Deatailed information for gene ENSG00000157554
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010109
- Gene Symbol: ERG
- Ensembl ID: ENSG00000157554
-
Gene locus: chr21:38380029-38661780
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-37729837-37730152,
chr21-37730892-37731148,
chr21-37735375-37735832,
chr21-37742634-37743029,
chr21-37746968-37747115,
chr21-37749181-37749550,
chr21-37801202-37801706,
chr21-37803574-37804429,
chr21-37807801-37808056,
chr21-37811683-37812097,
chr21-37815691-37816880,
chr21-37817250-37818781,
chr21-37821953-37822520,
chr21-37823026-37823235,
chr21-37930941-37931013,
chr21-37939152-37939573,
chr21-37943352-37943708,
chr21-37944394-37945141,
chr21-37947164-37947554,
chr21-37949071-37949548,
chr21-38052709-38053305,
chr21-38059512-38059763,
chr21-38075842-38076104,
chr21-38077039-38077371,
chr21-38077679-38077885,
chr21-38078126-38079068,
chr21-38080896-38081400,
chr21-38083087-38083355,
chr21-38089024-38089496,
chr21-38091949-38092674,
chr21-38095290-38095530,
chr21-38151064-38151512,
chr21-38155827-38157030,
chr21-38157453-38161826,
chr21-38165622-38167121,
chr21-38167829-38173299,
chr21-38173632-38174464,
chr21-38348297-38360784,
chr21-38362993-38363357,
chr21-38365365-38365661,
chr21-38375250-38375602,
chr21-38376290-38378168,
chr21-38379785-38381250,
chr21-38383484-38384452,
chr21-38384798-38385015,
chr21-38387044-38387525,
chr21-38388662-38389604,
chr21-38390009-38390598,
chr21-38394330-38394741,
chr21-38402377-38402598,
chr21-38403268-38403875,
chr21-38404289-38404685,
chr21-38405440-38406157,
chr21-38409166-38409696,
chr21-38411151-38411665,
chr21-38413939-38415446,
chr21-38417471-38417757,
chr21-38418681-38418947,
chr21-38420276-38420341,
chr21-38423063-38423584,
chr21-38424139-38424811,
chr21-38426642-38427303,
chr21-38429372-38429658,
chr21-38434434-38435810,
chr21-38436999-38437515,
chr21-38438184-38443584,
chr21-38444745-38445563,
chr21-38448308-38449238,
chr21-38455300-38455999,
chr21-38457118-38460911,
chr21-38467806-38468347,
chr21-38468617-38469501,
chr21-38470589-38471230,
chr21-38472610-38473236,
chr21-38473884-38475107,
chr21-38475558-38475868,
chr21-38476117-38476979,
chr21-38477310-38477577,
chr21-38478606-38479246,
chr21-38479953-38480442,
chr21-38483538-38484977,
chr21-38485444-38487130,
chr21-38487957-38489481,
chr21-38489687-38490173,
chr21-38490421-38491046,
chr21-38491594-38492338,
chr21-38493489-38495573,
chr21-38496136-38496508,
chr21-38498193-38500425,
chr21-38501041-38501534,
chr21-38503073-38508323,
chr21-38509890-38510117,
chr21-38510943-38512229,
chr21-38512754-38513121,
chr21-38519985-38520039,
chr21-38520552-38520872,
chr21-38524127-38524519,
chr21-38524820-38525118,
chr21-38525327-38525704,
chr21-38528423-38528734,
chr21-38531264-38531985,
chr21-38544663-38545173,
chr21-38548479-38549133,
chr21-38559722-38560016,
chr21-38560323-38560581,
chr21-38560926-38562459,
chr21-38566830-38568175,
chr21-38568732-38569349,
chr21-38572074-38572357,
chr21-38576611-38576930,
chr21-38577420-38578130,
chr21-38579596-38580252,
chr21-38581777-38582078,
chr21-38587293-38587727,
chr21-38591359-38594057,
chr21-38596343-38596638,
chr21-38597537-38597765,
chr21-38599047-38599490,
chr21-38601403-38601985,
chr21-38603967-38604329,
chr21-38607310-38607614,
chr21-38610373-38611557,
chr21-38612552-38615670,
chr21-38619808-38623357,
chr21-38624029-38624660,
chr21-38628419-38628858,
chr21-38631075-38632314,
chr21-38636057-38637522,
chr21-38638948-38639389,
chr21-38639807-38640047,
chr21-38644766-38647197,
chr21-38649184-38649471,
chr21-38655893-38656196,
chr21-38659292-38662622,
chr21-38664405-38665212,
chr21-38666630-38671138,
chr21-38675277-38675639,
chr21-38677433-38677813,
chr21-38678221-38680810,
chr21-38683388-38683795,
chr21-38692357-38692840,
chr21-38693068-38693253,
chr21-38696633-38696955,
chr21-38698999-38699651,
chr21-38700535-38701065,
chr21-38701561-38701796,
chr21-38702989-38703239,
chr21-38703807-38703915,
chr21-38707733-38707894,
chr21-38709620-38709912,
chr21-38710302-38714342,
chr21-38714859-38715706,
chr21-38717916-38718385,
chr21-38719363-38719850,
chr21-38722023-38723084,
chr21-38724534-38724638,
chr21-38750928-38753320,
chr21-38755256-38758111,
chr21-38758589-38759179,
chr21-38759468-38760630,
chr21-38761727-38762289,
chr21-38762803-38763102,
chr21-38764079-38764735,
chr21-38765117-38765356,
chr21-38766557-38767917,
chr21-38768383-38770086,
chr21-38771502-38771829,
chr21-38772380-38772727,
chr21-38772940-38775249,
chr21-38800466-38816528,
chr21-38816889-38818881,
chr21-38819201-38823342,
chr21-38823665-38827360,
chr21-38849471-38854263,
chr21-38856453-38857719,
chr21-38858525-38859524,
chr21-38859766-38860539,
chr21-38861132-38861513,
chr21-38862000-38863279,
chr21-38864066-38864405,
chr21-38867234-38867512,
chr21-38869262-38870389,
chr21-38872690-38873110,
chr21-38873491-38873832,
chr21-38874324-38875151,
chr21-38875623-38877038,
chr21-38878486-38879325,
chr21-38879734-38880718,
chr21-38881074-38881602,
chr21-38887207-38887702,
chr21-38888790-38889935,
chr21-38894935-38895727,
chr21-38897435-38899519,
chr21-38902877-38915813,
chr21-38916103-38918039,
chr21-38918470-38919889,
chr21-38920487-38927328,
chr21-38927606-38928109,
chr21-38929045-38929452,
chr21-38930541-38932324,
chr21-38933315-38934329,
chr21-38934867-38935136,
chr21-38936897-38937530,
chr21-38937871-38939705,
chr21-38940267-38940553,
chr21-38942437-38943594,
chr21-38943990-38947249,
chr21-38947518-38949339,
chr21-38950281-38951853,
chr21-38954547-38956486,
chr21-38956696-38961906,
chr21-38962289-38962670,
chr21-38963077-38964501,
chr21-38964963-38966859,
chr21-38967409-38967759,
chr21-38968672-38969620,
chr21-38970013-38971411,
chr21-38971768-38972717,
chr21-38973691-38974043,
chr21-38999239-39001723,
chr21-39002157-39005860,
chr21-39006216-39008144,
chr21-39009600-39010167,
chr21-39010386-39017610,
chr21-39018454-39019370,
chr21-39019594-39020196,
chr21-39020597-39024249,
chr21-39024973-39026738,
chr21-39050368-39052319,
chr21-39052765-39053562,
chr21-39054530-39055364,
chr21-39057866-39058125,
chr21-39058790-39059170,
chr21-39060621-39063414,
chr21-39065855-39066363,
chr21-39066759-39067914,
chr21-39071535-39072229,
chr21-39099515-39100049,
chr21-39102151-39102227,
chr21-39103549-39109094,
chr21-39113959-39114286,
chr21-39114686-39116256,
chr21-39116710-39117795,
chr21-39118015-39120208,
chr21-39120833-39129703,
chr21-39132355-39132622,
chr21-39133040-39133962,
chr21-39134166-39141978,
chr21-39151590-39151880,
chr21-39153009-39153827,
chr21-39156042-39156407,
chr21-39156653-39158153,
chr21-39158424-39158895,
chr21-39159537-39161498,
chr21-39171426-39171861,
chr21-39172222-39172621,
chr21-39173429-39176751,
chr21-39178845-39179222,
chr21-39180628-39180930,
chr21-39181962-39185522,
chr21-39189884-39190456,
chr21-39377536-39378376,
chr21-39378615-39382320,
chr21-39383016-39384062,
chr21-39384730-39386685,
chr21-39386888-39390967,
chr21-39395561-39395853,
chr21-39396172-39397021,
chr21-39398076-39398420,
chr21-39398702-39399019,
chr21-39440305-39444075,
chr21-39451104-39454021,
chr21-39455324-39455823,
chr21-39456702-39457849,
chr21-39461514-39462016,
chr21-39601006-39602588,
chr21-39604265-39605410,
chr21-39607665-39608007,
chr21-39608787-39609235,
chr21-39609628-39615120,
chr21-39616321-39616816,
-
Co-expression with cohesin genes Rho = 0.3315
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.548
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.899
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,TAMR-MCF7,Keratinocytes192627,Aorta,GM12892,K1,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,MCF-7,HEK293T,GM12891,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,NCI-H1437,iPSC,ARPE-19,HCT-116,OCI-AML-3,Hep-G2,HT-1197,Kelly,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,U-937,BMEC,SU-DHL-4,HUVEC,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Left-Ventricle,KBM-7,Jurkat,CC-2551,CyT49-Gut,HAP1,HFF-hTERT,MCF7-FASR
- Related loop:
chr21:37725000-37750000~~chr21:38375000-38400000,
chr21:37800000-37825000~~chr21:38650000-38675000,
chr21:37925000-37950000~~chr21:38525000-38550000,
chr21:38050000-38075000~~chr21:38375000-38400000,
chr21:38050000-38075000~~chr21:38575000-38600000,
chr21:38050000-38075000~~chr21:38650000-38675000,
chr21:38075000-38100000~~chr21:38525000-38550000,
chr21:38150000-38175000~~chr21:38450000-38475000,
chr21:38150000-38175000~~chr21:38475000-38500000,
chr21:38150000-38175000~~chr21:38500000-38525000,
chr21:38150000-38175000~~chr21:38525000-38550000,
chr21:38150000-38175000~~chr21:38575000-38600000,
chr21:38350000-38375000~~chr21:38575000-38600000,
chr21:38375000-38400000~~chr21:38500000-38525000,
chr21:38375000-38400000~~chr21:38525000-38550000,
chr21:38375000-38400000~~chr21:38575000-38600000,
chr21:38375000-38400000~~chr21:38625000-38650000,
chr21:38375000-38400000~~chr21:38650000-38675000,
chr21:38375000-38400000~~chr21:38675000-38700000,
chr21:38375000-38400000~~chr21:38700000-38725000,
chr21:38375000-38400000~~chr21:39100000-39125000,
chr21:38375000-38400000~~chr21:39125000-39150000,
chr21:38375000-38400000~~chr21:39150000-39175000,
chr21:38375000-38400000~~chr21:39600000-39625000,
chr21:38379619-38381509~~chr21:39174528-39176139,
chr21:38379946-38381381~~chr21:39152646-39154555,
chr21:38379963-38381222~~chr21:39137274-39139116,
chr21:38388533-38390282~~chr21:39174059-39176516,
chr21:38400000-38425000~~chr21:38575000-38600000,
chr21:38425000-38450000~~chr21:38700000-38725000,
chr21:38450000-38475000~~chr21:38700000-38725000,
chr21:38450000-38475000~~chr21:38900000-38925000,
chr21:38450000-38475000~~chr21:39000000-39025000,
chr21:38450000-38475000~~chr21:39100000-39125000,
chr21:38450000-38475000~~chr21:39125000-39150000,
chr21:38475000-38500000~~chr21:38675000-38700000,
chr21:38475000-38500000~~chr21:38875000-38900000,
chr21:38475000-38500000~~chr21:39125000-39150000,
chr21:38475000-38500000~~chr21:39150000-39175000,
chr21:38475839-38477375~~chr21:39125156-39127107,
chr21:38494233-38495488~~chr21:39174059-39176516,
chr21:38498759-38500180~~chr21:39125156-39127107,
chr21:38500000-38525000~~chr21:38625000-38650000,
chr21:38500000-38525000~~chr21:38650000-38675000,
chr21:38500000-38525000~~chr21:38675000-38700000,
chr21:38500000-38525000~~chr21:38700000-38725000,
chr21:38500000-38525000~~chr21:38750000-38775000,
chr21:38500000-38525000~~chr21:38800000-38825000,
chr21:38500000-38525000~~chr21:38850000-38875000,
chr21:38500000-38525000~~chr21:38900000-38925000,
chr21:38500000-38525000~~chr21:39100000-39125000,
chr21:38500000-38525000~~chr21:39125000-39150000,
chr21:38500000-38525000~~chr21:39150000-39175000,
chr21:38500000-38525000~~chr21:39175000-39200000,
chr21:38500000-38525000~~chr21:39375000-39400000,
chr21:38504651-38506971~~chr21:39137271-39139180,
chr21:38504657-38506967~~chr21:38711299-38713234,
chr21:38504659-38506970~~chr21:38711337-38713456,
chr21:38504659-38506970~~chr21:39135752-39139340,
chr21:38504661-38506972~~chr21:39135752-39139234,
chr21:38504661-38506972~~chr21:39174299-39176494,
chr21:38504682-38506897~~chr21:38711342-38713466,
chr21:38504693-38507356~~chr21:38711365-38713290,
chr21:38504693-38507356~~chr21:39135757-39139176,
chr21:38504693-38507356~~chr21:39174059-39176516,
chr21:38504694-38507025~~chr21:39135761-39139165,
chr21:38504694-38507025~~chr21:39174543-39176122,
chr21:38504699-38507035~~chr21:39136221-39139367,
chr21:38504701-38506502~~chr21:39135777-39139304,
chr21:38504701-38506502~~chr21:39152806-39154190,
chr21:38504704-38506958~~chr21:39125124-39127062,
chr21:38504704-38506958~~chr21:39135757-39139157,
chr21:38504708-38507639~~chr21:39135753-39139144,
chr21:38504709-38506958~~chr21:38711358-38713304,
chr21:38504709-38506958~~chr21:39136233-39139143,
chr21:38504715-38506948~~chr21:39125188-39128467,
chr21:38504715-38506948~~chr21:39136158-39139240,
chr21:38504715-38507432~~chr21:39137265-39139144,
chr21:38504722-38507046~~chr21:39135777-39139215,
chr21:38504723-38507444~~chr21:39135766-39139156,
chr21:38504725-38506920~~chr21:39136965-39139305,
chr21:38504729-38506966~~chr21:39136708-39139166,
chr21:38504735-38506980~~chr21:39135742-39136980,
chr21:38504738-38506474~~chr21:39137262-39139083,
chr21:38504739-38507562~~chr21:39137207-39139175,
chr21:38504739-38507562~~chr21:39440834-39442538,
chr21:38504745-38506938~~chr21:39136790-39139170,
chr21:38504745-38506938~~chr21:39174194-39176266,
chr21:38504757-38506917~~chr21:38711337-38713109,
chr21:38504783-38506832~~chr21:39135735-39136956,
chr21:38504783-38506832~~chr21:39137550-39139120,
chr21:38504824-38507757~~chr21:39135757-39139204,
chr21:38504928-38507061~~chr21:39125201-39127072,
chr21:38504928-38507061~~chr21:39135759-39139198,
chr21:38504928-38507061~~chr21:39152794-39154209,
chr21:38504928-38507061~~chr21:39174538-39176142,
chr21:38505033-38506464~~chr21:39136191-39139182,
chr21:38505044-38506990~~chr21:38711624-38712942,
chr21:38505044-38506990~~chr21:39135737-39136964,
chr21:38505069-38506955~~chr21:38711492-38712926,
chr21:38505086-38506468~~chr21:39136216-39139158,
chr21:38505090-38506554~~chr21:38711400-38712971,
chr21:38505153-38506875~~chr21:39125458-39126872,
chr21:38505153-38506875~~chr21:39135794-39136979,
chr21:38505153-38506875~~chr21:39137264-39139102,
chr21:38505153-38506875~~chr21:39174680-39176016,
chr21:38505190-38506606~~chr21:39136767-39139174,
chr21:38505221-38506513~~chr21:39137257-39139089,
chr21:38511147-38512755~~chr21:39136825-39139305,
chr21:38511187-38512681~~chr21:39136158-39139240,
chr21:38511190-38512744~~chr21:39135761-39139165,
chr21:38511252-38512555~~chr21:39135781-39139348,
chr21:38511272-38512659~~chr21:38711443-38713180,
chr21:38525000-38550000~~chr21:38625000-38650000,
chr21:38525000-38550000~~chr21:38700000-38725000,
chr21:38525000-38550000~~chr21:38850000-38875000,
chr21:38525000-38550000~~chr21:38875000-38900000,
chr21:38525000-38550000~~chr21:38950000-38975000,
chr21:38525000-38550000~~chr21:39050000-39075000,
chr21:38525000-38550000~~chr21:39100000-39125000,
chr21:38525000-38550000~~chr21:39125000-39150000,
chr21:38525000-38550000~~chr21:39150000-39175000,
chr21:38525000-38550000~~chr21:39450000-39475000,
chr21:38525000-38550000~~chr21:39600000-39625000,
chr21:38575000-38600000~~chr21:38675000-38700000,
chr21:38575000-38600000~~chr21:38850000-38875000,
chr21:38575000-38600000~~chr21:38925000-38950000,
chr21:38575000-38600000~~chr21:39000000-39025000,
chr21:38575000-38600000~~chr21:39375000-39400000,
chr21:38600000-38625000~~chr21:38700000-38725000,
chr21:38620584-38622050~~chr21:38711370-38712948,
chr21:38620685-38621928~~chr21:39137249-39139154,
chr21:38625000-38650000~~chr21:39600000-39625000,
chr21:38650000-38675000~~chr21:38750000-38775000,
chr21:38650000-38675000~~chr21:38800000-38825000,
chr21:38650000-38675000~~chr21:39000000-39025000,
chr21:38650000-38675000~~chr21:39125000-39150000,
chr21:38650000-38675000~~chr21:39150000-39175000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE43070, 4DNFIDJ2JZ7Q, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, ENCSR361AYD, GSE103148, 4DNFI7H4II2V, 4DNFIZ4F74QR, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFI9VXTBE2, GSE99541, ENCSR668RDP, 4DNFICEGAHRC, 4DNFIE8T8JZ8, ENCSR658RQQ, ENCSR299VMZ, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, GSE116872, ENCSR305RTT, ENCSR000FDB, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, ENCSR033GUP, 4DNFIQWD8ZYD, 4DNFI3CFMRID, ENCSR662QKG, 4DNFIW22BNB5, GSE94872, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, ENCSR146FPM, ENCSR478BMT, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE52457, Direct, ENCSR314HAC, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIH7TH4MF, 4DNFIT96Z365, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIE8E4ANZ, GSE120294, 4DNFIW8TIFI5, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIFHU75I5, 4DNFIYD8LO9Z, ENCSR123UVP, 4DNFIL9M97T2, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIM2BMJ33, GSE165038, 4DNFIALNLR78, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, ENCSR094EIC, GSE58752, ENCSR507AHE, 4DNFI8649RQJ, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, 4DNFI6EIFUZI, 4DNFII6AN691, GSE111537, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, ENCSR128RPG, 4DNFISTWNV9C, GSE101921, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFIP71EWXC, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: Fibroblast,CordBlood,K-562
- Cohesin-DEGs, number of studies: 4
- Cohesin-DEGs, study: GSE73224,GSE131448,SRP050576
- Cohesin-DEGs, subunit: CdLS,SMC1,Rad21,SA2