Deatailed information for gene ENSG00000160299
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010463
- Gene Symbol: PCNT
- Ensembl ID: ENSG00000160299
-
Gene locus: chr21:46324155-46445769
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-46141781-46148753,
chr21-46284943-46285049,
chr21-46285330-46287984,
chr21-46313333-46319898,
chr21-46320099-46321019,
chr21-46321556-46327387,
chr21-46327742-46329074,
chr21-46331010-46331108,
chr21-46332516-46334205,
chr21-46334427-46334742,
chr21-46335907-46336270,
chr21-46337581-46338322,
chr21-46338663-46339476,
chr21-46342635-46342853,
chr21-46344216-46344846,
chr21-46345175-46348858,
chr21-46349192-46349760,
chr21-46350702-46351423,
chr21-46351700-46353072,
chr21-46353313-46359214,
chr21-46360240-46360862,
chr21-46361998-46362313,
chr21-46362947-46363290,
chr21-46363641-46365053,
chr21-46365321-46370918,
chr21-46371358-46373964,
chr21-46374274-46375262,
chr21-46375589-46377385,
chr21-46379126-46379439,
chr21-46379763-46380641,
chr21-46381146-46381978,
chr21-46382468-46382957,
chr21-46383231-46384200,
chr21-46384475-46384979,
chr21-46385867-46389547,
chr21-46389812-46390392,
chr21-46390664-46392020,
chr21-46392288-46395224,
chr21-46396119-46399536,
chr21-46400660-46401091,
chr21-46401300-46402144,
chr21-46402358-46405013,
chr21-46407368-46407668,
chr21-46409280-46410234,
chr21-46411345-46413444,
chr21-46413887-46415371,
chr21-46416057-46416894,
chr21-46418342-46419084,
chr21-46419432-46423022,
chr21-46423224-46424657,
chr21-46424988-46431179,
chr21-46431468-46432849,
chr21-46433078-46433346,
chr21-46434245-46438584,
chr21-46439258-46439550,
chr21-46439886-46440698,
chr21-46441382-46442462,
chr21-46442897-46444478,
chr21-46445241-46445707,
chr21-46446094-46446552,
chr21-46447746-46448786,
-
Co-expression with cohesin genes Rho = 0.4417
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.343
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.897
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: Skin-Fibroblast,Hep-G2,HT-1197,Kelly,H1-hESC,DU145,SU-DHL-2,PAEC,K1,hTERT-HME1,SU-DHL-4,Hepatocyte-H9
- Related loop:
chr21:46146626-46148368~~chr21:46324586-46327028,
chr21:46146642-46148386~~chr21:46324608-46326836,
chr21:46284828-46287850~~chr21:46324624-46326392,
chr21:46284891-46287117~~chr21:46325193-46327052,
chr21:46284913-46287579~~chr21:46323099-46326350,
chr21:46284994-46287562~~chr21:46323170-46326814,
chr21:46285004-46287523~~chr21:46324190-46326305,
chr21:46285202-46287572~~chr21:46324782-46326051,
chr21:46285204-46287304~~chr21:46324596-46326067,
chr21:46285206-46287083~~chr21:46324674-46326343,
chr21:46285212-46287543~~chr21:46321861-46326303,
chr21:46285216-46286892~~chr21:46324785-46326845,
chr21:46285222-46287087~~chr21:46324856-46327070,
chr21:46285272-46287549~~chr21:46324181-46326111,
chr21:46347006-46348971~~chr21:46436325-46437620,
chr21:46354938-46358026~~chr21:46387976-46391139,
- Cohesin-loop type: Direct,ChIAPET
- Cohesin-loop study:
ENCSR128RPG, ENCSR991JXX, ENCSR732QOH, ENCSR658RQQ, Direct, ENCSR314HAC, ENCSR668RDP, ENCSR381DCY, ENCSR386KHY, ENCSR146FPM, ENCSR672RHL, GSE103148, ENCSR587DSF
- Cohesin-loop subunit: SMC1,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: HAP1,HeLa-S3,P3HR-1
- Cohesin-DEGs, number of studies: 5
- Cohesin-DEGs, study: GSE140651,GSE126635,GSE108869,GSE130558
- Cohesin-DEGs, subunit: WAPL,CTCF,SMC1