Deatailed information for gene ENSG00000159082
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010288
- Gene Symbol: SYNJ1
- Ensembl ID: ENSG00000159082
-
Gene locus: chr21:32628758-32728040
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-31679593-31679852,
chr21-31681359-31681588,
chr21-31682687-31683516,
chr21-31685889-31686857,
chr21-31687804-31688047,
chr21-31690175-31690448,
chr21-31695434-31696225,
chr21-31705596-31706060,
chr21-31706429-31706648,
chr21-31707652-31707856,
chr21-31708059-31708349,
chr21-31710228-31711264,
chr21-31711898-31712847,
chr21-31713383-31713742,
chr21-31714124-31714482,
chr21-31716096-31716505,
chr21-31717839-31718283,
chr21-31719496-31719724,
chr21-31720387-31721045,
chr21-31722659-31722899,
chr21-31725854-31726651,
chr21-31727461-31727835,
chr21-31728911-31729266,
chr21-31729532-31733952,
chr21-31734532-31735896,
chr21-31737021-31738863,
chr21-31739215-31739559,
chr21-31744136-31744783,
chr21-31745048-31745345,
chr21-31749551-31751240,
chr21-31851015-31851259,
chr21-31851947-31852172,
chr21-31855210-31855593,
chr21-31857356-31857673,
chr21-31862100-31862414,
chr21-31863205-31863716,
chr21-31864316-31868880,
chr21-31869101-31869249,
chr21-31870626-31876394,
chr21-31977738-31978118,
chr21-31979137-31979420,
chr21-31980189-31981046,
chr21-31983009-31983792,
chr21-31985307-31986138,
chr21-31986414-31988047,
chr21-31988683-31989200,
chr21-31990202-31990791,
chr21-31991513-31992746,
chr21-31993758-31994696,
chr21-31996734-31997182,
chr21-31998160-31999689,
chr21-32075068-32075437,
chr21-32076251-32077638,
chr21-32080346-32080864,
chr21-32082220-32082966,
chr21-32083237-32083710,
chr21-32084044-32084525,
chr21-32088574-32088818,
chr21-32092232-32092466,
chr21-32093737-32094360,
chr21-32095485-32097938,
chr21-32098632-32099431,
chr21-32099703-32101172,
chr21-32276135-32276434,
chr21-32277427-32280137,
chr21-32283338-32283575,
chr21-32283821-32284221,
chr21-32284918-32285277,
chr21-32287224-32287305,
chr21-32294066-32294397,
chr21-32295053-32296161,
chr21-32298101-32299158,
chr21-32299751-32300868,
chr21-32301692-32301838,
chr21-32304893-32304989,
chr21-32305776-32306803,
chr21-32307314-32307797,
chr21-32308617-32310741,
chr21-32311435-32312117,
chr21-32312390-32312669,
chr21-32313137-32313329,
chr21-32314800-32315445,
chr21-32315753-32317229,
chr21-32317515-32318325,
chr21-32319081-32319441,
chr21-32319827-32320459,
chr21-32320782-32321118,
chr21-32321609-32323171,
chr21-32323561-32324126,
chr21-32324577-32324835,
chr21-32348772-32352012,
chr21-32352521-32353449,
chr21-32353738-32354082,
chr21-32355525-32355982,
chr21-32357912-32358164,
chr21-32358689-32359007,
chr21-32359599-32360314,
chr21-32361562-32361824,
chr21-32362356-32363268,
chr21-32364267-32365213,
chr21-32365681-32366109,
chr21-32368660-32369139,
chr21-32371758-32373234,
chr21-32374258-32374575,
chr21-32377005-32377825,
chr21-32379033-32379799,
chr21-32381416-32385002,
chr21-32385478-32386069,
chr21-32386291-32386639,
chr21-32386870-32387447,
chr21-32388340-32390195,
chr21-32392163-32394318,
chr21-32394704-32394805,
chr21-32397459-32397677,
chr21-32401093-32405487,
chr21-32405735-32406834,
chr21-32408217-32408697,
chr21-32409703-32410211,
chr21-32410923-32416711,
chr21-32417894-32418785,
chr21-32420222-32420681,
chr21-32422799-32425391,
chr21-32498609-32500453,
chr21-32501923-32502381,
chr21-32502858-32503479,
chr21-32506555-32507085,
chr21-32507382-32508856,
chr21-32509210-32510394,
chr21-32511129-32511347,
chr21-32514665-32515061,
chr21-32515682-32517377,
chr21-32517976-32518345,
chr21-32519053-32526591,
chr21-32598775-32602954,
chr21-32603193-32603581,
chr21-32604431-32605130,
chr21-32610128-32610562,
chr21-32610963-32613801,
chr21-32614942-32615265,
chr21-32618034-32618378,
chr21-32618831-32619540,
chr21-32620088-32620453,
chr21-32621102-32621530,
chr21-32624498-32625154,
chr21-32626571-32626979,
chr21-32627737-32628194,
chr21-32638158-32638752,
chr21-32640287-32640624,
chr21-32641807-32642758,
chr21-32645207-32646681,
chr21-32649686-32650031,
chr21-32652266-32654844,
chr21-32656100-32656468,
chr21-32658231-32658886,
chr21-32659615-32660147,
chr21-32660445-32661444,
chr21-32661750-32662259,
chr21-32668006-32668064,
chr21-32679338-32679541,
chr21-32682583-32683488,
chr21-32684885-32685224,
chr21-32687754-32688589,
chr21-32689285-32689714,
chr21-32692284-32692883,
chr21-32693837-32694604,
chr21-32695762-32696188,
chr21-32699032-32699397,
chr21-32701356-32701691,
chr21-32702794-32703230,
chr21-32709291-32709521,
chr21-32710895-32711202,
chr21-32711670-32712519,
chr21-32717971-32718233,
chr21-32719376-32719676,
chr21-32721403-32721642,
chr21-32726512-32729587,
chr21-32732552-32732879,
chr21-32753932-32754480,
chr21-32757827-32758170,
chr21-32760835-32760984,
chr21-32769734-32773333,
chr21-32802706-32803538,
chr21-32803790-32803983,
chr21-32807381-32809281,
chr21-32810267-32810567,
chr21-32813428-32813843,
chr21-32818375-32819306,
chr21-32819649-32820186,
chr21-32821902-32822259,
chr21-32822753-32823042,
chr21-32824831-32828372,
chr21-32830402-32830634,
chr21-32831636-32833765,
chr21-32834854-32835342,
chr21-32836285-32836542,
chr21-32844499-32845578,
chr21-32846527-32846785,
chr21-32853451-32853797,
chr21-32856932-32857599,
chr21-32858640-32859762,
chr21-32861838-32862114,
chr21-32863954-32864317,
chr21-32865099-32865345,
chr21-32866286-32866550,
chr21-32867727-32867938,
chr21-32868648-32869243,
chr21-32870502-32871650,
chr21-32874927-32875485,
chr21-32878661-32879234,
chr21-32884034-32884908,
chr21-32886279-32887460,
chr21-32887661-32888194,
chr21-32888987-32890040,
chr21-32890730-32891032,
chr21-32891359-32892052,
chr21-32892719-32893072,
chr21-32926434-32926668,
chr21-32929569-32931312,
chr21-32931964-32933359,
chr21-32934017-32934551,
chr21-32938921-32942303,
chr21-32943893-32944726,
chr21-32948912-32949468,
chr21-32951208-32951430,
chr21-32955846-32956667,
chr21-32958326-32958988,
chr21-32961985-32962736,
chr21-32965025-32966085,
chr21-32968711-32969012,
chr21-32970880-32971243,
chr21-32973939-32974357,
chr21-33122996-33130291,
chr21-33130703-33133452,
chr21-33134061-33134407,
chr21-33135833-33137308,
chr21-33137817-33138207,
chr21-33139059-33140508,
chr21-33144459-33144719,
chr21-33149149-33149999,
chr21-33152273-33153023,
chr21-33153578-33153936,
chr21-33155145-33155223,
chr21-33155469-33155911,
chr21-33157388-33157662,
chr21-33161530-33162077,
chr21-33162493-33162969,
chr21-33168880-33169528,
chr21-33171217-33171918,
chr21-33173420-33173661,
chr21-33176533-33177231,
chr21-33178927-33179239,
chr21-33180031-33180867,
chr21-33181665-33182455,
chr21-33183559-33184328,
chr21-33185051-33185236,
chr21-33185475-33185847,
chr21-33186452-33186919,
chr21-33189336-33190586,
chr21-33191132-33191643,
chr21-33192567-33193025,
chr21-33193411-33193657,
chr21-33194152-33195061,
chr21-33195338-33206151,
chr21-33346315-33351403,
chr21-33354048-33354418,
chr21-33355143-33356443,
chr21-33356778-33357973,
chr21-33359012-33364862,
chr21-33365781-33366490,
chr21-33367651-33369218,
chr21-33369612-33369909,
chr21-33370154-33370407,
chr21-33371268-33371854,
chr21-33372144-33385560,
chr21-33385830-33386823,
chr21-33387293-33390415,
chr21-33390737-33395496,
chr21-33395831-33399196,
chr21-33399401-33399800,
chr21-33400356-33408549,
chr21-33408842-33409547,
chr21-33409784-33417376,
chr21-33417627-33420477,
chr21-33420917-33421930,
chr21-33422693-33423726,
chr21-33423966-33426664,
chr21-33427110-33427633,
chr21-33428595-33430128,
chr21-33430846-33431848,
chr21-33432435-33436842,
chr21-33437463-33438154,
chr21-33438470-33439663,
chr21-33440299-33447453,
chr21-33448010-33448871,
chr21-33449679-33449894,
chr21-33450273-33450522,
chr21-33451723-33452456,
chr21-33456202-33456396,
chr21-33463002-33463264,
chr21-33464168-33464731,
chr21-33465490-33466234,
chr21-33467295-33467688,
chr21-33470245-33470858,
chr21-33471801-33472724,
chr21-33474539-33475875,
chr21-33525904-33526454,
chr21-33527092-33527653,
chr21-33529525-33530162,
chr21-33532796-33533465,
chr21-33533755-33533994,
chr21-33534392-33534803,
chr21-33535665-33535965,
chr21-33538818-33539084,
chr21-33539455-33539677,
chr21-33540381-33546238,
chr21-33546540-33546789,
chr21-33547026-33547321,
chr21-33547807-33548397,
chr21-33548736-33549040,
chr21-33549851-33553567,
chr21-33555465-33555687,
chr21-33557350-33557775,
chr21-33559351-33559571,
chr21-33559859-33560148,
chr21-33562137-33563192,
chr21-33564641-33564857,
chr21-33569523-33570179,
chr21-33572330-33572767,
-
Co-expression with cohesin genes Rho = 0.5614
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.348
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.902
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,Keratinocytes192627,GM12892,hTERT-HME1,H1-Mesenchymal,Olfactory,Hepatocyte-H9,GM19239,MCF-7,GM12891,GM12878,K-562,A-549,HFFc6,PAEC,HeLa-S3,SU-DHL-2,H9-hESC,KU-19-19,NCI-H1437,Liver,REC-1,Hep-G2,HT-1197,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,NaiveB,HUES64,SU-DHL-4,HUVEC,NPC-H9,RT-112,KBM-7,Jurkat,CC-2551,HFF-hTERT,HAP1,MCF7-FASR,U251
- Related loop:
chr21:25725000-25750000~~chr21:32600000-32625000,
chr21:29050000-29075000~~chr21:32625000-32650000,
chr21:29050000-29075000~~chr21:32725000-32750000,
chr21:31675000-31700000~~chr21:32725000-32750000,
chr21:31700000-31725000~~chr21:32600000-32625000,
chr21:31725000-31750000~~chr21:32600000-32625000,
chr21:31850000-31875000~~chr21:32600000-32625000,
chr21:31975000-32000000~~chr21:32600000-32625000,
chr21:32075000-32100000~~chr21:32600000-32625000,
chr21:32275000-32300000~~chr21:32600000-32625000,
chr21:32300000-32325000~~chr21:32600000-32625000,
chr21:32300000-32325000~~chr21:32725000-32750000,
chr21:32350000-32375000~~chr21:32600000-32625000,
chr21:32350000-32375000~~chr21:32725000-32750000,
chr21:32375000-32400000~~chr21:32600000-32625000,
chr21:32375000-32400000~~chr21:32700000-32725000,
chr21:32375000-32400000~~chr21:32725000-32750000,
chr21:32400000-32425000~~chr21:32600000-32625000,
chr21:32400000-32425000~~chr21:32725000-32750000,
chr21:32500000-32525000~~chr21:32600000-32625000,
chr21:32600000-32625000~~chr21:32725000-32750000,
chr21:32625000-32650000~~chr21:32725000-32750000,
chr21:32625000-32650000~~chr21:32800000-32825000,
chr21:32625000-32650000~~chr21:32850000-32875000,
chr21:32625000-32650000~~chr21:33125000-33150000,
chr21:32650000-32675000~~chr21:32750000-32775000,
chr21:32650000-32675000~~chr21:32800000-32825000,
chr21:32650000-32675000~~chr21:32825000-32850000,
chr21:32650000-32675000~~chr21:32875000-32900000,
chr21:32650000-32675000~~chr21:32925000-32950000,
chr21:32650000-32675000~~chr21:32950000-32975000,
chr21:32650000-32675000~~chr21:33125000-33150000,
chr21:32650000-32675000~~chr21:33175000-33200000,
chr21:32650000-32675000~~chr21:33425000-33450000,
chr21:32650000-32675000~~chr21:33450000-33475000,
chr21:32652383-32654378~~chr21:32825782-32827815,
chr21:32652386-32654426~~chr21:32726210-32729172,
chr21:32652386-32654426~~chr21:32825831-32827860,
chr21:32652386-32654426~~chr21:33196166-33197911,
chr21:32652389-32654469~~chr21:32825808-32827779,
chr21:32652409-32654456~~chr21:32825866-32827872,
chr21:32652429-32654433~~chr21:32825838-32827744,
chr21:32652434-32654776~~chr21:32825826-32827775,
chr21:32652483-32654348~~chr21:32825846-32827753,
chr21:32652489-32654409~~chr21:32825799-32827554,
chr21:32652499-32654463~~chr21:32825893-32827718,
chr21:32652499-32654463~~chr21:33196237-33197895,
chr21:32652522-32654350~~chr21:32825860-32827784,
chr21:32652542-32654360~~chr21:32825800-32827808,
chr21:32652542-32654360~~chr21:33196187-33197905,
chr21:32652578-32654325~~chr21:32825867-32827535,
chr21:32652587-32654469~~chr21:32825810-32827769,
chr21:32652605-32654451~~chr21:32825841-32827928,
chr21:32652616-32654320~~chr21:32825846-32827910,
chr21:32652635-32654427~~chr21:32825998-32827550,
chr21:32652673-32654332~~chr21:32825859-32827579,
chr21:32652681-32654365~~chr21:32825879-32827591,
chr21:32652689-32654365~~chr21:32825802-32827847,
chr21:32652693-32654360~~chr21:32825812-32827756,
chr21:32652694-32654377~~chr21:32825818-32827923,
chr21:32652697-32654249~~chr21:32825837-32827613,
chr21:32652727-32654348~~chr21:32825866-32827565,
chr21:32652742-32654378~~chr21:32825904-32827533,
chr21:32652754-32654437~~chr21:32825782-32827847,
chr21:32652755-32654212~~chr21:32826064-32827444,
chr21:32652755-32654315~~chr21:32727492-32729158,
chr21:32652769-32654256~~chr21:32826020-32827524,
chr21:32652778-32654242~~chr21:32826025-32827540,
chr21:32652779-32654447~~chr21:33360228-33362109,
chr21:32652835-32654360~~chr21:32825859-32827506,
chr21:32652869-32654298~~chr21:32825892-32827470,
chr21:32652869-32654298~~chr21:33444420-33446284,
chr21:32660370-32661816~~chr21:32825818-32827923,
chr21:32675000-32700000~~chr21:32825000-32850000,
chr21:32675000-32700000~~chr21:32925000-32950000,
chr21:32675000-32700000~~chr21:32950000-32975000,
chr21:32675000-32700000~~chr21:33150000-33175000,
chr21:32675000-32700000~~chr21:33175000-33200000,
chr21:32675000-32700000~~chr21:33400000-33425000,
chr21:32686727-32688995~~chr21:32825782-32827815,
chr21:32686771-32689009~~chr21:32825818-32827923,
chr21:32687246-32688984~~chr21:32726251-32729172,
chr21:32687246-32688984~~chr21:32825812-32827756,
chr21:32687269-32688980~~chr21:32825841-32827928,
chr21:32687309-32688956~~chr21:32825826-32827775,
chr21:32687321-32688946~~chr21:32825808-32827779,
chr21:32687460-32688668~~chr21:32726790-32728912,
chr21:32687493-32688873~~chr21:32770782-32773207,
chr21:32687503-32689164~~chr21:32825859-32827579,
chr21:32687504-32688956~~chr21:32825998-32827550,
chr21:32687515-32688913~~chr21:32825840-32827525,
chr21:32700000-32725000~~chr21:32800000-32825000,
chr21:32700000-32725000~~chr21:32850000-32875000,
chr21:32700000-32725000~~chr21:32875000-32900000,
chr21:32725000-32750000~~chr21:32850000-32875000,
chr21:32725000-32750000~~chr21:33350000-33375000,
chr21:32725000-32750000~~chr21:33375000-33400000,
chr21:32725000-32750000~~chr21:33525000-33550000,
chr21:32725000-32750000~~chr21:33550000-33575000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
GSE95015, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, 4DNFIBN9K4V9, ENCSR852KQC, ENCSR361AYD, 4DNFI7H4II2V, 4DNFIREVU1Z5, 4DNFI9VXTBE2, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR000FDB, ENCSR527RXH, GSE105028, ENCSR833CMG, ENCSR033GUP, 4DNFI3CFMRID, ENCSR662QKG, GSE118716, ENCSR499RVD, ENCSR146FPM, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, Direct, ENCSR479MTN, 4DNFIH9U4I7I, 4DNFIX7H3CE2, ENCSR244BBG, ENCSR991JXX, 4DNFI9ZWZ5BS, 4DNFIVJ3IIQL, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIT96Z365, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, 4DNFIBM714BP, 4DNFIYD8LO9Z, 4DNFIL9M97T2, 4DNFI3A3VYWU, 4DNFIM2BMJ33, 4DNFIBY3UHJB, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE125243, 4DNFIPAF4PYT, ENCSR404HWQ, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, GSE58752, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFII6AN691, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, ENCSR752QCX, ENCSR128RPG, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, 4DNFI8JFOAJT, 4DNFIOCW5AEM, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR338WUS, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: HPC,SLK,MCF-10A,HAP1,HeLa-S3
- Cohesin-DEGs, number of studies: 7
- Cohesin-DEGs, study: GSE139845,GSE101921,GSE119828,GSE126635,GSE138937,GSE108869,GSE130558
- Cohesin-DEGs, subunit: WAPL,SA1,CdLS,CTCF