Deatailed information for gene ENSG00000159147
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010295
- Gene Symbol: DONSON
- Ensembl ID: ENSG00000159147
-
Gene locus: chr21:33559541-33578363
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-32726512-32729587,
chr21-32732552-32732879,
chr21-32753932-32754480,
chr21-32757827-32758170,
chr21-32760835-32760984,
chr21-32769734-32773333,
chr21-33195338-33206151,
chr21-33206645-33209519,
chr21-33209798-33210131,
chr21-33211272-33213452,
chr21-33215011-33217335,
chr21-33219732-33220309,
chr21-33222873-33223242,
chr21-33224686-33226597,
chr21-33372144-33385560,
chr21-33385830-33386823,
chr21-33387293-33390415,
chr21-33390737-33395496,
chr21-33395831-33399196,
chr21-33399401-33399800,
chr21-33555465-33555687,
chr21-33557350-33557775,
chr21-33559351-33559571,
chr21-33559859-33560148,
chr21-33562137-33563192,
chr21-33564641-33564857,
chr21-33569523-33570179,
chr21-33572330-33572767,
chr21-33575130-33575357,
chr21-33576200-33577811,
chr21-33578038-33578662,
chr21-33578902-33581040,
chr21-33582725-33583211,
chr21-33675259-33675593,
chr21-33678520-33679233,
chr21-33681669-33681950,
chr21-33682198-33684451,
chr21-33684696-33686775,
chr21-33687051-33688043,
chr21-33688329-33690064,
chr21-33690301-33691242,
chr21-33692275-33692558,
chr21-33693364-33693628,
chr21-33695730-33696319,
chr21-33700016-33700294,
chr21-33700936-33701037,
chr21-33701558-33702121,
chr21-33703645-33704316,
chr21-33704920-33705073,
chr21-33705365-33705686,
chr21-33706730-33707558,
chr21-33708388-33709548,
chr21-33711416-33711912,
chr21-33712966-33713558,
chr21-33713815-33714138,
chr21-33715952-33716503,
chr21-33717558-33717807,
chr21-33719132-33719441,
chr21-33723328-33723674,
chr21-33798590-33800042,
chr21-33800835-33802884,
chr21-33805680-33806254,
chr21-33807872-33808601,
chr21-33809823-33810159,
chr21-33811054-33812794,
chr21-33813937-33814344,
chr21-33814726-33816192,
chr21-33816580-33816843,
chr21-33817206-33818547,
chr21-33819690-33821242,
chr21-33821453-33822435,
chr21-33824293-33824912,
chr21-33873576-33876182,
chr21-33877070-33877376,
chr21-33877772-33878324,
chr21-33878528-33879672,
chr21-33879940-33881651,
chr21-33882293-33882835,
chr21-33883363-33885590,
chr21-33885973-33886683,
chr21-33887788-33889149,
chr21-33890890-33891210,
chr21-33892684-33896819,
chr21-33898105-33899425,
chr21-33899805-33900206,
chr21-33901298-33903251,
chr21-33904131-33904969,
chr21-33913803-33916898,
chr21-33917462-33917726,
chr21-33918896-33919235,
chr21-33921048-33926629,
chr21-34199128-34205356,
chr21-34205572-34206804,
chr21-34207665-34207765,
chr21-34217743-34218130,
chr21-34219966-34220375,
chr21-34221388-34222210,
chr21-34222518-34224255,
chr21-34344734-34353465,
chr21-34355390-34355626,
chr21-34356201-34356732,
chr21-34360486-34364137,
chr21-34364518-34364800,
chr21-34365500-34365847,
chr21-34366487-34368638,
chr21-34369248-34369608,
chr21-34371955-34372730,
chr21-34373717-34374267,
chr21-34374742-34376256,
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Co-expression with cohesin genes Rho = 0.6374
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.326
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.863
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: HEK293T,K-562,MCF-10A,TAMR-MCF7,H1-hESC,A-549,HFF-hTERT,HAP1,HFFc6,HeLa-S3,H1-Trophectoderm,H9-hESC,Olfactory,HUES64
- Related loop:
chr21:29050000-29075000~~chr21:33550000-33575000,
chr21:32725000-32750000~~chr21:33550000-33575000,
chr21:32750000-32775000~~chr21:33550000-33575000,
chr21:33200000-33225000~~chr21:33550000-33575000,
chr21:33200000-33225000~~chr21:33575000-33600000,
chr21:33375000-33400000~~chr21:33550000-33575000,
chr21:33550000-33575000~~chr21:33700000-33725000,
chr21:33550000-33575000~~chr21:33800000-33825000,
chr21:33550000-33575000~~chr21:33900000-33925000,
chr21:33550000-33575000~~chr21:34200000-34225000,
chr21:33550000-33575000~~chr21:36350000-36375000,
chr21:33575000-33600000~~chr21:33675000-33700000,
chr21:33575000-33600000~~chr21:33700000-33725000,
chr21:33575000-33600000~~chr21:33875000-33900000,
chr21:33575000-33600000~~chr21:33900000-33925000,
chr21:33575000-33600000~~chr21:34350000-34375000,
- Cohesin-loop type: HiChIP,HiC,Direct
- Cohesin-loop study:
4DNFIQWD8ZYD, ENCSR662QKG, GSE95015, GSE118716, ENCSR499RVD, 4DNFI5SUHCGZ, 4DNFIBM714BP, 4DNFIYD8LO9Z, GSE97394, 4DNFIIMZB6Y9, 4DNFIE8T8JZ8, GSE52457, 4DNFI3A3VYWU, 4DNFIM2BMJ33, Direct, 4DNFISPUVQHA, GSE101921, ENCSR393LOP, GSE44267, GSE105028, 4DNFIDBIEXI7, 4DNFII84FBKM
- Cohesin-loop subunit: CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: U2OS,Kelly,P3HR-1
- Cohesin-DEGs, number of studies: 3
- Cohesin-DEGs, study: GSE115253,GSE140651,GSE89799
- Cohesin-DEGs, subunit: SMC1,Rad21,BORIS