Deatailed information for gene ENSG00000159231
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010317
- Gene Symbol: CBR3
- Ensembl ID: ENSG00000159231
-
Gene locus: chr21:36135078-36146562
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,
- Regulatory cohesin (double-evidenced):
chr21-34344734-34353465,
chr21-34355390-34355626,
chr21-34356201-34356732,
chr21-34360486-34364137,
chr21-34364518-34364800,
chr21-34365500-34365847,
chr21-34366487-34368638,
chr21-34369248-34369608,
chr21-34371955-34372730,
chr21-34373717-34374267,
chr21-34374742-34376256,
chr21-36122832-36123472,
chr21-36129740-36130699,
chr21-36132348-36133044,
chr21-36133297-36137447,
chr21-36138179-36138394,
chr21-36139440-36143477,
chr21-36143694-36144806,
chr21-36145249-36145917,
chr21-36146214-36147498,
chr21-36148387-36148829,
chr21-36149046-36149389,
chr21-36149733-36151341,
chr21-36207279-36213059,
chr21-36225295-36225749,
chr21-36226428-36227844,
chr21-36228278-36228734,
chr21-36229199-36230147,
chr21-36230544-36231198,
chr21-36231686-36233549,
chr21-36233845-36235845,
chr21-36236082-36238447,
chr21-36238704-36240434,
chr21-36241048-36241641,
chr21-36242382-36242625,
chr21-36245119-36246670,
chr21-36246976-36247569,
chr21-36248900-36249494,
chr21-36299999-36300920,
chr21-36301823-36302767,
chr21-36303173-36303417,
chr21-36306746-36307626,
chr21-36308895-36312325,
chr21-36312827-36313084,
chr21-36315963-36316373,
chr21-36316605-36317491,
chr21-36318095-36323464,
chr21-36323820-36325021,
chr21-36325365-36326460,
chr21-36326664-36327275,
chr21-36327639-36334205,
chr21-36334931-36335565,
chr21-36335925-36336565,
chr21-36336965-36337518,
chr21-36340013-36340333,
chr21-36340657-36340869,
chr21-36341931-36343741,
chr21-36345238-36346750,
chr21-36347303-36347666,
chr21-36348825-36349132,
chr21-36349796-36350705,
chr21-36353043-36353476,
chr21-36355218-36355790,
chr21-36358622-36359002,
chr21-36360808-36361089,
chr21-36369187-36370260,
chr21-36373061-36373546,
chr21-36374124-36374381,
chr21-36374655-36374977,
chr21-36379872-36380326,
chr21-36383536-36383931,
chr21-36384976-36386612,
chr21-36387795-36388181,
chr21-36388570-36390448,
chr21-36390697-36390999,
chr21-36392384-36394412,
chr21-36396999-36397241,
chr21-36399798-36400258,
chr21-36417281-36424270,
chr21-36499698-36502459,
chr21-36502665-36508046,
chr21-36508508-36509460,
chr21-36509687-36510756,
chr21-36511314-36511916,
chr21-36512825-36514000,
chr21-36514562-36514704,
chr21-36514932-36516116,
chr21-36516886-36517136,
chr21-36518707-36520114,
chr21-36522371-36522616,
chr21-36522943-36523216,
chr21-36523577-36525374,
chr21-36575350-36575709,
chr21-36576412-36577230,
chr21-36583668-36584068,
chr21-36584895-36585487,
chr21-36585745-36586353,
chr21-36587320-36592079,
chr21-36592299-36593515,
chr21-36594289-36594685,
chr21-36597896-36598145,
chr21-36626499-36626785,
chr21-36627115-36627703,
chr21-36628239-36628880,
chr21-36629116-36633556,
chr21-36635100-36635760,
chr21-36639730-36643030,
chr21-36643874-36644319,
chr21-36645284-36645814,
chr21-36646243-36646978,
chr21-36647229-36648099,
chr21-36649972-36650268,
chr21-36674474-36675018,
chr21-36679412-36679745,
chr21-36685090-36686439,
chr21-36689351-36689685,
chr21-36691769-36693953,
chr21-36694356-36695251,
chr21-36695763-36711052,
chr21-36900452-36900638,
chr21-36902278-36903030,
chr21-36906879-36907037,
chr21-36908112-36912037,
chr21-36912728-36913168,
chr21-36913831-36916029,
chr21-36916572-36919027,
chr21-36921025-36921843,
chr21-36922598-36923152,
chr21-36924393-36924624,
chr21-36925188-36930260,
chr21-36931558-36932127,
chr21-36932869-36933269,
chr21-36933777-36933972,
chr21-36936430-36937373,
chr21-36938461-36938855,
chr21-36939198-36940146,
chr21-36940753-36941319,
chr21-36941642-36942402,
chr21-36945889-36946126,
chr21-36946840-36947402,
chr21-36947671-36947946,
chr21-36949217-36949518,
-
Co-expression with cohesin genes Rho = 0.3712
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.458
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.852
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,Keratinocytes192627,GM12892,K1,hTERT-HME1,Olfactory,Hepatocyte-H9,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,SU-DHL-2,H9-hESC,NCI-H1437,iPSC,REC-1,ARPE-19,HCT-116,OCI-AML-3,Hep-G2,HT-1197,H1-hESC,HT-1376,GM19238,Motor-Neuron,MSLCL,HUES64,SU-DHL-4,CyT49-hESC,HUVEC,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,CyT49-Gut,CC-2551,HAP1,HFF-hTERT,MCF7-FASR
- Related loop:
chr21:27500000-27525000~~chr21:36125000-36150000,
chr21:34350000-34375000~~chr21:36125000-36150000,
chr21:36122381-36123542~~chr21:36140871-36142703,
chr21:36122898-36124126~~chr21:36134610-36136702,
chr21:36125000-36150000~~chr21:36225000-36250000,
chr21:36125000-36150000~~chr21:36300000-36325000,
chr21:36125000-36150000~~chr21:36325000-36350000,
chr21:36125000-36150000~~chr21:36350000-36375000,
chr21:36125000-36150000~~chr21:36375000-36400000,
chr21:36125000-36150000~~chr21:36500000-36525000,
chr21:36125000-36150000~~chr21:36575000-36600000,
chr21:36125000-36150000~~chr21:36625000-36650000,
chr21:36125000-36150000~~chr21:36675000-36700000,
chr21:36125000-36150000~~chr21:36900000-36925000,
chr21:36125000-36150000~~chr21:36925000-36950000,
chr21:36125000-36150000~~chr21:38150000-38175000,
chr21:36125000-36150000~~chr21:38325000-38350000,
chr21:36125000-36150000~~chr21:38350000-38375000,
chr21:36140628-36142797~~chr21:36208896-36211059,
chr21:36140628-36142797~~chr21:36329784-36332238,
chr21:36140628-36142797~~chr21:36388297-36390535,
chr21:36140648-36142704~~chr21:36389208-36390546,
chr21:36140770-36142598~~chr21:36208928-36210883,
chr21:36140783-36142792~~chr21:36329776-36331881,
chr21:36140783-36142792~~chr21:36388547-36390538,
chr21:36140789-36142775~~chr21:36208898-36210957,
chr21:36140789-36142775~~chr21:36329509-36332676,
chr21:36140792-36142611~~chr21:36208845-36210808,
chr21:36140792-36142611~~chr21:36330014-36331898,
chr21:36140799-36142667~~chr21:36329820-36331841,
chr21:36140799-36142837~~chr21:36208339-36210839,
chr21:36140799-36142837~~chr21:36329790-36332543,
chr21:36140808-36142792~~chr21:36208893-36211062,
chr21:36140808-36142792~~chr21:36389186-36390767,
chr21:36140808-36142792~~chr21:36419122-36421037,
chr21:36140818-36142825~~chr21:36208180-36210735,
chr21:36140822-36142823~~chr21:36208825-36210883,
chr21:36140822-36142823~~chr21:36329998-36331844,
chr21:36140824-36142795~~chr21:36208849-36210862,
chr21:36140824-36142795~~chr21:36329821-36332549,
chr21:36140824-36142795~~chr21:36389196-36390710,
chr21:36140824-36142795~~chr21:36419273-36421104,
chr21:36140828-36142593~~chr21:36208784-36210767,
chr21:36140829-36142646~~chr21:36389162-36390561,
chr21:36140830-36142847~~chr21:36329991-36331896,
chr21:36140830-36142847~~chr21:36389185-36390513,
chr21:36140835-36142753~~chr21:36388314-36390557,
chr21:36140836-36142645~~chr21:36208979-36210847,
chr21:36140837-36142525~~chr21:36208955-36210590,
chr21:36140837-36142525~~chr21:36330185-36331807,
chr21:36140837-36142525~~chr21:36389208-36390500,
chr21:36140838-36142714~~chr21:36208696-36210781,
chr21:36140838-36142724~~chr21:36330105-36331857,
chr21:36140838-36142786~~chr21:36208808-36211018,
chr21:36140838-36142786~~chr21:36329955-36332030,
chr21:36140838-36142786~~chr21:36388412-36390522,
chr21:36140843-36142531~~chr21:36208942-36210568,
chr21:36140848-36142815~~chr21:36208865-36210865,
chr21:36140848-36142815~~chr21:36329998-36332133,
chr21:36140849-36142584~~chr21:36208920-36210789,
chr21:36140850-36142837~~chr21:36208890-36210845,
chr21:36140850-36142837~~chr21:36329788-36331839,
chr21:36140851-36142527~~chr21:36330219-36331784,
chr21:36140852-36142557~~chr21:36208778-36210979,
chr21:36140852-36142574~~chr21:36330027-36331746,
chr21:36140857-36142570~~chr21:36330220-36331778,
chr21:36140862-36142780~~chr21:36208188-36210796,
chr21:36140863-36142602~~chr21:36208770-36210834,
chr21:36140866-36142633~~chr21:36208896-36210832,
chr21:36140866-36142633~~chr21:36330006-36331764,
chr21:36140870-36142745~~chr21:36209005-36210744,
chr21:36140870-36142745~~chr21:36330021-36331732,
chr21:36140871-36142703~~chr21:36208897-36210863,
chr21:36140871-36142703~~chr21:36330000-36331880,
chr21:36140877-36142726~~chr21:36330374-36331962,
chr21:36140896-36142511~~chr21:36330240-36331785,
chr21:36150000-36175000~~chr21:36300000-36325000,
chr21:36150000-36175000~~chr21:36325000-36350000,
chr21:36150000-36175000~~chr21:36375000-36400000,
chr21:36150000-36175000~~chr21:39175000-39200000,
chr21:36150000-36175000~~chr21:46175000-46200000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE95015, 4DNFITUOMFUQ, ENCSR852KQC, 4DNFIDSWKFF5, 4DNFIZ4F74QR, 4DNFI7H4II2V, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, GSE99541, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, 4DNFIAWVDQ8C, ENCSR305RTT, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, ENCSR033GUP, 4DNFIQWD8ZYD, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, 4DNFIOX3BGNE, ENCSR478BMT, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, Direct, ENCSR314HAC, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIBRSIPE4, 4DNFIR8OU6QJ, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIF2D3TL9, 4DNFIFHU75I5, ENCSR123UVP, 4DNFIL9M97T2, 4DNFI3A3VYWU, 4DNFIM2BMJ33, 4DNFIX4PJKXZ, 4DNFIALNLR78, 4DNFIBY3UHJB, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, ENCSR255XYX, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, ENCSR933UZH, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, 4DNFI5SUHCGZ, ENCSR545YBD, ENCSR866FWQ, 4DNFI6EIFUZI, GSE111537, ENCSR381DCY, ENCSR981FNA, 4DNFIOUSETUP, ENCSR752QCX, ENCSR128RPG, 4DNFISTWNV9C, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFIOCW5AEM, 4DNFIC3HAU11, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFIP71EWXC, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
-
Involved cell types for DEG evidence: U2OS,CMK
- Cohesin-DEGs, number of studies: 2
- Cohesin-DEGs, study: GSE154086,GSE89799
- Cohesin-DEGs, subunit: Rad21,SA2