Deatailed information for gene ENSG00000159055
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010284
- Gene Symbol: MIS18A
- Ensembl ID: ENSG00000159055
-
Gene locus: chr21:32268227-32279049
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-31096520-31101905,
chr21-31103314-31103877,
chr21-31106786-31110561,
chr21-31112340-31112482,
chr21-31115256-31115414,
chr21-31116488-31118341,
chr21-31120255-31120833,
chr21-31123859-31124581,
chr21-31125565-31125905,
chr21-31132822-31133809,
chr21-31136782-31137273,
chr21-31141215-31142096,
chr21-31142431-31143315,
chr21-31143850-31144571,
chr21-31144999-31145312,
chr21-31146265-31147154,
chr21-31151663-31152151,
chr21-31155559-31155820,
chr21-31159176-31159441,
chr21-31160575-31161697,
chr21-31162086-31162400,
chr21-31162855-31163109,
chr21-31164095-31164388,
chr21-31172023-31172627,
chr21-31173153-31175305,
chr21-31175520-31176738,
chr21-31177211-31177721,
chr21-31177999-31183023,
chr21-31183657-31184957,
chr21-31185387-31185986,
chr21-31188916-31189109,
chr21-31194439-31202575,
chr21-31203109-31204027,
chr21-31212597-31212933,
chr21-31213155-31214950,
chr21-31215238-31215447,
chr21-31215856-31216097,
chr21-31216371-31217225,
chr21-31218747-31219814,
chr21-31220481-31221467,
chr21-31222011-31222540,
chr21-31725854-31726651,
chr21-31727461-31727835,
chr21-31728911-31729266,
chr21-31729532-31733952,
chr21-31734532-31735896,
chr21-31737021-31738863,
chr21-31739215-31739559,
chr21-31744136-31744783,
chr21-31745048-31745345,
chr21-31749551-31751240,
chr21-31752382-31752744,
chr21-31753017-31753300,
chr21-31756290-31756665,
chr21-31757643-31758184,
chr21-31759524-31759803,
chr21-31761057-31761442,
chr21-31766028-31766595,
chr21-31769626-31770330,
chr21-31772220-31773460,
chr21-31774067-31774624,
chr21-31776710-31776859,
chr21-31778677-31779057,
chr21-31780386-31782267,
chr21-31783965-31788184,
chr21-31788928-31789494,
chr21-31795940-31796354,
chr21-31799656-31801067,
chr21-31843522-31843806,
chr21-31845092-31845578,
chr21-31846765-31846994,
chr21-31847336-31847670,
chr21-31851015-31851259,
chr21-31851947-31852172,
chr21-31855210-31855593,
chr21-31857356-31857673,
chr21-31862100-31862414,
chr21-31863205-31863716,
chr21-31864316-31868880,
chr21-31869101-31869249,
chr21-31870626-31876394,
chr21-31879191-31880604,
chr21-31880837-31881297,
chr21-31885133-31885977,
chr21-31886766-31887046,
chr21-31887520-31887771,
chr21-31888931-31889583,
chr21-31890447-31891698,
chr21-31892180-31893001,
chr21-31893897-31894160,
chr21-31894562-31896089,
chr21-31896945-31897865,
chr21-31899034-31899545,
chr21-31949860-31950518,
chr21-31954932-31955194,
chr21-31968074-31968890,
chr21-31970770-31971371,
chr21-31973554-31973655,
chr21-31974576-31974810,
chr21-31977738-31978118,
chr21-31979137-31979420,
chr21-31980189-31981046,
chr21-31983009-31983792,
chr21-31985307-31986138,
chr21-31986414-31988047,
chr21-31988683-31989200,
chr21-31990202-31990791,
chr21-31991513-31992746,
chr21-31993758-31994696,
chr21-31996734-31997182,
chr21-31998160-31999689,
chr21-32001051-32001696,
chr21-32006901-32008003,
chr21-32017943-32018658,
chr21-32019740-32022472,
chr21-32024241-32024630,
chr21-32049756-32050545,
chr21-32054761-32055126,
chr21-32056844-32057061,
chr21-32063486-32063554,
chr21-32065461-32066038,
chr21-32067081-32068048,
chr21-32070620-32071627,
chr21-32073717-32074345,
chr21-32075068-32075437,
chr21-32076251-32077638,
chr21-32080346-32080864,
chr21-32082220-32082966,
chr21-32083237-32083710,
chr21-32084044-32084525,
chr21-32088574-32088818,
chr21-32092232-32092466,
chr21-32093737-32094360,
chr21-32095485-32097938,
chr21-32098632-32099431,
chr21-32099703-32101172,
chr21-32102092-32102845,
chr21-32110978-32111241,
chr21-32114504-32114905,
chr21-32115776-32115883,
chr21-32122159-32122402,
chr21-32125160-32125523,
chr21-32130093-32130325,
chr21-32131131-32131601,
chr21-32132045-32132447,
chr21-32133382-32134068,
chr21-32134466-32136596,
chr21-32137895-32138483,
chr21-32140072-32141469,
chr21-32143117-32144304,
chr21-32263244-32263640,
chr21-32264631-32265932,
chr21-32266164-32267358,
chr21-32276135-32276434,
chr21-32277427-32280137,
chr21-32283338-32283575,
chr21-32283821-32284221,
chr21-32551895-32552608,
chr21-32555986-32556336,
chr21-32559531-32560122,
chr21-32560770-32563200,
chr21-32563471-32563819,
chr21-32565876-32566407,
chr21-32566765-32568083,
chr21-32569005-32571301,
chr21-32571677-32572067,
chr21-32572278-32573787,
chr21-32574949-32576472,
chr21-32576694-32579657,
chr21-32580005-32580573,
chr21-32580904-32582331,
chr21-32583026-32584806,
chr21-32585090-32585613,
chr21-32586300-32587559,
chr21-32590405-32590668,
chr21-32590870-32591197,
chr21-32592176-32593983,
chr21-32594251-32594977,
chr21-32595506-32596052,
chr21-32596424-32597923,
chr21-32598775-32602954,
chr21-32603193-32603581,
chr21-32604431-32605130,
chr21-32610128-32610562,
chr21-32610963-32613801,
chr21-32614942-32615265,
chr21-32618034-32618378,
chr21-32618831-32619540,
chr21-32620088-32620453,
chr21-32621102-32621530,
chr21-32624498-32625154,
-
Co-expression with cohesin genes Rho = 0.5815
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.348
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.893
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MCF-10A,MB157,Keratinocytes192627,H1-Mesenchymal,H1-Mesendoderm,Olfactory,MCF-7,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,H1-Trophectoderm,H9-hESC,iPSC,REC-1,ARPE-19,HCT-116,OCI-AML-3,Hep-G2,Kelly,H1-hESC,HCC1599,Motor-Neuron,MSLCL,U-937,HUES64,CyT49-hESC,HUVEC,RT-112,CyT49-endoderm,CyT49-Gut,CC-2551,HAP1,HFF-hTERT
- Related loop:
chr21:29425000-29450000~~chr21:32275000-32300000,
chr21:31100000-31125000~~chr21:32250000-32275000,
chr21:31125000-31150000~~chr21:32275000-32300000,
chr21:31150000-31175000~~chr21:32250000-32275000,
chr21:31175000-31200000~~chr21:32250000-32275000,
chr21:31200000-31225000~~chr21:32250000-32275000,
chr21:31725000-31750000~~chr21:32250000-32275000,
chr21:31750000-31775000~~chr21:32250000-32275000,
chr21:31775000-31800000~~chr21:32250000-32275000,
chr21:31785218-31787331~~chr21:32277768-32279016,
chr21:31825000-31850000~~chr21:32250000-32275000,
chr21:31850000-31875000~~chr21:32250000-32275000,
chr21:31850000-31875000~~chr21:32275000-32300000,
chr21:31875000-31900000~~chr21:32250000-32275000,
chr21:31950000-31975000~~chr21:32250000-32275000,
chr21:31975000-32000000~~chr21:32250000-32275000,
chr21:32000000-32025000~~chr21:32250000-32275000,
chr21:32050000-32075000~~chr21:32250000-32275000,
chr21:32075000-32100000~~chr21:32250000-32275000,
chr21:32100000-32125000~~chr21:32250000-32275000,
chr21:32125000-32150000~~chr21:32250000-32275000,
chr21:32250000-32275000~~chr21:32550000-32575000,
chr21:32275000-32300000~~chr21:32550000-32575000,
chr21:32275000-32300000~~chr21:32575000-32600000,
chr21:32275000-32300000~~chr21:32600000-32625000,
chr21:32277555-32280325~~chr21:32599877-32601833,
chr21:32277665-32280330~~chr21:32599933-32601810,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE95015, GSE43070, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, 4DNFIDSWKFF5, 4DNFIZ4F74QR, 4DNFI7H4II2V, ENCSR350NJV, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, 4DNFI6XD6JAQ, 4DNFIK61ILGM, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, 4DNFI7XAZNNQ, GSE105028, 4DNFIBKZK63V, 4DNFIQWD8ZYD, ENCSR662QKG, GSE94872, ENCSR499RVD, 4DNFIB7QTIMH, GSE126792, 4DNFIOX3BGNE, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, Direct, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, 4DNFI9815EEJ, 4DNFI9ZWZ5BS, 4DNFIVJ3IIQL, 4DNFI2J1ODWB, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIR8OU6QJ, 4DNFI6CWNUFL, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, 4DNFIPV5KFMK, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, 4DNFIL9M97T2, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIJ7OAIFQ, 4DNFIM2BMJ33, GSE165038, 4DNFIALNLR78, 4DNFIYDBBSE3, ENCSR379CII, 4DNFIEJEFCAM, ENCSR393LOP, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR094EIC, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, ENCSR866FWQ, 4DNFI6EIFUZI, 4DNFII6AN691, GSE111537, 4DNFIV239W4L, 4DNFIOUSETUP, 4DNFISTWNV9C, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFI8JFOAJT, 4DNFIOCW5AEM, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR110JOO, 4DNFI5LCW273, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: SLK,OCI-AML-3,P3HR-1,K-562,MCF-10A,U2OS,Keratinocytes
- Cohesin-DEGs, number of studies: 13
- Cohesin-DEGs, study: GSE83870,GSE140651,GSE111537,GSE101921,GSE154086,GSE131448,GSE138937,GSE89799
- Cohesin-DEGs, subunit: SMC3,SA2,CTCF,SMC1,Rad21