Deatailed information for gene ENSG00000160310
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00010466
- Gene Symbol: PRMT2
- Ensembl ID: ENSG00000160310
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Gene locus: chr21:46635594-46665117
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-46141781-46148753,
chr21-46149160-46156934,
chr21-46223334-46230482,
chr21-46550355-46552742,
chr21-46596141-46599655,
chr21-46620869-46623000,
chr21-46633183-46633466,
chr21-46634382-46636748,
chr21-46637461-46637990,
chr21-46638280-46640885,
chr21-46641389-46641941,
chr21-46642699-46643903,
chr21-46644903-46645378,
chr21-46645871-46647210,
chr21-46648416-46649815,
chr21-46650027-46650395,
chr21-46650617-46652028,
chr21-46656021-46656221,
chr21-46658601-46659062,
chr21-46660252-46664093,
chr21-46664379-46664904,
chr21-46666370-46668508,
chr21-46669397-46669669,
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Co-expression with cohesin genes Rho = 0.5579
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.252
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.754
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: Hep-G2,hTERT-HME1,GM12891,H1-hESC
- Related loop:
chr21:46143023-46144677~~chr21:46639346-46640584,
chr21:46152495-46154271~~chr21:46639226-46640751,
chr21:46224751-46225933~~chr21:46639346-46640584,
chr21:46226574-46227839~~chr21:46635152-46636811,
chr21:46550822-46552528~~chr21:46639252-46640633,
chr21:46598388-46600289~~chr21:46634449-46636635,
chr21:46621725-46623434~~chr21:46635155-46636377,
- Cohesin-loop type: Direct,ChIAPET
- Cohesin-loop study:
ENCSR991JXX, Direct, ENCSR299VMZ, ENCSR146FPM, ENCSR587DSF
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: HL-60,HPC,HCT116-mAID,P3HR-1,K-562,MCF-10A,CordBlood
- Cohesin-DEGs, number of studies: 8
- Cohesin-DEGs, study: GSE140651,GSE74824,GSE101921,GSE131581,GSE119828,GSE131448,GSE106886
- Cohesin-DEGs, subunit: SA2,CTCF,SMC1,Rad21,CdLS