Deatailed information for gene ENSG00000159131
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010293
- Gene Symbol: GART
- Ensembl ID: ENSG00000159131
-
Gene locus: chr21:33524008-33542114
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-32328118-32330129,
chr21-32330737-32331391,
chr21-32331697-32332156,
chr21-32334113-32336149,
chr21-32336796-32337602,
chr21-32338550-32338885,
chr21-32339467-32340569,
chr21-32341274-32341813,
chr21-32345342-32345734,
chr21-32346632-32348222,
chr21-32348772-32352012,
chr21-32352521-32353449,
chr21-32353738-32354082,
chr21-32355525-32355982,
chr21-32357912-32358164,
chr21-32358689-32359007,
chr21-32359599-32360314,
chr21-32361562-32361824,
chr21-32362356-32363268,
chr21-32364267-32365213,
chr21-32365681-32366109,
chr21-32368660-32369139,
chr21-32371758-32373234,
chr21-32374258-32374575,
chr21-32377005-32377825,
chr21-32379033-32379799,
chr21-32381416-32385002,
chr21-32385478-32386069,
chr21-32386291-32386639,
chr21-32386870-32387447,
chr21-32388340-32390195,
chr21-32392163-32394318,
chr21-32394704-32394805,
chr21-32397459-32397677,
chr21-32726512-32729587,
chr21-32732552-32732879,
chr21-32753932-32754480,
chr21-32757827-32758170,
chr21-32760835-32760984,
chr21-32769734-32773333,
chr21-33372144-33385560,
chr21-33385830-33386823,
chr21-33387293-33390415,
chr21-33390737-33395496,
chr21-33395831-33399196,
chr21-33399401-33399800,
chr21-33519154-33519618,
chr21-33521344-33521870,
chr21-33523382-33523959,
chr21-33525904-33526454,
chr21-33527092-33527653,
chr21-33529525-33530162,
chr21-33532796-33533465,
chr21-33533755-33533994,
chr21-33534392-33534803,
chr21-33535665-33535965,
chr21-33538818-33539084,
chr21-33539455-33539677,
chr21-33540381-33546238,
chr21-33546540-33546789,
chr21-33547026-33547321,
chr21-33600574-33601299,
chr21-33603909-33604583,
chr21-33605200-33607038,
chr21-33607346-33608402,
chr21-33608659-33608932,
chr21-33609731-33610466,
chr21-33610749-33611018,
chr21-33612271-33612631,
chr21-33616311-33616612,
chr21-33617012-33618282,
chr21-33620585-33621673,
chr21-33622979-33623244,
chr21-33624861-33625767,
chr21-33675259-33675593,
chr21-33678520-33679233,
chr21-33681669-33681950,
chr21-33682198-33684451,
chr21-33684696-33686775,
chr21-33687051-33688043,
chr21-33688329-33690064,
chr21-33690301-33691242,
chr21-33692275-33692558,
chr21-33693364-33693628,
chr21-33695730-33696319,
chr21-33892684-33896819,
chr21-34050402-34050635,
chr21-34050980-34051129,
chr21-34052018-34052178,
chr21-34052673-34053743,
chr21-34055195-34056225,
chr21-34056635-34056904,
chr21-34057409-34058775,
chr21-34058985-34059676,
chr21-34061874-34062292,
chr21-34065023-34065565,
chr21-34066661-34066866,
chr21-34067086-34067512,
chr21-34070416-34071494,
chr21-34071705-34071912,
chr21-34072131-34076800,
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Co-expression with cohesin genes Rho = 0.6425
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.284
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.898
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: HL-60,iPSC,Liver,GM12878,H1-hESC,A-549,HAP1,HFFc6,PAEC,H9-hESC,CyT49-hESC
- Related loop:
chr21:29025000-29050000~~chr21:33525000-33550000,
chr21:29050000-29075000~~chr21:33500000-33525000,
chr21:32325000-32350000~~chr21:33500000-33525000,
chr21:32325000-32350000~~chr21:33525000-33550000,
chr21:32350000-32375000~~chr21:33525000-33550000,
chr21:32375000-32400000~~chr21:33500000-33525000,
chr21:32725000-32750000~~chr21:33525000-33550000,
chr21:32750000-32775000~~chr21:33525000-33550000,
chr21:33375000-33400000~~chr21:33500000-33525000,
chr21:33375000-33400000~~chr21:33525000-33550000,
chr21:33500000-33525000~~chr21:33600000-33625000,
chr21:33500000-33525000~~chr21:37150000-37175000,
chr21:33525000-33550000~~chr21:33675000-33700000,
chr21:33525000-33550000~~chr21:34050000-34075000,
chr21:33541043-33543518~~chr21:33893790-33895862,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
ENCSR662QKG, GSE95015, 4DNFIMROE6N4, ENCSR499RVD, 4DNFI5SUHCGZ, ENCSR410MDC, 4DNFII6AN691, 4DNFIKYXMF1E, 4DNFIYD8LO9Z, ENCSR668RDP, GSE131580, 4DNFIIMZB6Y9, Direct, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, ENCSR244BBG, ENCSR393LOP, GSE105028, GSE58752, 4DNFII84FBKM, 4DNFIVSCH2CH
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: SLK,P3HR-1,K-562,U2OS,Keratinocytes,Kasumi-1
- Cohesin-DEGs, number of studies: 8
- Cohesin-DEGs, study: GSE83870,GSE140651,GSE138937,GSE131448,GSE89799,GSE47641
- Cohesin-DEGs, subunit: SMC3,SA2,CTCF,Rad21,SMC1