460,
chr21-36326664-36327275,
chr21-36327639-36334205,
chr21-36334931-36335565,
chr21-36335925-36336565,
chr21-36336965-36337518,
chr21-36340013-36340333,
chr21-36340657-36340869,
chr21-36341931-36343741,
chr21-36345238-36346750,
chr21-36347303-36347666,
chr21-36348825-36349132,
chr21-36349796-36350705,
chr21-36353043-36353476,
chr21-36355218-36355790,
chr21-36358622-36359002,
chr21-36360808-36361089,
chr21-36369187-36370260,
chr21-36373061-36373546,
chr21-36374124-36374381,
chr21-36374655-36374977,
chr21-36379872-36380326,
chr21-36383536-36383931,
chr21-36384976-36386612,
chr21-36387795-36388181,
chr21-36388570-36390448,
chr21-36390697-36390999,
chr21-36392384-36394412,
chr21-36396999-36397241,
chr21-36399798-36400258,
chr21-36550406-36552372,
chr21-36552916-36553612,
chr21-36554114-36554596,
chr21-36555751-36555919,
chr21-36559148-36559503,
chr21-36561221-36561615,
chr21-36566551-36567815,
chr21-36568105-36568629,
chr21-36570859-36571195,
chr21-36573002-36573289,
chr21-36575350-36575709,
chr21-36576412-36577230,
chr21-36583668-36584068,
chr21-36584895-36585487,
chr21-36585745-36586353,
chr21-36587320-36592079,
chr21-36592299-36593515,
chr21-36594289-36594685,
chr21-36597896-36598145,
-
Co-expression with cohesin genes Rho = 0.1940
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.398
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.880
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,MB157,DU145,K1,hTERT-HME1,H1-Mesenchymal,Olfactory,Hepatocyte-H9,MCF-7,GM12891,GM12878,K-562,A-549,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,NCI-H1437,iPSC,HCT-116,Hep-G2,HT-1197,H1-hESC,HT-1376,GM19238,Motor-Neuron,NaiveB,HUES64,SU-DHL-4,NPC-H9,RT-112,Skin-Fibroblast,HFF-hTERT,HAP1,MCF7-FASR
- Related loop:
chr21:27500000-27525000~~chr21:36275000-36300000,
chr21:34350000-34375000~~chr21:36225000-36250000,
chr21:34350000-34375000~~chr21:36275000-36300000,
chr21:36050000-36075000~~chr21:36200000-36225000,
chr21:36075000-36100000~~chr21:36175000-36200000,
chr21:36125000-36150000~~chr21:36225000-36250000,
chr21:36140628-36142797~~chr21:36208896-36211059,
chr21:36140770-36142598~~chr21:36208928-36210883,
chr21:36140789-36142775~~chr21:36208898-36210957,
chr21:36140792-36142611~~chr21:36208845-36210808,
chr21:36140799-36142837~~chr21:36208339-36210839,
chr21:36140808-36142792~~chr21:36208893-36211062,
chr21:36140818-36142825~~chr21:36208180-36210735,
chr21:36140822-36142823~~chr21:36208825-36210883,
chr21:36140824-36142795~~chr21:36208849-36210862,
chr21:36140828-36142593~~chr21:36208784-36210767,
chr21:36140836-36142645~~chr21:36208979-36210847,
chr21:36140837-36142525~~chr21:36208955-36210590,
chr21:36140838-36142714~~chr21:36208696-36210781,
chr21:36140838-36142786~~chr21:36208808-36211018,
chr21:36140843-36142531~~chr21:36208942-36210568,
chr21:36140848-36142815~~chr21:36208865-36210865,
chr21:36140849-36142584~~chr21:36208920-36210789,
chr21:36140850-36142837~~chr21:36208890-36210845,
chr21:36140852-36142557~~chr21:36208778-36210979,
chr21:36140862-36142780~~chr21:36208188-36210796,
chr21:36140863-36142602~~chr21:36208770-36210834,
chr21:36140866-36142633~~chr21:36208896-36210832,
chr21:36140870-36142745~~chr21:36209005-36210744,
chr21:36140871-36142703~~chr21:36208897-36210863,
chr21:36150000-36175000~~chr21:36300000-36325000,
chr21:36150000-36175000~~chr21:36325000-36350000,
chr21:36150000-36175000~~chr21:36375000-36400000,
chr21:36150000-36175000~~chr21:39175000-39200000,
chr21:36150000-36175000~~chr21:46175000-46200000,
chr21:36152011-36154258~~chr21:36208885-36210840,
chr21:36152043-36154290~~chr21:36208880-36210854,
chr21:36152093-36154114~~chr21:36208893-36211062,
chr21:36152185-36154228~~chr21:36208896-36210870,
chr21:36152191-36154260~~chr21:36208896-36210832,
chr21:36152213-36154154~~chr21:36208928-36210883,
chr21:36152221-36154080~~chr21:36208180-36210735,
chr21:36152227-36154127~~chr21:36208825-36210883,
chr21:36152242-36154206~~chr21:36208896-36211059,
chr21:36152248-36154241~~chr21:36187568-36189319,
chr21:36152248-36154241~~chr21:36208696-36210781,
chr21:36152259-36154196~~chr21:36208897-36210863,
chr21:36152272-36154246~~chr21:36208777-36210982,
chr21:36152322-36154109~~chr21:36208843-36210788,
chr21:36152382-36154180~~chr21:36208778-36210979,
chr21:36152395-36154141~~chr21:36208770-36210834,
chr21:36152396-36154049~~chr21:36208182-36211280,
chr21:36152486-36154104~~chr21:36208903-36211039,
chr21:36152494-36154153~~chr21:36208813-36210759,
chr21:36152513-36154017~~chr21:36208784-36210767,
chr21:36155171-36156841~~chr21:36208778-36210979,
chr21:36155462-36156722~~chr21:36208903-36211039,
chr21:36155654-36157667~~chr21:36208890-36210845,
chr21:36155654-36157667~~chr21:36259462-36261497,
chr21:36175000-36200000~~chr21:36350000-36375000,
chr21:36175000-36200000~~chr21:36575000-36600000,
chr21:36181050-36182274~~chr21:36329784-36332238,
chr21:36187405-36189351~~chr21:36208897-36210863,
chr21:36187568-36189319~~chr21:36208696-36210781,
chr21:36200000-36225000~~chr21:36325000-36350000,
chr21:36200000-36225000~~chr21:36350000-36375000,
chr21:36200000-36225000~~chr21:36375000-36400000,
chr21:36208725-36210834~~chr21:36329820-36331841,
chr21:36208807-36210881~~chr21:36329776-36331875,
chr21:36208849-36210862~~chr21:36329821-36332549,
chr21:36208896-36211059~~chr21:36329784-36332238,
chr21:36208955-36210590~~chr21:36330185-36331807,
chr21:36209099-36210510~~chr21:36330219-36331784,
chr21:36209109-36210630~~chr21:36330220-36331778,
chr21:36209128-36210456~~chr21:36330409-36331736,
chr21:36225000-36250000~~chr21:36325000-36350000,
chr21:36245123-36246662~~chr21:36330384-36331754,
chr21:36245246-36246544~~chr21:36329821-36332549,
chr21:36250000-36275000~~chr21:36350000-36375000,
chr21:36250000-36275000~~chr21:36375000-36400000,
chr21:36250000-36275000~~chr21:36550000-36575000,
chr21:36253261-36254421~~chr21:36319310-36321320,
chr21:36259462-36261497~~chr21:36319312-36322600,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE95015, GSE43070, 4DNFIBN9K4V9, 4DNFI7H4II2V, 4DNFIREVU1Z5, ENCSR113OIR, 4DNFIRKGMZRQ, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, ENCSR658RQQ, ENCSR299VMZ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, ENCSR000FDB, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, 4DNFIQWD8ZYD, ENCSR662QKG, GSE118716, ENCSR146FPM, 4DNFIOX3BGNE, ENCSR478BMT, 4DNFIBXWIH8J, 4DNFIJWBWE41, 4DNFICSTCJQZ, GSE155380, ENCSR587DSF, 4DNFIIMZB6Y9, GSE80820, GSE52457, Direct, ENCSR314HAC, 4DNFIAS8LV1C, ENCSR244BBG, ENCSR991JXX, 4DNFI2J1ODWB, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIZGCA8AH, ENCSR194SRI, 4DNFIBRSIPE4, 4DNFIE8E4ANZ, GSE84022, ENCSR672RHL, ENCSR410MDC, ENCSR732QOH, 4DNFIFHU75I5, 4DNFI3A3VYWU, 4DNFIM2BMJ33, 4DNFIALNLR78, 4DNFIBY3UHJB, ENCSR386KHY, ENCSR393LOP, 4DNFIPAF4PYT, ENCSR255XYX, ENCSR404HWQ, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, GSE116869, 4DNFI8649RQJ, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR866FWQ, 4DNFI6EIFUZI, ENCSR381DCY, ENCSR981FNA, 4DNFIOUSETUP, ENCSR752QCX, ENCSR128RPG, 4DNFISTWNV9C, 4DNFI1UEG1HD, GSE101921, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR338WUS, 4DNFI5LCW273, 4DNFINEQY95T, 4DNFIVSCH2CH
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: HL-60,SLK,OCI-AML-3,K-562,MCF-10A,HAP1,HeLa-S3
- Cohesin-DEGs, number of studies: 12
- Cohesin-DEGs, study: GSE139845,GSE111537,GSE131581,GSE154086,GSE131448,GSE126635,GSE138937,GSE130558
- Cohesin-DEGs, subunit: SMC3,SA2,WAPL,CTCF,Rad21