Deatailed information for gene ENSG00000157557
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010110
- Gene Symbol: ETS2
- Ensembl ID: ENSG00000157557
-
Gene locus: chr21:38805182-38824955
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-37848590-37851352,
chr21-37851997-37852496,
chr21-37854587-37856602,
chr21-37858133-37858424,
chr21-37862475-37863023,
chr21-37863574-37864405,
chr21-37865357-37865570,
chr21-37865868-37866779,
chr21-37868675-37872241,
chr21-37873511-37874441,
chr21-37874747-37875524,
chr21-38151064-38151512,
chr21-38155827-38157030,
chr21-38157453-38161826,
chr21-38165622-38167121,
chr21-38167829-38173299,
chr21-38173632-38174464,
chr21-38498193-38500425,
chr21-38501041-38501534,
chr21-38503073-38508323,
chr21-38509890-38510117,
chr21-38510943-38512229,
chr21-38512754-38513121,
chr21-38519985-38520039,
chr21-38520552-38520872,
chr21-38524127-38524519,
chr21-38524820-38525118,
chr21-38655893-38656196,
chr21-38659292-38662622,
chr21-38664405-38665212,
chr21-38666630-38671138,
chr21-38729814-38737491,
chr21-38800466-38816528,
chr21-38816889-38818881,
chr21-38819201-38823342,
chr21-38823665-38827360,
chr21-38828874-38829129,
chr21-38902877-38915813,
chr21-38916103-38918039,
chr21-38918470-38919889,
chr21-38920487-38927328,
chr21-38950281-38951853,
chr21-38954547-38956486,
chr21-38956696-38961906,
chr21-38962289-38962670,
chr21-38963077-38964501,
chr21-38964963-38966859,
chr21-38967409-38967759,
chr21-38968672-38969620,
chr21-38970013-38971411,
chr21-38971768-38972717,
chr21-38973691-38974043,
chr21-38976614-38977242,
chr21-38979219-38983585,
chr21-38983801-38991057,
chr21-38991357-38996105,
chr21-38997973-38998636,
chr21-38999239-39001723,
chr21-39002157-39005860,
chr21-39006216-39008144,
chr21-39009600-39010167,
chr21-39010386-39017610,
chr21-39018454-39019370,
chr21-39019594-39020196,
chr21-39020597-39024249,
chr21-39024973-39026738,
chr21-39027861-39028086,
chr21-39028294-39030869,
chr21-39031159-39032411,
chr21-39033437-39035154,
chr21-39035632-39038463,
chr21-39038968-39039720,
chr21-39040336-39041026,
chr21-39041745-39042186,
chr21-39043133-39043267,
chr21-39045369-39046036,
chr21-39046431-39047128,
chr21-39047690-39048980,
chr21-39049295-39049766,
chr21-39050368-39052319,
chr21-39052765-39053562,
chr21-39054530-39055364,
chr21-39057866-39058125,
chr21-39058790-39059170,
chr21-39060621-39063414,
chr21-39065855-39066363,
chr21-39066759-39067914,
chr21-39071535-39072229,
chr21-39077469-39078690,
chr21-39079018-39081868,
chr21-39082316-39090007,
chr21-39090288-39091651,
chr21-39091863-39092124,
chr21-39092794-39099185,
chr21-39099515-39100049,
chr21-39102151-39102227,
chr21-39103549-39109094,
chr21-39113959-39114286,
chr21-39114686-39116256,
chr21-39116710-39117795,
chr21-39118015-39120208,
chr21-39120833-39129703,
chr21-39132355-39132622,
chr21-39133040-39133962,
chr21-39134166-39141978,
chr21-39173429-39176751,
chr21-39178845-39179222,
chr21-39180628-39180930,
chr21-39181962-39185522,
chr21-39189884-39190456,
chr21-39326856-39327201,
chr21-39328143-39328508,
chr21-39329775-39330179,
chr21-39330451-39330860,
chr21-39332176-39332684,
chr21-39333291-39334572,
chr21-39335104-39335948,
chr21-39336590-39337662,
chr21-39338003-39338994,
chr21-39339920-39340238,
chr21-39342069-39342466,
chr21-39343271-39343467,
chr21-39343962-39344240,
chr21-39344676-39351972,
chr21-39377536-39378376,
chr21-39378615-39382320,
chr21-39383016-39384062,
chr21-39384730-39386685,
chr21-39386888-39390967,
chr21-39395561-39395853,
chr21-39396172-39397021,
chr21-39398076-39398420,
chr21-39398702-39399019,
chr21-39425591-39426058,
chr21-39427352-39427664,
chr21-39430503-39430780,
chr21-39431574-39431827,
chr21-39435612-39435881,
chr21-39436505-39436763,
chr21-39440305-39444075,
chr21-39444581-39446444,
chr21-39447001-39447710,
chr21-39601006-39602588,
chr21-39604265-39605410,
chr21-39607665-39608007,
chr21-39608787-39609235,
chr21-39609628-39615120,
chr21-39616321-39616816,
-
Co-expression with cohesin genes Rho = 0.1813
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.422
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.843
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,TAMR-MCF7,DU145,Aorta,K1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,MCF-7,HEK293T,SARS-Cov2-olfactory,A-549,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,iPSC,Liver,ARPE-19,HT-1197,H1-hESC,HT-1376,GM19238,Bladder,SU-DHL-4,NPC-H9,RT-112,Skin-Fibroblast,CC-2551,HFF-hTERT,HAP1,MCF7-FASR
- Related loop:
chr21:37850000-37875000~~chr21:38800000-38825000,
chr21:38150000-38175000~~chr21:38800000-38825000,
chr21:38500000-38525000~~chr21:38800000-38825000,
chr21:38650000-38675000~~chr21:38800000-38825000,
chr21:38732707-38735284~~chr21:38804228-38806108,
chr21:38732781-38735273~~chr21:38804159-38806607,
chr21:38733127-38735189~~chr21:38804397-38807388,
chr21:38733295-38735171~~chr21:38804079-38807181,
chr21:38733315-38735206~~chr21:38804450-38807728,
chr21:38800000-38825000~~chr21:38900000-38925000,
chr21:38800000-38825000~~chr21:38950000-38975000,
chr21:38800000-38825000~~chr21:38975000-39000000,
chr21:38800000-38825000~~chr21:39000000-39025000,
chr21:38800000-38825000~~chr21:39025000-39050000,
chr21:38800000-38825000~~chr21:39050000-39075000,
chr21:38800000-38825000~~chr21:39075000-39100000,
chr21:38800000-38825000~~chr21:39100000-39125000,
chr21:38800000-38825000~~chr21:39125000-39150000,
chr21:38800000-38825000~~chr21:39175000-39200000,
chr21:38800000-38825000~~chr21:39325000-39350000,
chr21:38800000-38825000~~chr21:39375000-39400000,
chr21:38800000-38825000~~chr21:39425000-39450000,
chr21:38800000-38825000~~chr21:39600000-39625000,
chr21:38803978-38806088~~chr21:39125286-39127099,
chr21:38804025-38807695~~chr21:39125068-39127102,
chr21:38804025-38807695~~chr21:39135752-39139340,
chr21:38804026-38806194~~chr21:39120537-39121759,
chr21:38804026-38806194~~chr21:39125246-39127033,
chr21:38804026-38806194~~chr21:39135746-39136928,
chr21:38804026-38806194~~chr21:39137271-39139180,
chr21:38804033-38807696~~chr21:39124252-39127148,
chr21:38804033-38807696~~chr21:39136199-39139181,
chr21:38804038-38807501~~chr21:39135777-39139304,
chr21:38804047-38805972~~chr21:39125144-39128433,
chr21:38804058-38806494~~chr21:39125159-39127061,
chr21:38804079-38807181~~chr21:39125184-39128368,
chr21:38804079-38807181~~chr21:39137214-39139028,
chr21:38804094-38806437~~chr21:39120295-39121683,
chr21:38804094-38806437~~chr21:39125164-39127080,
chr21:38804103-38806461~~chr21:39125098-39127101,
chr21:38804103-38806461~~chr21:39135752-39139234,
chr21:38804112-38806553~~chr21:39125142-39127123,
chr21:38804112-38806553~~chr21:39136790-39139170,
chr21:38804130-38806749~~chr21:39135757-39139157,
chr21:38804148-38807306~~chr21:39011954-39013137,
chr21:38804148-38807306~~chr21:39022163-39023870,
chr21:38804148-38807306~~chr21:39037089-39038810,
chr21:38804148-38807306~~chr21:39086131-39087401,
chr21:38804148-38807306~~chr21:39125161-39127119,
chr21:38804148-38807306~~chr21:39135763-39136936,
chr21:38804148-38807306~~chr21:39136965-39139305,
chr21:38804159-38806544~~chr21:39120293-39121764,
chr21:38804159-38806544~~chr21:39125151-39127099,
chr21:38804159-38806607~~chr21:39125163-39127081,
chr21:38804213-38806093~~chr21:39065920-39068738,
chr21:38804213-38806093~~chr21:39125156-39127107,
chr21:38804213-38806093~~chr21:39135757-39139176,
chr21:38804263-38806143~~chr21:39135761-39139165,
chr21:38804345-38806440~~chr21:39125177-39127057,
chr21:38804397-38807388~~chr21:39020330-39024316,
chr21:38804397-38807388~~chr21:39125161-39127067,
chr21:38804397-38807388~~chr21:39136216-39139158,
chr21:38804450-38807728~~chr21:39136191-39139182,
chr21:38804458-38807167~~chr21:39125310-39127084,
chr21:38804482-38806565~~chr21:39136279-39139355,
chr21:38804598-38805801~~chr21:39086120-39087303,
chr21:38810787-38812114~~chr21:39125156-39127107,
chr21:38810787-38812114~~chr21:39174059-39176516,
chr21:38818748-38820756~~chr21:39047115-39049516,
chr21:38818748-38820756~~chr21:39125161-39127067,
chr21:38818748-38820756~~chr21:39136216-39139158,
chr21:38823242-38824815~~chr21:39125156-39127107,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFI8649RQJ, GSE87112, 4DNFI3CFMRID, ENCSR662QKG, GSE95015, GSE43070, 4DNFIMROE6N4, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, GSE108787, 4DNFI5SUHCGZ, GSE120294, ENCSR672RHL, 4DNFIILDWK8M, 4DNFI7H4II2V, 4DNFIZ4F74QR, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFI6EIFUZI, 4DNFIBM714BP, ENCSR113OIR, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, ENCSR668RDP, ENCSR381DCY, GSE155380, ENCSR587DSF, 4DNFICEGAHRC, 4DNFIIMZB6Y9, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, ENCSR128RPG, 4DNFIOUSETUP, GSE52457, 4DNFI3A3VYWU, 4DNFIJ7OAIFQ, ENCSR658RQQ, 4DNFIM2BMJ33, Direct, ENCSR314HAC, 4DNFIAS8LV1C, 4DNFIBY3UHJB, ENCSR386KHY, 4DNFI6JJQKFJ, 4DNFIX7H3CE2, 4DNFIK61ILGM, GSE108869, ENCSR244BBG, ENCSR393LOP, GSE44267, 4DNFIC3HAU11, ENCSR255XYX, ENCSR404HWQ, ENCSR247RGI, ENCSR110JOO, 4DNFI5LCW273, 4DNFIE5TEYK7, ENCSR527RXH, ENCSR933UZH, GSE105028, 4DNFIS5F6EBL, GSE58752, 4DNFIBKZK63V, 4DNFIH7TH4MF, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: OCI-AML-3,P3HR-1,K-562,MCF-10A,CMK,U2OS,HeLa-S3,CordBlood
- Cohesin-DEGs, number of studies: 8
- Cohesin-DEGs, study: GSE73224,GSE111537,GSE140651,GSE101921,GSE154086,GSE131448,GSE89799,GSE130558
- Cohesin-DEGs, subunit: WAPL,Rad21,SA2,SMC1