Deatailed information for gene ENSG00000160183
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010428
- Gene Symbol: TMPRSS3
- Ensembl ID: ENSG00000160183
-
Gene locus: chr21:42371886-42396052
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-41600668-41607029,
chr21-41607264-41617134,
chr21-41617741-41618159,
chr21-41619036-41619135,
chr21-41620001-41623327,
chr21-41649662-41650037,
chr21-41650707-41652356,
chr21-41653070-41654701,
chr21-41656820-41657981,
chr21-41658412-41661789,
chr21-41662180-41667516,
chr21-41667934-41670919,
chr21-41671179-41674646,
chr21-42103416-42126825,
chr21-42127155-42127810,
chr21-42128488-42129619,
chr21-42130648-42131154,
chr21-42133171-42133790,
chr21-42135118-42136218,
chr21-42136531-42136713,
chr21-42136966-42138370,
chr21-42139645-42142559,
chr21-42143139-42149312,
chr21-42149675-42151617,
chr21-42152798-42155831,
chr21-42156081-42158150,
chr21-42158837-42159271,
chr21-42159533-42167922,
chr21-42168175-42168574,
chr21-42169121-42169273,
chr21-42171081-42172120,
chr21-42172666-42173562,
chr21-42173962-42174405,
chr21-42299343-42300483,
chr21-42300983-42302568,
chr21-42302945-42303453,
chr21-42304539-42307451,
chr21-42307683-42313987,
chr21-42314400-42316186,
chr21-42316662-42318793,
chr21-42319099-42320523,
chr21-42320786-42322135,
chr21-42361994-42368140,
chr21-42369574-42378333,
chr21-42379075-42386730,
chr21-42387088-42387861,
chr21-42388368-42389897,
chr21-42390708-42391993,
chr21-42392268-42394091,
chr21-42395908-42396729,
chr21-42397019-42398856,
chr21-42399356-42399471,
chr21-42400535-42400843,
chr21-42414328-42417910,
chr21-42422915-42428748,
chr21-42443007-42454584,
chr21-42499096-42500557,
chr21-42501424-42501674,
chr21-42502080-42502217,
chr21-42502708-42504189,
chr21-42504444-42505658,
chr21-42508152-42508427,
chr21-42509210-42509582,
chr21-42512399-42517747,
chr21-42517993-42518929,
chr21-42520617-42521491,
chr21-42521907-42522162,
chr21-42522739-42523588,
chr21-42524067-42525788,
chr21-42534381-42538581,
chr21-42799515-42801184,
chr21-42801570-42802027,
chr21-42804198-42804619,
chr21-42806323-42807117,
chr21-42807469-42808220,
chr21-42809607-42810029,
chr21-42810534-42811625,
chr21-42812043-42812143,
chr21-42812479-42812787,
chr21-42815294-42815581,
chr21-42816699-42821466,
chr21-43167531-43179410,
chr21-43179782-43180289,
chr21-43180997-43181922,
chr21-43186619-43189146,
chr21-43189488-43189736,
chr21-43190641-43195980,
chr21-43196363-43198075,
chr21-43202414-43202849,
chr21-43203180-43204296,
chr21-43205526-43206063,
chr21-43206324-43207655,
chr21-43207866-43208349,
chr21-43208557-43212285,
chr21-43311036-43327583,
chr21-43328508-43351938,
-
Co-expression with cohesin genes Rho = -0.0957
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.670
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.810
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: TAMR-MCF7,Keratinocytes192627,K1,GM19239,HEK293T,MCF-7,GM12891,GM12878,K-562,A-549,PAEC,SU-DHL-2,KU-19-19,NCI-H1437,ARPE-19,Hep-G2,Kelly,H1-hESC,GM19238,MSLCL,GM19240,SU-DHL-4,Skin-Fibroblast
- Related loop:
chr21:41600000-41625000~~chr21:42375000-42400000,
chr21:41650000-41675000~~chr21:42350000-42375000,
chr21:42125000-42150000~~chr21:42375000-42400000,
chr21:42144207-42146848~~chr21:42380765-42382404,
chr21:42144411-42146838~~chr21:42379115-42382711,
chr21:42144457-42146811~~chr21:42380286-42382659,
chr21:42144599-42146873~~chr21:42380621-42382601,
chr21:42144776-42146791~~chr21:42380859-42382357,
chr21:42144995-42146449~~chr21:42380974-42382225,
chr21:42150000-42175000~~chr21:42375000-42400000,
chr21:42163609-42165687~~chr21:42380859-42382357,
chr21:42163812-42165464~~chr21:42380774-42382379,
chr21:42300000-42325000~~chr21:42400000-42425000,
chr21:42308252-42310733~~chr21:42380708-42382353,
chr21:42308480-42310797~~chr21:42380801-42382413,
chr21:42308486-42310572~~chr21:42380774-42382379,
chr21:42308495-42311005~~chr21:42379115-42382711,
chr21:42350000-42375000~~chr21:43175000-43200000,
chr21:42350000-42375000~~chr21:43200000-43225000,
chr21:42350000-42375000~~chr21:43325000-43350000,
chr21:42375000-42400000~~chr21:42800000-42825000,
chr21:42376023-42377763~~chr21:42448830-42450945,
chr21:42376040-42377995~~chr21:42448845-42450957,
chr21:42376051-42377691~~chr21:42448842-42450946,
chr21:42376058-42377983~~chr21:42448798-42450961,
chr21:42376165-42377700~~chr21:42449311-42450852,
chr21:42376176-42377607~~chr21:42449161-42450786,
chr21:42376206-42377802~~chr21:42449017-42451480,
chr21:42376251-42377642~~chr21:42449010-42450957,
chr21:42376319-42377570~~chr21:42449201-42450804,
chr21:42379115-42382711~~chr21:42448763-42451324,
chr21:42379115-42382711~~chr21:42536098-42538505,
chr21:42380286-42382659~~chr21:42448861-42450972,
chr21:42380494-42382722~~chr21:42448782-42450960,
chr21:42380494-42382722~~chr21:42535556-42538484,
chr21:42380497-42382547~~chr21:42448828-42450945,
chr21:42380717-42382804~~chr21:42449093-42451498,
chr21:42380746-42382516~~chr21:42449031-42450943,
chr21:42380793-42382292~~chr21:42449091-42451494,
chr21:42380842-42382336~~chr21:42449125-42450914,
chr21:42380859-42382357~~chr21:42448814-42450934,
chr21:42380883-42382301~~chr21:42449239-42450901,
chr21:42380903-42382335~~chr21:42449017-42451480,
chr21:42392339-42394372~~chr21:42422767-42426562,
chr21:42392456-42394336~~chr21:42414406-42416483,
chr21:42392456-42394336~~chr21:42422709-42426547,
chr21:42400000-42425000~~chr21:42500000-42525000,
chr21:42400000-42425000~~chr21:42800000-42825000,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIDJ2JZ7Q, GSE118716, ENCSR499RVD, GSE108787, ENCSR146FPM, GSE103148, ENCSR410MDC, ENCSR732QOH, ENCSR668RDP, 4DNFIJWBWE41, ENCSR981FNA, ENCSR587DSF, ENCSR452NHL, 4DNFIL9M97T2, ENCSR128RPG, GSE52457, ENCSR658RQQ, ENCSR312TUD, ENCSR299VMZ, ENCSR314HAC, ENCSR479MTN, Direct, 4DNFI1UEG1HD, GSE44267, ENCSR255XYX, ENCSR000FDB, ENCSR404HWQ, ENCSR110JOO, ENCSR338WUS, ENCSR527RXH, ENCSR833CMG
- Cohesin-loop subunit: SMC1,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: MCF-7,HeLa,U2OS,MCF-10A
- Cohesin-DEGs, number of studies: 5
- Cohesin-DEGs, study: GSE59908,GSE71420,GSE154086,GSE89799
- Cohesin-DEGs, subunit: Rad21,SMC3