Deatailed information for gene ENSG00000182362
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00015218
- Gene Symbol: YBEY
- Ensembl ID: ENSG00000182362
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Gene locus: chr21:46286341-46297751
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,
- Regulatory cohesin (double-evidenced):
chr21-46141781-46148753,
chr21-46281755-46282121,
chr21-46282493-46283237,
chr21-46283683-46284511,
chr21-46284943-46285049,
chr21-46285330-46287984,
chr21-46288318-46289027,
chr21-46289414-46300495,
chr21-46301269-46303301,
chr21-46321556-46327387,
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Co-expression with cohesin genes Rho = 0.4639
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.307
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.726
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: Skin-Fibroblast,Hep-G2,HT-1197,Kelly,H1-hESC,DU145,PAEC,K1,hTERT-HME1,Hepatocyte-H9
- Related loop:
chr21:46142465-46144615~~chr21:46285004-46287523,
chr21:46284828-46287850~~chr21:46324624-46326392,
chr21:46284891-46287117~~chr21:46325193-46327052,
chr21:46284913-46287579~~chr21:46323099-46326350,
chr21:46284994-46287562~~chr21:46323170-46326814,
chr21:46285004-46287523~~chr21:46324190-46326305,
chr21:46285202-46287572~~chr21:46324782-46326051,
chr21:46285204-46287304~~chr21:46324596-46326067,
chr21:46285206-46287083~~chr21:46324674-46326343,
chr21:46285212-46287543~~chr21:46321861-46326303,
chr21:46285216-46286892~~chr21:46324785-46326845,
chr21:46285222-46287087~~chr21:46324856-46327070,
chr21:46285272-46287549~~chr21:46324181-46326111,
- Cohesin-loop type: Direct,ChIAPET
- Cohesin-loop study:
ENCSR991JXX, ENCSR732QOH, Direct, ENCSR314HAC, ENCSR668RDP, ENCSR381DCY, ENCSR386KHY, ENCSR146FPM, ENCSR672RHL, GSE103148, ENCSR587DSF
- Cohesin-loop subunit: SMC1,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
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Involved cell types for DEG evidence: K-562,SLK
- Cohesin-DEGs, number of studies: 2
- Cohesin-DEGs, study: GSE138937,GSE131448
- Cohesin-DEGs, subunit: Rad21,SA2