Deatailed information for gene ENSG00000183036
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00015376
- Gene Symbol: PCP4
- Ensembl ID: ENSG00000183036
-
Gene locus: chr21:39867437-39929392
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction
- Regulatory cohesin (double-evidenced):
chr21-38849471-38854263,
chr21-38856453-38857719,
chr21-38858525-38859524,
chr21-38859766-38860539,
chr21-38861132-38861513,
chr21-38862000-38863279,
chr21-38864066-38864405,
chr21-38867234-38867512,
chr21-38869262-38870389,
chr21-38872690-38873110,
chr21-38873491-38873832,
chr21-38874324-38875151,
chr21-39502548-39502970,
chr21-39507373-39507834,
chr21-39509959-39510524,
chr21-39511165-39511517,
chr21-39514883-39522284,
chr21-39522520-39523070,
chr21-39523279-39525034,
chr21-39601006-39602588,
chr21-39604265-39605410,
chr21-39607665-39608007,
chr21-39608787-39609235,
chr21-39609628-39615120,
chr21-39616321-39616816,
chr21-39750744-39751143,
chr21-39762944-39764842,
chr21-39765586-39765815,
chr21-39776876-39777010,
chr21-39787003-39790494,
chr21-39791207-39791882,
chr21-39796085-39796993,
chr21-39863160-39864324,
chr21-39864542-39868722,
chr21-39869137-39870155,
chr21-39880410-39880541,
chr21-39881640-39882899,
chr21-39883106-39883442,
chr21-39884258-39884729,
chr21-39885211-39885800,
chr21-39888414-39888743,
chr21-39889425-39889716,
chr21-39891930-39892227,
chr21-39903482-39903887,
chr21-39908275-39908862,
chr21-39909863-39913124,
chr21-39917286-39917553,
chr21-39919712-39920331,
chr21-39920803-39921032,
chr21-39924824-39925293,
chr21-39925600-39925902,
chr21-39927541-39927780,
chr21-40049939-40050260,
chr21-40050498-40050756,
chr21-40053259-40055664,
chr21-40057804-40058353,
chr21-40059857-40060679,
chr21-40065862-40066154,
chr21-40070140-40071348,
chr21-40072339-40072617,
chr21-40074363-40075414,
chr21-40099908-40100097,
chr21-40109484-40110216,
chr21-40116723-40123569,
chr21-40127723-40128008,
chr21-40133778-40134486,
chr21-40137553-40137697,
chr21-40138649-40139119,
chr21-40139730-40140015,
chr21-40140942-40147745,
chr21-40149386-40149804,
chr21-40278675-40278812,
chr21-40282274-40282612,
chr21-40283506-40283952,
chr21-40290340-40290592,
chr21-40291252-40291932,
chr21-40292808-40293388,
chr21-40298897-40299732,
chr21-40378457-40378940,
chr21-40379609-40389339,
chr21-40389621-40390661,
chr21-40394331-40395000,
chr21-40396632-40396776,
chr21-40397820-40397885,
chr21-41425596-41431302,
chr21-41431562-41433383,
chr21-41433595-41438072,
chr21-41438421-41440223,
chr21-41440635-41442106,
chr21-41442477-41454571,
-
Co-expression with cohesin genes Rho = 0.1727
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.786
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.905
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: TAMR-MCF7,K1,hTERT-HME1,H1-Mesendoderm,Olfactory,Hepatocyte-H9,MCF-7,GM12891,SARS-Cov2-olfactory,MSiPS,K-562,A-549,CyT49-pancreatic,HFFc6,HeLa-S3,LNCaP,SU-DHL-2,H9-hESC,KU-19-19,iPSC,ARPE-19,Hep-G2,HT-1197,Kelly,H1-hESC,HCC1599,Motor-Neuron,MSLCL,HUES64,SU-DHL-4,NPC-H9,CyT49-endoderm,RT-112,Jurkat,CyT49-Gut,CC-2551,HFF-hTERT
- Related loop:
chr21:38850000-38875000~~chr21:39850000-39875000,
chr21:39500000-39525000~~chr21:39850000-39875000,
chr21:39500000-39525000~~chr21:39900000-39925000,
chr21:39500000-39525000~~chr21:39925000-39950000,
chr21:39517315-39519547~~chr21:39910639-39912376,
chr21:39600000-39625000~~chr21:39850000-39875000,
chr21:39600000-39625000~~chr21:39900000-39925000,
chr21:39750000-39775000~~chr21:39900000-39925000,
chr21:39775000-39800000~~chr21:39900000-39925000,
chr21:39787215-39789565~~chr21:39910588-39912275,
chr21:39787253-39789571~~chr21:39866317-39868146,
chr21:39787253-39789571~~chr21:39910500-39912317,
chr21:39787296-39789560~~chr21:39910501-39912411,
chr21:39787332-39789505~~chr21:39910608-39912279,
chr21:39787705-39789776~~chr21:39910608-39912422,
chr21:39850000-39875000~~chr21:40050000-40075000,
chr21:39850000-39875000~~chr21:40100000-40125000,
chr21:39850000-39875000~~chr21:40125000-40150000,
chr21:39850000-39875000~~chr21:40275000-40300000,
chr21:39850000-39875000~~chr21:40375000-40400000,
chr21:39866128-39868467~~chr21:40119863-40122093,
chr21:39866153-39868505~~chr21:40120196-40122032,
chr21:39866192-39868418~~chr21:40119606-40122062,
chr21:39866204-39868182~~chr21:40119842-40122098,
chr21:39866213-39868462~~chr21:40120304-40121958,
chr21:39866223-39868177~~chr21:40120108-40122096,
chr21:39866253-39868184~~chr21:40120212-40121973,
chr21:39866275-39868439~~chr21:40119552-40122087,
chr21:39866285-39868187~~chr21:40120420-40122028,
chr21:39866287-39868162~~chr21:40120151-40122075,
chr21:39866296-39868156~~chr21:40119861-40122095,
chr21:39866307-39868195~~chr21:40120272-40122048,
chr21:39866353-39868186~~chr21:40120101-40122033,
chr21:39866375-39868193~~chr21:40120236-40122026,
chr21:39866435-39868216~~chr21:40120098-40121959,
chr21:39866538-39868625~~chr21:40120093-40122096,
chr21:39866598-39868148~~chr21:40120301-40121901,
chr21:39866650-39867964~~chr21:40120464-40121810,
chr21:39866655-39868186~~chr21:40120401-40121860,
chr21:39866691-39868175~~chr21:40120100-40122051,
chr21:39866701-39868153~~chr21:40120452-40121717,
chr21:39866710-39868154~~chr21:40120460-40121701,
chr21:39866742-39867981~~chr21:40120389-40121831,
chr21:39880996-39882805~~chr21:40119552-40122087,
chr21:39881013-39882847~~chr21:40119863-40122093,
chr21:39900000-39925000~~chr21:40100000-40125000,
chr21:39900000-39925000~~chr21:40375000-40400000,
chr21:39900000-39925000~~chr21:41425000-41450000,
chr21:39907747-39909282~~chr21:40119552-40122087,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQWD8ZYD, 4DNFIQYQWPF5, 4DNFI3CFMRID, ENCSR662QKG, 4DNFIDJ2JZ7Q, 4DNFIMROE6N4, GSE118716, 4DNFIE8E4ANZ, ENCSR499RVD, ENCSR794RDS, GSE108787, 4DNFI5SUHCGZ, GSE120294, ENCSR361AYD, ENCSR146FPM, GSE103148, 4DNFI7H4II2V, 4DNFIMEG1QIC, 4DNFIEYQ5ZIR, 4DNFI6EIFUZI, 4DNFIF2D3TL9, 4DNFIREVU1Z5, ENCSR113OIR, 4DNFIRKGMZRQ, GSE99541, ENCSR381DCY, GSE155380, 4DNFIJWBWE41, 4DNFIV239W4L, GSE97394, ENCSR452NHL, 4DNFIIMZB6Y9, ENCSR128RPG, GSE52457, ENCSR550JLK, ENCSR658RQQ, 4DNFIM2BMJ33, ENCSR299VMZ, ENCSR314HAC, Direct, 4DNFI6XD6JAQ, 4DNFIALNLR78, 4DNFIX7H3CE2, ENCSR386KHY, 4DNFIXWCLD4M, 4DNFIYDBBSE3, GSE116872, 4DNFIEJEFCAM, ENCSR228TUX, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, ENCSR778FXH, ENCSR255XYX, ENCSR404HWQ, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFIVJ3IIQL, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, 4DNFIFLJLIS5, 4DNFINEQY95T, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIQ2687RT, ENCSR094EIC, GSE105028, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
-
Involved cell types for DEG evidence: MCF-7,Cortical-non-neuronal
- Cohesin-DEGs, number of studies: 2
- Cohesin-DEGs, study: GSE177045,GSE150117
- Cohesin-DEGs, subunit: Rad21,CdLS