Deatailed information for gene ENSG00000160182
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010427
- Gene Symbol: TFF1
- Ensembl ID: ENSG00000160182
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Gene locus: chr21:42362281-42366535
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction
- Regulatory cohesin (double-evidenced):
chr21-41649662-41650037,
chr21-41650707-41652356,
chr21-41653070-41654701,
chr21-41656820-41657981,
chr21-41658412-41661789,
chr21-41662180-41667516,
chr21-41667934-41670919,
chr21-41671179-41674646,
chr21-42358219-42359271,
chr21-42359518-42361729,
chr21-42361994-42368140,
chr21-42369574-42378333,
chr21-42443007-42454584,
chr21-43167531-43179410,
chr21-43179782-43180289,
chr21-43180997-43181922,
chr21-43186619-43189146,
chr21-43189488-43189736,
chr21-43190641-43195980,
chr21-43196363-43198075,
chr21-43202414-43202849,
chr21-43203180-43204296,
chr21-43205526-43206063,
chr21-43206324-43207655,
chr21-43207866-43208349,
chr21-43208557-43212285,
chr21-43311036-43327583,
chr21-43328508-43351938,
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Co-expression with cohesin genes Rho = 0.0711
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.974
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.765
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: MCF-7,NCI-H1437,GM12878,K-562,TAMR-MCF7,H1-hESC,K1
- Related loop:
chr21:41650000-41675000~~chr21:42350000-42375000,
chr21:42350000-42375000~~chr21:43175000-43200000,
chr21:42350000-42375000~~chr21:43200000-43225000,
chr21:42350000-42375000~~chr21:43325000-43350000,
chr21:42359657-42361508~~chr21:42448798-42450961,
chr21:42359709-42361461~~chr21:42448781-42450921,
chr21:42359717-42361558~~chr21:42448842-42450946,
chr21:42359923-42361354~~chr21:42449161-42450786,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
ENCSR000FDB, ENCSR338WUS, Direct, ENCSR314HAC, GSE118716, ENCSR833CMG, 4DNFI1UEG1HD, 4DNFIJWBWE41, ENCSR410MDC
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
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Involved cell types for DEG evidence: MCF-7,HeLa-S3
- Cohesin-DEGs, number of studies: 2
- Cohesin-DEGs, study: GSE38252,GSE130558
- Cohesin-DEGs, subunit: WAPL,SMC3