Deatailed information for gene ENSG00000160181
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010426
- Gene Symbol: TFF2
- Ensembl ID: ENSG00000160181
-
Gene locus: chr21:42346356-42350994
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction
- Regulatory cohesin (double-evidenced):
chr21-41649662-41650037,
chr21-41650707-41652356,
chr21-41653070-41654701,
chr21-41656820-41657981,
chr21-41658412-41661789,
chr21-41662180-41667516,
chr21-41667934-41670919,
chr21-41671179-41674646,
chr21-42342241-42343827,
chr21-42344053-42344672,
chr21-42346561-42348316,
chr21-42348863-42350160,
chr21-42350423-42353086,
chr21-42422915-42428748,
chr21-42429069-42429373,
chr21-42429892-42431565,
chr21-42432008-42432290,
chr21-42433805-42434474,
chr21-42434904-42435230,
chr21-42436840-42441137,
chr21-42442018-42442307,
chr21-42443007-42454584,
chr21-42799515-42801184,
chr21-42801570-42802027,
chr21-42804198-42804619,
chr21-42806323-42807117,
chr21-42807469-42808220,
chr21-42809607-42810029,
chr21-42810534-42811625,
chr21-42812043-42812143,
chr21-42812479-42812787,
chr21-42815294-42815581,
chr21-42816699-42821466,
chr21-43167531-43179410,
chr21-43179782-43180289,
chr21-43180997-43181922,
chr21-43186619-43189146,
chr21-43189488-43189736,
chr21-43190641-43195980,
chr21-43196363-43198075,
chr21-43202414-43202849,
chr21-43203180-43204296,
chr21-43205526-43206063,
chr21-43206324-43207655,
chr21-43207866-43208349,
chr21-43208557-43212285,
chr21-43311036-43327583,
chr21-43328508-43351938,
-
Co-expression with cohesin genes Rho = 0.0516
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.979
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.837
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: MCF-7,GM12878,K-562,TAMR-MCF7,H1-hESC,HeLa-S3
- Related loop:
chr21:41650000-41675000~~chr21:42350000-42375000,
chr21:42325000-42350000~~chr21:42425000-42450000,
chr21:42325000-42350000~~chr21:42800000-42825000,
chr21:42350000-42375000~~chr21:43175000-43200000,
chr21:42350000-42375000~~chr21:43200000-43225000,
chr21:42350000-42375000~~chr21:43325000-43350000,
- Cohesin-loop type: HiC,Direct
- Cohesin-loop study:
4DNFI9YAVTI1, 4DNFIPAF4PYT, 4DNFIQVMVRP6, 4DNFIWZEN3FF, Direct, GSE118716, 4DNFIDBIEXI7, 4DNFI1UEG1HD, 4DNFIJWBWE41, 4DNFI7H4II2V, ENCSR410MDC
- Cohesin-loop subunit: Other
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
-
Involved cell types for DEG evidence: MCF-7
- Cohesin-DEGs, number of studies: 2
- Cohesin-DEGs, study: GSE59908
- Cohesin-DEGs, subunit: Rad21