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Basic information

CohesinDB ID: CDBG00010313

Gene Symbol: RUNX1

Ensembl ID: ENSG00000159216

Gene locus: chr21:34787800-35049344 Strand: -

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-33899805-33900206, chr21-33901298-33903251, chr21-33904131-33904969, chr21-33913803-33916898, chr21-33917462-33917726, chr21-33918896-33919235, chr21-33921048-33926629, chr21-33946584-33950682, chr21-33951082-33952547, chr21-33953313-33953520, chr21-33956181-33956281, chr21-33961186-33962466, chr21-33963087-33963651, chr21-33964274-33965220, chr21-33966349-33970266, chr21-33970541-33972949, chr21-33973187-33974166, chr21-33974402-33978652, chr21-34344734-34353465, chr21-34355390-34355626, chr21-34356201-34356732, chr21-34360486-34364137, chr21-34364518-34364800, chr21-34365500-34365847, chr21-34366487-34368638, chr21-34369248-34369608, chr21-34371955-34372730, chr21-34373717-34374267, chr21-34374742-34376256, chr21-34501761-34502015, chr21-34504010-34504283, chr21-34504884-34505791, chr21-34506232-34507063, chr21-34508107-34513689, chr21-34514406-34516103, chr21-34516659-34519824, chr21-34520257-34523372, chr21-34523800-34530931, chr21-34531262-34532028, chr21-34532557-34533261, chr21-34533706-34535019, chr21-34535906-34537698, chr21-34538488-34538934, chr21-34541693-34541899, chr21-34542587-34546109, chr21-34546467-34546852, chr21-34547080-34547346, chr21-34548664-34549336, chr21-34551283-34551653, chr21-34551944-34554534, chr21-34555773-34556021, chr21-34556897-34557364, chr21-34558172-34558436, chr21-34561718-34561979, chr21-34563889-34564523, chr21-34564942-34565180, chr21-34565916-34566327, chr21-34569352-34570137, chr21-34570400-34570594, chr21-34571564-34572414, chr21-34598744-34600193, chr21-34600852-34607197, chr21-34607735-34607972, chr21-34609310-34609958, chr21-34610309-34610570, chr21-34612457-34613145, chr21-34613828-34615776, chr21-34616709-34617250, chr21-34618035-34618756, chr21-34622856-34623945, chr21-34675632-34675953, chr21-34678012-34678345, chr21-34679678-34680290, chr21-34682805-34683058, chr21-34686036-34686398, chr21-34686620-34687085, chr21-34687732-34691121, chr21-34692147-34696282, chr21-34697770-34698335, chr21-34699934-34700500, chr21-34701028-34701356, chr21-34701621-34704879, chr21-34705086-34705452, chr21-34707476-34708390, chr21-34710392-34710772, chr21-34712749-34713096, chr21-34715391-34715920, chr21-34716204-34717951, chr21-34718434-34718803, chr21-34719317-34720422, chr21-34720656-34720985, chr21-34721618-34723787, chr21-34725242-34725570, chr21-34726071-34727333, chr21-34728212-34729038, chr21-34730375-34730967, chr21-34732355-34732995, chr21-34733994-34735235, chr21-34735958-34737524, chr21-34738288-34738793, chr21-34739066-34739372, chr21-34742264-34742467, chr21-34742716-34748790, chr21-34749135-34749722, chr21-34751020-34751293, chr21-34752619-34752901, chr21-34753274-34753506, chr21-34754481-34755013, chr21-34757731-34758027, chr21-34758515-34759013, chr21-34760153-34761814, chr21-34762657-34763171, chr21-34763900-34764522, chr21-34766828-34767249, chr21-34768144-34768932, chr21-34769376-34769684, chr21-34771496-34772035, chr21-34772749-34773133, chr21-34774437-34775227, chr21-34775844-34776126, chr21-34780128-34780588, chr21-34781697-34781958, chr21-34782961-34783349, chr21-34784579-34784863, chr21-34785778-34786442, chr21-34787208-34788094, chr21-34788937-34789278, chr21-34790774-34791027, chr21-34791758-34793250, chr21-34793532-34794048, chr21-34794504-34797246, chr21-34798224-34798713, chr21-34799103-34799483, chr21-34800219-34800622, chr21-34800864-34803584, chr21-34803861-34805114, chr21-34806718-34810175, chr21-34810714-34811564, chr21-34812265-34817307, chr21-34817535-34820582, chr21-34821788-34822030, chr21-34822893-34823796, chr21-34826496-34828171, chr21-34830533-34831199, chr21-34832157-34832670, chr21-34833081-34847342, chr21-34847624-34848884, chr21-34849980-34869247, chr21-34870048-34873238, chr21-34874329-34876263, chr21-34876603-34893358, chr21-34894062-34895143, chr21-34895350-34895823, chr21-34897971-34898224, chr21-34900297-34900812, chr21-34901155-34901514, chr21-34903345-34903867, chr21-34904927-34905312, chr21-34906223-34909267, chr21-34909506-34911007, chr21-34911237-34917573, chr21-34918616-34918890, chr21-34922546-34922797, chr21-34923848-34924746, chr21-34926745-34927644, chr21-34928415-34928925, chr21-34930533-34931355, chr21-34932240-34932637, chr21-34933656-34935248, chr21-34935510-34937686, chr21-34937891-34940201, chr21-34940643-34941396, chr21-34942484-34943548, chr21-34943786-34944243, chr21-34945950-34948337, chr21-34949592-34949869, chr21-34951000-34951552, chr21-34952726-34953061, chr21-34953283-34953620, chr21-34953886-34954631, chr21-34956526-34957978, chr21-34958441-34958922, chr21-34959649-34961568, chr21-34962173-34966667, chr21-34967086-34970411, chr21-34970612-34970915, chr21-34973707-34974893, chr21-34977853-34978280, chr21-34978869-34979135, chr21-34981801-34982247, chr21-34982607-34985119, chr21-34986011-34990433, chr21-34990740-34994113, chr21-34994490-34995844, chr21-34996052-35001042, chr21-35002028-35002756, chr21-35002958-35004576, chr21-35004805-35006018, chr21-35006862-35007688, chr21-35010595-35010671, chr21-35011346-35012385, chr21-35014051-35015191, chr21-35015441-35016447, chr21-35017299-35017798, chr21-35018434-35024386, chr21-35025268-35030343, chr21-35030618-35031406, chr21-35034190-35035022, chr21-35035550-35039035, chr21-35039690-35041679, chr21-35042107-35054875, chr21-35102044-35103499, chr21-35105183-35107603, chr21-35110240-35110528, chr21-35111512-35111903, chr21-35112947-35113497, chr21-35113763-35114367, chr21-35116325-35116471, chr21-35117316-35118081, chr21-35118631-35118943, chr21-35120189-35121289, chr21-35126672-35127351, chr21-35127776-35128378, chr21-35128598-35129121, chr21-35130946-35131412, chr21-35132083-35132494, chr21-35134063-35134780, chr21-35135842-35140867, chr21-35141178-35142738, chr21-35143637-35143946, chr21-35145622-35146175, chr21-35147338-35147884, chr21-35149134-35152188, chr21-35154703-35155159, chr21-35156363-35156670, chr21-35157805-35158338, chr21-35159409-35160721, chr21-35163008-35163907, chr21-35165488-35165688, chr21-35166681-35167018, chr21-35168223-35168956, chr21-35171397-35172201, chr21-35176910-35177309, chr21-35177740-35178019, chr21-35178366-35181009, chr21-35188735-35190902, chr21-35191120-35191475, chr21-35195081-35196351, chr21-35196740-35200400, chr21-35200950-35209885, chr21-35211918-35213403, chr21-35215746-35216115, chr21-35216589-35221378, chr21-35221773-35224106, chr21-35225613-35229873, chr21-35230084-35230632, chr21-35230893-35235351, chr21-35235747-35236728, chr21-35239418-35240383, chr21-35243153-35243584, chr21-35244019-35244879, chr21-35248780-35249030, chr21-35249249-35250292, chr21-35252607-35260143, chr21-35261735-35262939, chr21-35264418-35267579, chr21-35268268-35268825, chr21-35273218-35273904, chr21-35274166-35275146, chr21-35301231-35301743, chr21-35302008-35304221, chr21-35304528-35304984, chr21-35306293-35306581, chr21-35307911-35308119, chr21-35309377-35309608, chr21-35312589-35312844, chr21-35313834-35314255, chr21-35316716-35317482, chr21-35317740-35318435, chr21-35319231-35320019, chr21-35321543-35321732, chr21-35322614-35323016, chr21-35323256-35327545, chr21-35340030-35340869, chr21-35348755-35350266, chr21-35351031-35352777, chr21-35356599-35358381, chr21-35359135-35359624, chr21-35359855-35361915, chr21-35362993-35363385, chr21-35363906-35364263, chr21-35366084-35367938, chr21-35368171-35368729, chr21-35371312-35371875, chr21-35372329-35373032, chr21-35373259-35373669, chr21-35373913-35374287, chr21-35374515-35378288, chr21-35381568-35382502, chr21-35385712-35386414, chr21-35390026-35390708, chr21-35392967-35393548, chr21-35394657-35397476, chr21-35397987-35402508, chr21-35402763-35403675, chr21-35403878-35404147, chr21-35404397-35406208, chr21-35407306-35409284, chr21-35409547-35410796, chr21-35411186-35412282, chr21-35417009-35417597, chr21-35420540-35421545, chr21-35423373-35425369, chr21-35431551-35432212, chr21-35500853-35500970, chr21-35503483-35504812, chr21-35505097-35505408, chr21-35505813-35513273, chr21-35517685-35518236, chr21-35520216-35522630, chr21-35524410-35526641, chr21-35573981-35576315, chr21-35576556-35580249, chr21-35580481-35581036, chr21-35582951-35583183, chr21-35583700-35584248, chr21-35585360-35587069, chr21-35589326-35589724, chr21-35592466-35593947, chr21-35597811-35598021, chr21-35598644-35598993, chr21-35600876-35601492, chr21-35602765-35603978, chr21-35604344-35604583, chr21-35604798-35605091, chr21-35606136-35607050, chr21-35608993-35609625, chr21-35611744-35612170, chr21-35613404-35617826, chr21-35618320-35620072, chr21-35622116-35622255, chr21-35622783-35623071, chr21-35624757-35626689, chr21-35628178-35628897, chr21-35629217-35629728, chr21-35630432-35630582, chr21-35632706-35633020, chr21-35633468-35633807, chr21-35634449-35638495, chr21-35640341-35642547, chr21-35642894-35644306, chr21-35646507-35647140, chr21-35648338-35649581, chr21-35728941-35729188, chr21-35730108-35730692, chr21-35733278-35733627, chr21-35735743-35736310, chr21-35737764-35739257, chr21-35742086-35742347, chr21-35743586-35743845, chr21-35744757-35744884, chr21-35745193-35746628, chr21-35749745-35749963, chr21-35826438-35826754, chr21-35829136-35829658, chr21-35831642-35832191, chr21-35833310-35833627, chr21-35834021-35834863, chr21-35835452-35836190, chr21-35836412-35837584, chr21-35837818-35843127, chr21-35843830-35845505, chr21-35849614-35851658, chr21-35852978-35854102, chr21-35855138-35855885, chr21-35857491-35857818, chr21-35861535-35862042, chr21-35873964-35875028, chr21-35924668-35926278, chr21-35927378-35927659, chr21-35931956-35934271, chr21-35938558-35942713, chr21-35946138-35946776, chr21-35974854-35975595, chr21-35976923-35977297, chr21-35978480-35978702, chr21-35981014-35981329, chr21-35982812-35982917, chr21-35983170-35983412, chr21-35984558-35985494, chr21-35986556-35987129, chr21-35989141-35989875, chr21-35991211-35992040, chr21-35992735-35993291, chr21-35994336-35994851, chr21-36020789-36021262, chr21-36023653-36025675, chr21-36026141-36034881, chr21-36035088-36035988, chr21-36037645-36037936, chr21-36038529-36039078, chr21-36039809-36040296, chr21-36040874-36041598, chr21-36044044-36044355, chr21-36044664-36044983, chr21-36045207-36046298, chr21-36047110-36047488, chr21-36048486-36048822, chr21-36099272-36100281, chr21-36103438-36103780, chr21-36104103-36105761, chr21-36108296-36108584, chr21-36111138-36114564, chr21-36117276-36118182, chr21-36120265-36121169, chr21-36122832-36123472, chr21-36299999-36300920, chr21-36301823-36302767, chr21-36303173-36303417, chr21-36306746-36307626, chr21-36308895-36312325, chr21-36312827-36313084, chr21-36315963-36316373, chr21-36316605-36317491, chr21-36318095-36323464, chr21-36323820-36325021, chr21-36674474-36675018, chr21-36679412-36679745, chr21-36685090-36686439, chr21-36689351-36689685, chr21-36691769-36693953, chr21-36694356-36695251, chr21-36695763-36711052,

Co-expression with cohesin genes Rho = 0.1980 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.562
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.877
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,Right-Ventricle,Keratinocytes192627,Aorta,GM12892,K1,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,NCI-H1437,iPSC,Liver,ARPE-19,HCT-116,REC-1,Hep-G2,HT-1197,Kelly,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,NaiveB,U-937,BMEC,HUES64,SU-DHL-4,CyT49-hESC,HUVEC,HL-60,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,KBM-7,CC-2551,CyT49-Gut,HAP1,HFF-hTERT,MCF7-FASR

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: GSE95015, GSE43070, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, GSE103148, 4DNFI7H4II2V, 4DNFIZ4F74QR, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR000FDB, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, 4DNFIBKZK63V, ENCSR033GUP, GSE87112, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, ENCSR146FPM, ENCSR478BMT, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE52457, 4DNFIBT4EAKN, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIH7TH4MF, 4DNFIT96Z365, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFI6CWNUFL, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, ENCSR123UVP, 4DNFIL9M97T2, 4DNFIJBJ6QVH, 4DNFI3A3VYWU, 4DNFIM2BMJ33, GSE165038, 4DNFIYDBBSE3, ENCSR386KHY, ENCSR379CII, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, GSE48592, ENCSR255XYX, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, GSE58752, ENCSR507AHE, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, ENCSR866FWQ, 4DNFI6EIFUZI, 4DNFII6AN691, GSE131580, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, ENCSR752QCX, ENCSR128RPG, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFIOCW5AEM, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFIP71EWXC, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: SLK,OCI-AML-3,P3HR-1,K-562,U2OS,HeLa-S3,Keratinocytes

Cohesin-DEGs, number of studies: 9

Cohesin-DEGs, study: GSE83870,GSE140651,GSE111537,GSE138937,GSE131448,GSE89799,GSE130558

Cohesin-DEGs, subunit: SMC3,SA2,WAPL,SMC1,Rad21

Tools:

Assay

refGene

Ruler

RUNX1 gene locus

RUNX1 related cohesin sites

RUNX1 related cohesin loop

Deatailed information for gene ENSG00000159216

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Suggested terms

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