Deatailed information for gene ENSG00000156304
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009965
- Gene Symbol: SCAF4
- Ensembl ID: ENSG00000156304
-
Gene locus: chr21:31670999-31732118
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-31249931-31250684,
chr21-31251638-31252437,
chr21-31256576-31256637,
chr21-31257732-31258158,
chr21-31260562-31261769,
chr21-31264477-31265037,
chr21-31265345-31265885,
chr21-31266142-31267020,
chr21-31268211-31268470,
chr21-31273209-31273990,
chr21-31274283-31275119,
chr21-31373970-31375053,
chr21-31380139-31380510,
chr21-31381978-31382484,
chr21-31382914-31383204,
chr21-31385756-31388309,
chr21-31390976-31391592,
chr21-31392260-31393213,
chr21-31394630-31394826,
chr21-31395133-31395525,
chr21-31396580-31397002,
chr21-31397471-31398996,
chr21-31399268-31399467,
chr21-31623474-31624174,
chr21-31624761-31625676,
chr21-31666075-31666304,
chr21-31669061-31669469,
chr21-31671850-31672401,
chr21-31679593-31679852,
chr21-31681359-31681588,
chr21-31682687-31683516,
chr21-31685889-31686857,
chr21-31687804-31688047,
chr21-31690175-31690448,
chr21-31695434-31696225,
chr21-31705596-31706060,
chr21-31706429-31706648,
chr21-31707652-31707856,
chr21-31708059-31708349,
chr21-31710228-31711264,
chr21-31711898-31712847,
chr21-31713383-31713742,
chr21-31714124-31714482,
chr21-31716096-31716505,
chr21-31717839-31718283,
chr21-31719496-31719724,
chr21-31720387-31721045,
chr21-31722659-31722899,
chr21-31725854-31726651,
chr21-31727461-31727835,
chr21-31728911-31729266,
chr21-31729532-31733952,
chr21-31734532-31735896,
chr21-31737021-31738863,
chr21-31772220-31773460,
chr21-31774067-31774624,
chr21-31851015-31851259,
chr21-31851947-31852172,
chr21-31855210-31855593,
chr21-31857356-31857673,
chr21-31862100-31862414,
chr21-31863205-31863716,
chr21-31864316-31868880,
chr21-31869101-31869249,
chr21-31870626-31876394,
chr21-31949860-31950518,
chr21-31954932-31955194,
chr21-31968074-31968890,
chr21-31970770-31971371,
chr21-31973554-31973655,
chr21-31974576-31974810,
chr21-32248296-32250173,
chr21-32250431-32250902,
chr21-32252193-32252346,
chr21-32252822-32254394,
chr21-32255209-32255948,
chr21-32256207-32261140,
chr21-32263244-32263640,
chr21-32264631-32265932,
chr21-32266164-32267358,
chr21-32574949-32576472,
chr21-32576694-32579657,
chr21-32580005-32580573,
chr21-32580904-32582331,
chr21-32583026-32584806,
chr21-32585090-32585613,
chr21-32586300-32587559,
chr21-32590405-32590668,
chr21-32590870-32591197,
chr21-32592176-32593983,
chr21-32594251-32594977,
chr21-32595506-32596052,
chr21-32596424-32597923,
chr21-32598775-32602954,
chr21-32603193-32603581,
chr21-32604431-32605130,
chr21-32610128-32610562,
chr21-32610963-32613801,
chr21-32614942-32615265,
chr21-32618034-32618378,
chr21-32618831-32619540,
chr21-32620088-32620453,
chr21-32621102-32621530,
chr21-32624498-32625154,
chr21-32726512-32729587,
chr21-32732552-32732879,
chr21-32753932-32754480,
chr21-32757827-32758170,
chr21-32760835-32760984,
chr21-32769734-32773333,
-
Co-expression with cohesin genes Rho = 0.6347
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.274
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.898
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: HEK293T,GM12878,CyT49-endoderm,Hep-G2,IMR-90,K-562,H1-hESC,HFF-hTERT,HAP1,HFFc6,MSLCL,HeLa-S3,SU-DHL-2,H9-hESC,H1-Mesenchymal,SU-DHL-4
- Related loop:
chr21:27500000-27525000~~chr21:31650000-31675000,
chr21:29025000-29050000~~chr21:31675000-31700000,
chr21:29050000-29075000~~chr21:31675000-31700000,
chr21:31250000-31275000~~chr21:31700000-31725000,
chr21:31250000-31275000~~chr21:31725000-31750000,
chr21:31375000-31400000~~chr21:31700000-31725000,
chr21:31622539-31624965~~chr21:31682614-31683831,
chr21:31622573-31624872~~chr21:31665039-31666300,
chr21:31622928-31624476~~chr21:31665036-31666246,
chr21:31650000-31675000~~chr21:39175000-39200000,
chr21:31675000-31700000~~chr21:32725000-32750000,
chr21:31675000-31700000~~chr21:32750000-32775000,
chr21:31675000-31700000~~chr21:39175000-39200000,
chr21:31700000-31725000~~chr21:32600000-32625000,
chr21:31725000-31750000~~chr21:31850000-31875000,
chr21:31725000-31750000~~chr21:31950000-31975000,
chr21:31725000-31750000~~chr21:32250000-32275000,
chr21:31725000-31750000~~chr21:32575000-32600000,
chr21:31725000-31750000~~chr21:32600000-32625000,
chr21:31725000-31750000~~chr21:32750000-32775000,
chr21:31725000-31750000~~chr21:36975000-37000000,
chr21:31730164-31731503~~chr21:31771972-31774192,
chr21:31731849-31734483~~chr21:31771972-31774192,
chr21:31732064-31733263~~chr21:31771956-31774066,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFI8649RQJ, 4DNFIQYQWPF5, GSE95015, ENCSR194SRI, 4DNFIMROE6N4, 4DNFI5SUHCGZ, ENCSR852KQC, 4DNFI7H4II2V, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIBM714BP, 4DNFII6AN691, 4DNFIYD8LO9Z, 4DNFICSTCJQZ, ENCSR981FNA, 4DNFIIMZB6Y9, ENCSR452NHL, 4DNFI1E6NJQJ, ENCSR128RPG, GSE52457, 4DNFI3A3VYWU, ENCSR658RQQ, 4DNFIM2BMJ33, Direct, 4DNFI6XD6JAQ, 4DNFIYDBBSE3, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, 4DNFIK61ILGM, GSE44267, 4DNFIPAF4PYT, 4DNFIDKJFK2S, 4DNFIFLJLIS5, GSE105028, 4DNFIDZT7PR8, 4DNFII84FBKM
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: K-562,SLK,HeLa-S3,P3HR-1
- Cohesin-DEGs, number of studies: 4
- Cohesin-DEGs, study: GSE140651,GSE138937,GSE131448,GSE130558
- Cohesin-DEGs, subunit: WAPL,CTCF,SMC1,SA2