Deatailed information for gene ENSG00000166979
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00011991
- Gene Symbol: EVA1C
- Ensembl ID: ENSG00000166979
-
Gene locus: chr21:32412684-32515397
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-31274283-31275119,
chr21-31277324-31277646,
chr21-31279884-31280101,
chr21-31281565-31284764,
chr21-31284970-31285795,
chr21-31290321-31290795,
chr21-31291514-31291905,
chr21-31292441-31293180,
chr21-31293609-31296107,
chr21-31297445-31297668,
chr21-31298480-31299818,
chr21-32027404-32027780,
chr21-32030104-32030639,
chr21-32032967-32033443,
chr21-32034224-32034628,
chr21-32038190-32038608,
chr21-32043695-32044823,
chr21-32046552-32047130,
chr21-32049756-32050545,
chr21-32299751-32300868,
chr21-32301692-32301838,
chr21-32304893-32304989,
chr21-32305776-32306803,
chr21-32307314-32307797,
chr21-32308617-32310741,
chr21-32311435-32312117,
chr21-32312390-32312669,
chr21-32313137-32313329,
chr21-32314800-32315445,
chr21-32315753-32317229,
chr21-32317515-32318325,
chr21-32319081-32319441,
chr21-32319827-32320459,
chr21-32320782-32321118,
chr21-32321609-32323171,
chr21-32323561-32324126,
chr21-32324577-32324835,
chr21-32401093-32405487,
chr21-32405735-32406834,
chr21-32408217-32408697,
chr21-32409703-32410211,
chr21-32410923-32416711,
chr21-32417894-32418785,
chr21-32420222-32420681,
chr21-32422799-32425391,
chr21-32425673-32427854,
chr21-32428298-32429487,
chr21-32429954-32430285,
chr21-32430765-32431305,
chr21-32432457-32433877,
chr21-32434120-32434591,
chr21-32435230-32435597,
chr21-32436661-32438393,
chr21-32438930-32439429,
chr21-32442062-32443561,
chr21-32445988-32446256,
chr21-32446555-32447370,
chr21-32447743-32448733,
chr21-32449309-32449997,
chr21-32450290-32453267,
chr21-32455431-32458336,
chr21-32458592-32459810,
chr21-32460801-32461622,
chr21-32462635-32464978,
chr21-32465888-32466157,
chr21-32467324-32467836,
chr21-32468636-32469297,
chr21-32470295-32471149,
chr21-32471386-32471935,
chr21-32472299-32473135,
chr21-32473670-32479773,
chr21-32480464-32480858,
chr21-32482032-32482291,
chr21-32482533-32483360,
chr21-32483950-32485031,
chr21-32485253-32485688,
chr21-32486141-32486482,
chr21-32491080-32492695,
chr21-32492896-32494129,
chr21-32494469-32496274,
chr21-32498609-32500453,
chr21-32501923-32502381,
chr21-32502858-32503479,
chr21-32506555-32507085,
chr21-32507382-32508856,
chr21-32509210-32510394,
chr21-32511129-32511347,
chr21-32514665-32515061,
chr21-32515682-32517377,
chr21-32517976-32518345,
chr21-32519053-32526591,
chr21-32551895-32552608,
chr21-32555986-32556336,
chr21-32559531-32560122,
chr21-32560770-32563200,
chr21-32563471-32563819,
chr21-32565876-32566407,
chr21-32566765-32568083,
chr21-32569005-32571301,
chr21-32571677-32572067,
chr21-32572278-32573787,
chr21-32574949-32576472,
chr21-32576694-32579657,
chr21-32580005-32580573,
chr21-32580904-32582331,
chr21-32583026-32584806,
chr21-32585090-32585613,
chr21-32586300-32587559,
chr21-32590405-32590668,
chr21-32590870-32591197,
chr21-32592176-32593983,
chr21-32594251-32594977,
chr21-32595506-32596052,
chr21-32596424-32597923,
chr21-32598775-32602954,
chr21-32603193-32603581,
chr21-32604431-32605130,
chr21-32610128-32610562,
chr21-32610963-32613801,
chr21-32614942-32615265,
chr21-32618034-32618378,
chr21-32618831-32619540,
chr21-32620088-32620453,
chr21-32621102-32621530,
chr21-32624498-32625154,
chr21-32726512-32729587,
chr21-32732552-32732879,
chr21-32824831-32828372,
chr21-32830402-32830634,
chr21-32831636-32833765,
chr21-32834854-32835342,
chr21-32836285-32836542,
chr21-32844499-32845578,
chr21-32846527-32846785,
chr21-33018853-33032029,
chr21-33032493-33034874,
chr21-33035105-33037170,
chr21-33039667-33039909,
chr21-33040959-33041685,
chr21-33042060-33043831,
chr21-33046659-33047090,
chr21-33047338-33047839,
chr21-33049543-33050194,
chr21-33176533-33177231,
chr21-33178927-33179239,
chr21-33180031-33180867,
chr21-33181665-33182455,
chr21-33183559-33184328,
chr21-33185051-33185236,
chr21-33185475-33185847,
chr21-33186452-33186919,
chr21-33189336-33190586,
chr21-33191132-33191643,
chr21-33192567-33193025,
chr21-33193411-33193657,
chr21-33194152-33195061,
chr21-33195338-33206151,
chr21-33278068-33278366,
chr21-33278760-33279199,
chr21-33279478-33279883,
chr21-33281091-33281795,
chr21-33282298-33282619,
chr21-33283111-33284448,
chr21-33285676-33297310,
chr21-33297831-33303232,
-
Co-expression with cohesin genes Rho = 0.4479
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.433
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.896
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,Keratinocytes192627,K1,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,MCF-7,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,H1-Trophectoderm,H9-hESC,KU-19-19,iPSC,Liver,ARPE-19,HCT-116,OCI-AML-3,REC-1,Hep-G2,HT-1197,Kelly,H1-hESC,HCC1599,Motor-Neuron,U-937,BMEC,HUES64,H1-NPC,CyT49-hESC,HUVEC,HL-60,RT-112,CyT49-endoderm,Skin-Fibroblast,KBM-7,CC-2551,CyT49-Gut,HAP1,HFF-hTERT,MCF7-FASR,U251
- Related loop:
chr21:31275000-31300000~~chr21:32475000-32500000,
chr21:32025000-32050000~~chr21:32450000-32475000,
chr21:32300000-32325000~~chr21:32450000-32475000,
chr21:32400000-32425000~~chr21:32500000-32525000,
chr21:32400000-32425000~~chr21:32550000-32575000,
chr21:32400000-32425000~~chr21:32575000-32600000,
chr21:32400000-32425000~~chr21:32600000-32625000,
chr21:32400000-32425000~~chr21:32725000-32750000,
chr21:32400000-32425000~~chr21:32825000-32850000,
chr21:32400000-32425000~~chr21:33175000-33200000,
chr21:32412413-32413787~~chr21:32599845-32601920,
chr21:32412549-32415746~~chr21:32568763-32570909,
chr21:32412635-32415974~~chr21:32561117-32563575,
chr21:32412635-32415974~~chr21:32568694-32570973,
chr21:32412745-32415761~~chr21:32568706-32571494,
chr21:32412745-32415761~~chr21:32598994-32601796,
chr21:32413227-32415524~~chr21:32568643-32570980,
chr21:32413259-32415823~~chr21:32568723-32570970,
chr21:32413259-32415823~~chr21:32599838-32601801,
chr21:32413356-32415861~~chr21:32561346-32563661,
chr21:32413356-32415861~~chr21:32568729-32570718,
chr21:32413356-32415861~~chr21:32599851-32601933,
chr21:32413407-32415950~~chr21:32561489-32563438,
chr21:32413407-32415950~~chr21:32568683-32570920,
chr21:32413407-32415950~~chr21:32599840-32601796,
chr21:32413601-32416113~~chr21:32561649-32563602,
chr21:32413601-32416113~~chr21:32568755-32571056,
chr21:32413601-32416113~~chr21:32599842-32601842,
chr21:32413701-32415963~~chr21:32561671-32563639,
chr21:32413701-32415963~~chr21:32599805-32601899,
chr21:32413909-32415933~~chr21:32599809-32601807,
chr21:32413950-32415829~~chr21:32600085-32601819,
chr21:32414014-32416231~~chr21:32568659-32570952,
chr21:32414040-32415387~~chr21:32568752-32570914,
chr21:32450000-32475000~~chr21:32575000-32600000,
chr21:32450000-32475000~~chr21:33275000-33300000,
chr21:32475000-32500000~~chr21:32575000-32600000,
chr21:32500000-32525000~~chr21:32600000-32625000,
chr21:32500000-32525000~~chr21:33025000-33050000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE95015, GSE43070, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, 4DNFIDSWKFF5, 4DNFIZ4F74QR, 4DNFI7H4II2V, ENCSR350NJV, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, 4DNFI9VXTBE2, 4DNFIKYXMF1E, 4DNFIWNNO89O, 4DNFIRKGMZRQ, GSE99541, ENCSR668RDP, 4DNFIL5K3MA1, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, 4DNFIJ5DQZVK, 4DNFI6XD6JAQ, 4DNFISPUVQHA, GSE112000, 4DNFI8Y9SRP2, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, 4DNFI7XAZNNQ, GSE105028, 4DNFIBKZK63V, 4DNFIQWD8ZYD, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, GSE126792, 4DNFIOX3BGNE, 4DNFINW9P6XF, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, 4DNFIIMZB6Y9, GSE52457, Direct, ENCSR314HAC, 4DNFIH9U4I7I, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, 4DNFIYJ4TWB8, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIH7TH4MF, 4DNFIT96Z365, 4DNFIH2A7IKF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIBRSIPE4, 4DNFI6CWNUFL, 4DNFI5CGQ46V, 4DNFIR8OU6QJ, 4DNFIE8E4ANZ, GSE120294, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIFHU75I5, 4DNFIYD8LO9Z, 4DNFI15FPSQL, ENCSR444BAR, ENCSR123UVP, 4DNFIL9M97T2, 4DNFIJBJ6QVH, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIM2BMJ33, GSE165038, 4DNFIALNLR78, 4DNFIYDBBSE3, ENCSR386KHY, ENCSR379CII, 4DNFIEJEFCAM, 4DNFIQRTP7NM, ENCSR393LOP, 4DNFI4TJTL7A, GSE125243, 4DNFIPAF4PYT, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR094EIC, GSE58752, ENCSR507AHE, GSE116869, 4DNFI8649RQJ, 4DNFIRZA6EV6, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFIP25GZGA, 4DNFI6EIFUZI, ENCSR866FWQ, 4DNFII6AN691, GSE111537, GSE131580, 4DNFIV239W4L, 4DNFIOUSETUP, 4DNFIXGXD67I, 4DNFISTWNV9C, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFI8JFOAJT, 4DNFIOCW5AEM, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFIP71EWXC, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: CMK,HeLa-S3,MCF-10A
- Cohesin-DEGs, number of studies: 4
- Cohesin-DEGs, study: GSE139845,GSE154086,GSE101921,GSE130558
- Cohesin-DEGs, subunit: WAPL,CTCF,SA2