Deatailed information for gene ENSG00000160284

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  • Basic information
  • CohesinDB ID: CDBG00010458
  • Gene Symbol: SPATC1L
  • Ensembl ID: ENSG00000160284
  • Gene locus: chr21:46161147-46184476 Strand: -
  • Gene type: protein_coding
  • Double-evidenced cohesin related CRMs
  • Whether cohesin-related CRMs (double-evidenced): True
  • All evidenced type: Interaction,DEGs
  • Regulatory cohesin (double-evidenced): chr21-46149160-46156934, chr21-46157182-46162882, chr21-46163984-46164675, chr21-46168156-46168934, chr21-46169153-46171141, chr21-46171924-46173761, chr21-46177897-46178257, chr21-46178694-46178929, chr21-46179577-46186632, chr21-46186833-46187560, chr21-46187919-46196339,
  • Co-expression with cohesin genes Rho = 0.3328 FDR = 0.0000
    (Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
  • Tissue specificity
  • Gene expression across tissues (TPM):
  • Tissue specificity of gene (Gini-coefficient): 0.329
    0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
  • Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.826
    0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
  • Cohesin-loop evidence
  • Whether has cohesin-loop: True
  • Involved cell types for loop evidence: H9-hESC,GM12878,H1-hESC
  • Related loop: chr21:36150000-36175000~~chr21:46175000-46200000, chr21:44075000-44100000~~chr21:46175000-46200000,
  • Cohesin-loop type: HiC,Direct
  • Cohesin-loop study: Direct, 4DNFIJ8JKKWJ, 4DNFI1UEG1HD, 4DNFIIMZB6Y9, ENCSR410MDC
  • Cohesin-loop subunit: Other
  • Cohesin-DEGs evidence
  • Whether cohesin DEGs: True
  • Involved cell types for DEG evidence: HL-60,SLK,P3HR-1,MCF-10A,U2OS
  • Cohesin-DEGs, number of studies: 6
  • Cohesin-DEGs, study: GSE140651,GSE101921,GSE131581,GSE138937,GSE89799
  • Cohesin-DEGs, subunit: CTCF,SMC1,Rad21,SA2
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