Deatailed information for gene ENSG00000160201
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010437
- Gene Symbol: U2AF1
- Ensembl ID: ENSG00000160201
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Gene locus: chr21:43092955-43107570
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-42574597-42575565,
chr21-42576721-42576991,
chr21-42578056-42578346,
chr21-42578723-42581320,
chr21-42581763-42582576,
chr21-42583402-42584657,
chr21-42586456-42597158,
chr21-42597733-42599089,
chr21-42599440-42600439,
chr21-42847259-42856312,
chr21-42856928-42857550,
chr21-42858264-42858922,
chr21-42859132-42861293,
chr21-42861653-42864957,
chr21-42865222-42866633,
chr21-42867885-42870709,
chr21-42872006-42873778,
chr21-42898938-42900986,
chr21-42901231-42902142,
chr21-42903879-42905128,
chr21-42905606-42906786,
chr21-42908791-42909506,
chr21-42909724-42911164,
chr21-42912357-42914258,
chr21-42914488-42914837,
chr21-42915076-42915684,
chr21-42916003-42917086,
chr21-42917709-42919392,
chr21-42919813-42921376,
chr21-42921622-42928571,
chr21-43000878-43004167,
chr21-43005014-43005958,
chr21-43006547-43007242,
chr21-43007563-43008111,
chr21-43008975-43009699,
chr21-43011079-43011547,
chr21-43012278-43013148,
chr21-43016030-43017256,
chr21-43018084-43019388,
chr21-43020175-43023005,
chr21-43023655-43024103,
chr21-43024487-43026869,
chr21-43086209-43088335,
chr21-43088806-43089146,
chr21-43089504-43089828,
chr21-43091108-43091423,
chr21-43092075-43092675,
chr21-43095157-43095416,
chr21-43099852-43100255,
chr21-43104309-43104688,
chr21-43106709-43112150,
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Co-expression with cohesin genes Rho = 0.3417
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.315
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.879
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: MCF-7,SARS-Cov2-olfactory,HCT-116,GM12878,KBM-7,H1-hESC,HAP1,HFFc6,MCF7-FASR,H9-hESC
- Related loop:
chr21:42575000-42600000~~chr21:43100000-43125000,
chr21:42850000-42875000~~chr21:43100000-43125000,
chr21:42900000-42925000~~chr21:43100000-43125000,
chr21:43000000-43025000~~chr21:43100000-43125000,
chr21:6475000-6500000~~chr21:43075000-43100000,
- Cohesin-loop type: HiC,Direct
- Cohesin-loop study:
4DNFI1E6NJQJ, 4DNFI9ZWZ5BS, 4DNFI7XAZNNQ, 4DNFII6AN691, Direct, 4DNFIMROE6N4, GSE118716, 4DNFIP71EWXC, 4DNFIFLJLIS5, 4DNFILIM6FDL, 4DNFIS5F6EBL, 4DNFI5SUHCGZ, 4DNFII84FBKM, 4DNFIT96Z365, 4DNFIIMZB6Y9
- Cohesin-loop subunit: Other
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: K-562,U2OS
- Cohesin-DEGs, number of studies: 3
- Cohesin-DEGs, study: GSE131448,GSE89799
- Cohesin-DEGs, subunit: Rad21,SA2