Deatailed information for gene ENSG00000142197
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00008206
- Gene Symbol: DOP1B
- Ensembl ID: ENSG00000142197
- Gene locus: chr21:36164534-36294274 Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced): chr21-34344734-34353465, chr21-34355390-34355626, chr21-34356201-34356732, chr21-34360486-34364137, chr21-34364518-34364800, chr21-34365500-34365847, chr21-34366487-34368638, chr21-34369248-34369608, chr21-34371955-34372730, chr21-34373717-34374267, chr21-34374742-34376256, chr21-36050139-36050464, chr21-36050926-36051294, chr21-36052795-36053372, chr21-36053850-36054250, chr21-36054492-36054982, chr21-36056537-36057152, chr21-36058249-36058686, chr21-36059201-36061295, chr21-36063224-36064357, chr21-36064608-36066514, chr21-36069428-36070759, chr21-36071001-36071885, chr21-36072481-36072892, chr21-36073158-36073998, chr21-36076454-36076702, chr21-36076908-36077195, chr21-36077435-36078090, chr21-36078788-36079629, chr21-36079847-36080911, chr21-36082978-36083967, chr21-36086585-36086842, chr21-36087214-36088155, chr21-36096867-36098437, chr21-36099272-36100281, chr21-36125038-36126944, chr21-36127229-36128557, chr21-36128832-36129080, chr21-36129740-36130699, chr21-36132348-36133044, chr21-36133297-36137447, chr21-36138179-36138394, chr21-36139440-36143477, chr21-36143694-36144806, chr21-36145249-36145917, chr21-36146214-36147498, chr21-36148387-36148829, chr21-36149046-36149389, chr21-36149733-36151341, chr21-36152062-36154775, chr21-36155298-36159915, chr21-36160348-36160929, chr21-36162643-36163290, chr21-36163793-36164976, chr21-36165429-36166440, chr21-36166692-36167478, chr21-36167980-36168299, chr21-36169044-36170570, chr21-36171056-36173134, chr21-36173521-36174893, chr21-36175175-36175489, chr21-36175944-36176604, chr21-36176844-36177305, chr21-36178285-36178970, chr21-36180358-36184886, chr21-36185489-36190732, chr21-36191345-36191818, chr21-36192532-36196146, chr21-36196672-36199361, chr21-36199941-36200843, chr21-36201956-36204277, chr21-36204496-36205970, chr21-36207279-36213059, chr21-36213261-36213784, chr21-36215461-36216010, chr21-36220646-36222170, chr21-36224193-36224492, chr21-36225295-36225749, chr21-36226428-36227844, chr21-36228278-36228734, chr21-36229199-36230147, chr21-36230544-36231198, chr21-36231686-36233549, chr21-36233845-36235845, chr21-36236082-36238447, chr21-36238704-36240434, chr21-36241048-36241641, chr21-36242382-36242625, chr21-36245119-36246670, chr21-36246976-36247569, chr21-36248900-36249494, chr21-36250101-36251132, chr21-36252668-36253134, chr21-36253649-36256653, chr21-36258997-36259715, chr21-36260022-36261928, chr21-36262223-36263216, chr21-36265080-36265691, chr21-36267726-36268314, chr21-36268639-36269527, chr21-36270588-36270906, chr21-36271142-36271832, chr21-36272357-36274134, chr21-36274538-36275152, chr21-36275378-36276136, chr21-36276517-36277955, chr21-36279183-36279563, chr21-36280626-36281207, chr21-36281766-36283404, chr21-36284077-36285932, chr21-36286346-36287760, chr21-36288047-36291537, chr21-36292334-36293482, chr21-36294039-36294712, chr21-36295324-36296187, chr21-36296591-36299116, chr21-36299999-36300920, chr21-36301823-36302767, chr21-36303173-36303417, chr21-36306746-36307626, chr21-36308895-36312325, chr21-36312827-36313084, chr21-36315963-36316373, chr21-36316605-36317491, chr21-36318095-36323464, chr21-36323820-36325021, chr21-36325365-36326460, chr21-36326664-36327275, chr21-36327639-36334205, chr21-36334931-36335565, chr21-36335925-36336565, chr21-36336965-36337518, chr21-36340013-36340333, chr21-36340657-36340869, chr21-36341931-36343741, chr21-36345238-36346750, chr21-36347303-36347666, chr21-36348825-36349132, chr21-36349796-36350705, chr21-36353043-36353476, chr21-36355218-36355790, chr21-36358622-36359002, chr21-36360808-36361089, chr21-36369187-36370260, chr21-36373061-36373546, chr21-36374124-36374381, chr21-36374655-36374977, chr21-36379872-36380326, chr21-36383536-36383931, chr21-36384976-36386612, chr21-36387795-36388181, chr21-36388570-36390448, chr21-36390697-36390999, chr21-36392384-36394412, chr21-36396999-36397241, chr21-36399798-36400258, chr21-36550406-36552372, chr21-36552916-36553612, chr21-36554114-36554596, chr21-36555751-36555919, chr21-36559148-36559503, chr21-36561221-36561615, chr21-36566551-36567815, chr21-36568105-36568629, chr21-36570859-36571195, chr21-36573002-36573289, chr21-36575350-36575709, chr21-36576412-36577230, chr21-36583668-36584068, chr21-36584895-36585487, chr21-36585745-36586353, chr21-36587320-36592079, chr21-36592299-36593515, chr21-36594289-36594685, chr21-36597896-36598145,
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Co-expression with cohesin genes Rho = 0.1940
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information) - Tissue specificity
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Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.398
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60 -
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.880
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90 - Whether has cohesin-loop: True
- Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,MB157,DU145,K1,hTERT-HME1,H1-Mesenchymal,Olfactory,Hepatocyte-H9,MCF-7,GM12891,GM12878,K-562,A-549,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,NCI-H1437,iPSC,HCT-116,Hep-G2,HT-1197,H1-hESC,HT-1376,GM19238,Motor-Neuron,NaiveB,HUES64,SU-DHL-4,NPC-H9,RT-112,Skin-Fibroblast,HFF-hTERT,HAP1,MCF7-FASR
- Related loop: chr21:27500000-27525000~~chr21:36275000-36300000, chr21:34350000-34375000~~chr21:36225000-36250000, chr21:34350000-34375000~~chr21:36275000-36300000, chr21:36050000-36075000~~chr21:36200000-36225000, chr21:36075000-36100000~~chr21:36175000-36200000, chr21:36125000-36150000~~chr21:36225000-36250000, chr21:36140628-36142797~~chr21:36208896-36211059, chr21:36140770-36142598~~chr21:36208928-36210883, chr21:36140789-36142775~~chr21:36208898-36210957, chr21:36140792-36142611~~chr21:36208845-36210808, chr21:36140799-36142837~~chr21:36208339-36210839, chr21:36140808-36142792~~chr21:36208893-36211062, chr21:36140818-36142825~~chr21:36208180-36210735, chr21:36140822-36142823~~chr21:36208825-36210883, chr21:36140824-36142795~~chr21:36208849-36210862, chr21:36140828-36142593~~chr21:36208784-36210767, chr21:36140836-36142645~~chr21:36208979-36210847, chr21:36140837-36142525~~chr21:36208955-36210590, chr21:36140838-36142714~~chr21:36208696-36210781, chr21:36140838-36142786~~chr21:36208808-36211018, chr21:36140843-36142531~~chr21:36208942-36210568, chr21:36140848-36142815~~chr21:36208865-36210865, chr21:36140849-36142584~~chr21:36208920-36210789, chr21:36140850-36142837~~chr21:36208890-36210845, chr21:36140852-36142557~~chr21:36208778-36210979, chr21:36140862-36142780~~chr21:36208188-36210796, chr21:36140863-36142602~~chr21:36208770-36210834, chr21:36140866-36142633~~chr21:36208896-36210832, chr21:36140870-36142745~~chr21:36209005-36210744, chr21:36140871-36142703~~chr21:36208897-36210863, chr21:36150000-36175000~~chr21:36300000-36325000, chr21:36150000-36175000~~chr21:36325000-36350000, chr21:36150000-36175000~~chr21:36375000-36400000, chr21:36150000-36175000~~chr21:39175000-39200000, chr21:36150000-36175000~~chr21:46175000-46200000, chr21:36152011-36154258~~chr21:36208885-36210840, chr21:36152043-36154290~~chr21:36208880-36210854, chr21:36152093-36154114~~chr21:36208893-36211062, chr21:36152185-36154228~~chr21:36208896-36210870, chr21:36152191-36154260~~chr21:36208896-36210832, chr21:36152213-36154154~~chr21:36208928-36210883, chr21:36152221-36154080~~chr21:36208180-36210735, chr21:36152227-36154127~~chr21:36208825-36210883, chr21:36152242-36154206~~chr21:36208896-36211059, chr21:36152248-36154241~~chr21:36187568-36189319, chr21:36152248-36154241~~chr21:36208696-36210781, chr21:36152259-36154196~~chr21:36208897-36210863, chr21:36152272-36154246~~chr21:36208777-36210982, chr21:36152322-36154109~~chr21:36208843-36210788, chr21:36152382-36154180~~chr21:36208778-36210979, chr21:36152395-36154141~~chr21:36208770-36210834, chr21:36152396-36154049~~chr21:36208182-36211280, chr21:36152486-36154104~~chr21:36208903-36211039, chr21:36152494-36154153~~chr21:36208813-36210759, chr21:36152513-36154017~~chr21:36208784-36210767, chr21:36155171-36156841~~chr21:36208778-36210979, chr21:36155462-36156722~~chr21:36208903-36211039, chr21:36155654-36157667~~chr21:36208890-36210845, chr21:36155654-36157667~~chr21:36259462-36261497, chr21:36175000-36200000~~chr21:36350000-36375000, chr21:36175000-36200000~~chr21:36575000-36600000, chr21:36181050-36182274~~chr21:36329784-36332238, chr21:36187405-36189351~~chr21:36208897-36210863, chr21:36187568-36189319~~chr21:36208696-36210781, chr21:36200000-36225000~~chr21:36325000-36350000, chr21:36200000-36225000~~chr21:36350000-36375000, chr21:36200000-36225000~~chr21:36375000-36400000, chr21:36208725-36210834~~chr21:36329820-36331841, chr21:36208807-36210881~~chr21:36329776-36331875, chr21:36208849-36210862~~chr21:36329821-36332549, chr21:36208896-36211059~~chr21:36329784-36332238, chr21:36208955-36210590~~chr21:36330185-36331807, chr21:36209099-36210510~~chr21:36330219-36331784, chr21:36209109-36210630~~chr21:36330220-36331778, chr21:36209128-36210456~~chr21:36330409-36331736, chr21:36225000-36250000~~chr21:36325000-36350000, chr21:36245123-36246662~~chr21:36330384-36331754, chr21:36245246-36246544~~chr21:36329821-36332549, chr21:36250000-36275000~~chr21:36350000-36375000, chr21:36250000-36275000~~chr21:36375000-36400000, chr21:36250000-36275000~~chr21:36550000-36575000, chr21:36253261-36254421~~chr21:36319310-36321320, chr21:36259462-36261497~~chr21:36319312-36322600,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
Tools:
- Assay
