Deatailed information for gene ENSG00000183778
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00015566
- Gene Symbol: B3GALT5
- Ensembl ID: ENSG00000183778
-
Gene locus: chr21:39556441-39673137
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-38375250-38375602,
chr21-38376290-38378168,
chr21-38379785-38381250,
chr21-38383484-38384452,
chr21-38384798-38385015,
chr21-38387044-38387525,
chr21-38388662-38389604,
chr21-38390009-38390598,
chr21-38394330-38394741,
chr21-38524820-38525118,
chr21-38525327-38525704,
chr21-38528423-38528734,
chr21-38531264-38531985,
chr21-38544663-38545173,
chr21-38548479-38549133,
chr21-38628419-38628858,
chr21-38631075-38632314,
chr21-38636057-38637522,
chr21-38638948-38639389,
chr21-38639807-38640047,
chr21-38644766-38647197,
chr21-38649184-38649471,
chr21-38800466-38816528,
chr21-38816889-38818881,
chr21-38819201-38823342,
chr21-38823665-38827360,
chr21-38849471-38854263,
chr21-38856453-38857719,
chr21-38858525-38859524,
chr21-38859766-38860539,
chr21-38861132-38861513,
chr21-38862000-38863279,
chr21-38864066-38864405,
chr21-38867234-38867512,
chr21-38869262-38870389,
chr21-38872690-38873110,
chr21-38873491-38873832,
chr21-38874324-38875151,
chr21-39173429-39176751,
chr21-39178845-39179222,
chr21-39180628-39180930,
chr21-39181962-39185522,
chr21-39189884-39190456,
chr21-39203404-39203730,
chr21-39204248-39204463,
chr21-39205366-39206009,
chr21-39208500-39209259,
chr21-39214963-39215242,
chr21-39215761-39216148,
chr21-39219118-39219418,
chr21-39221650-39221894,
chr21-39224700-39225233,
chr21-39227967-39228342,
chr21-39230638-39230782,
chr21-39233710-39233982,
chr21-39235801-39236518,
chr21-39244018-39244348,
chr21-39246748-39247115,
chr21-39249901-39249966,
chr21-39301995-39302301,
chr21-39303859-39304491,
chr21-39305444-39305836,
chr21-39306051-39306835,
chr21-39308133-39308430,
chr21-39308844-39309885,
chr21-39311213-39311463,
chr21-39311834-39323454,
chr21-39323856-39324540,
chr21-39377536-39378376,
chr21-39378615-39382320,
chr21-39383016-39384062,
chr21-39384730-39386685,
chr21-39386888-39390967,
chr21-39395561-39395853,
chr21-39396172-39397021,
chr21-39398076-39398420,
chr21-39398702-39399019,
chr21-39502548-39502970,
chr21-39507373-39507834,
chr21-39509959-39510524,
chr21-39511165-39511517,
chr21-39514883-39522284,
chr21-39522520-39523070,
chr21-39523279-39525034,
chr21-39525261-39526244,
chr21-39526693-39532966,
chr21-39537514-39538074,
chr21-39538672-39539034,
chr21-39540003-39540686,
chr21-39555185-39555620,
chr21-39556165-39556637,
chr21-39562346-39563725,
chr21-39564249-39564742,
chr21-39565337-39565914,
chr21-39568241-39568686,
chr21-39570435-39570749,
chr21-39573222-39573683,
chr21-39578776-39580507,
chr21-39580999-39581836,
chr21-39583774-39584406,
chr21-39587741-39588079,
chr21-39594445-39594997,
chr21-39597648-39597957,
chr21-39598387-39599633,
chr21-39601006-39602588,
chr21-39604265-39605410,
chr21-39607665-39608007,
chr21-39608787-39609235,
chr21-39609628-39615120,
chr21-39616321-39616816,
chr21-39625225-39625791,
chr21-39629704-39632293,
chr21-39632853-39634794,
chr21-39636297-39636947,
chr21-39637455-39637794,
chr21-39638015-39640435,
chr21-39641876-39642112,
chr21-39642413-39642648,
chr21-39643132-39643834,
chr21-39644110-39644390,
chr21-39647406-39650769,
chr21-39652021-39652489,
chr21-39655291-39655839,
chr21-39656185-39657598,
chr21-39657848-39658299,
chr21-39660012-39662667,
chr21-39663746-39664966,
chr21-39666204-39668198,
chr21-39668545-39670696,
chr21-39673143-39674204,
chr21-39674626-39675258,
chr21-39675580-39677043,
chr21-39699714-39700227,
chr21-39701576-39703321,
chr21-39704596-39707757,
chr21-39709616-39710268,
chr21-39710803-39711977,
chr21-39712178-39719074,
chr21-39720460-39720773,
chr21-39721276-39722005,
chr21-39723416-39724008,
chr21-39750744-39751143,
chr21-39762944-39764842,
chr21-39765586-39765815,
chr21-39850419-39852964,
chr21-39853210-39853546,
chr21-39854320-39855059,
chr21-39855289-39856318,
chr21-39863160-39864324,
chr21-39864542-39868722,
chr21-39869137-39870155,
chr21-39903482-39903887,
chr21-39908275-39908862,
chr21-39909863-39913124,
chr21-39917286-39917553,
chr21-39919712-39920331,
chr21-39920803-39921032,
chr21-39924824-39925293,
chr21-39954668-39954951,
chr21-39968090-39968362,
chr21-39969684-39969938,
chr21-39973743-39973852,
chr21-39974569-39975202,
chr21-40049939-40050260,
chr21-40050498-40050756,
chr21-40053259-40055664,
chr21-40057804-40058353,
chr21-40059857-40060679,
chr21-40065862-40066154,
chr21-40070140-40071348,
chr21-40072339-40072617,
chr21-40074363-40075414,
chr21-40078619-40079012,
chr21-40079661-40079963,
chr21-40081725-40082141,
chr21-40084460-40084601,
chr21-40089448-40090020,
chr21-40099908-40100097,
chr21-40109484-40110216,
chr21-40116723-40123569,
chr21-40932779-40933193,
chr21-40936639-40937196,
chr21-40947904-40948058,
chr21-41007428-41007579,
chr21-41010992-41011299,
chr21-41012053-41012703,
chr21-41016650-41016843,
chr21-41017268-41017593,
chr21-41023102-41023234,
chr21-41023461-41025283,
chr21-41075452-41076905,
chr21-41085108-41085434,
chr21-41089578-41089986,
chr21-41091092-41091871,
chr21-41425596-41431302,
chr21-41431562-41433383,
chr21-41433595-41438072,
chr21-41438421-41440223,
chr21-41440635-41442106,
chr21-41442477-41454571,
chr21-41649662-41650037,
chr21-41650707-41652356,
chr21-41653070-41654701,
chr21-41656820-41657981,
chr21-41658412-41661789,
chr21-41662180-41667516,
chr21-41667934-41670919,
chr21-41671179-41674646,
-
Co-expression with cohesin genes Rho = 0.0244
FDR = 0.0015
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.731
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.911
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,TAMR-MCF7,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,MCF-7,HEK293T,K-562,HFFc6,HeLa-S3,H1-Trophectoderm,H9-hESC,Liver,H1-hESC,Motor-Neuron,BMEC,Left-Ventricle,HFF-hTERT,MCF7-FASR
- Related loop:
chr21:35775000-35800000~~chr21:39600000-39625000,
chr21:38375000-38400000~~chr21:39600000-39625000,
chr21:38525000-38550000~~chr21:39600000-39625000,
chr21:38625000-38650000~~chr21:39600000-39625000,
chr21:38800000-38825000~~chr21:39600000-39625000,
chr21:38850000-38875000~~chr21:39600000-39625000,
chr21:39175000-39200000~~chr21:39625000-39650000,
chr21:39175000-39200000~~chr21:39650000-39675000,
chr21:39200000-39225000~~chr21:39600000-39625000,
chr21:39225000-39250000~~chr21:39600000-39625000,
chr21:39300000-39325000~~chr21:39600000-39625000,
chr21:39375000-39400000~~chr21:39625000-39650000,
chr21:39500000-39525000~~chr21:39600000-39625000,
chr21:39500000-39525000~~chr21:39675000-39700000,
chr21:39517354-39519438~~chr21:39629845-39631913,
chr21:39525000-39550000~~chr21:39625000-39650000,
chr21:39550000-39575000~~chr21:39700000-39725000,
chr21:39600000-39625000~~chr21:39700000-39725000,
chr21:39600000-39625000~~chr21:39850000-39875000,
chr21:39600000-39625000~~chr21:39900000-39925000,
chr21:39600000-39625000~~chr21:39950000-39975000,
chr21:39600000-39625000~~chr21:40050000-40075000,
chr21:39600000-39625000~~chr21:40075000-40100000,
chr21:39600000-39625000~~chr21:40100000-40125000,
chr21:39600000-39625000~~chr21:41000000-41025000,
chr21:39600000-39625000~~chr21:41075000-41100000,
chr21:39600000-39625000~~chr21:41425000-41450000,
chr21:39625000-39650000~~chr21:41650000-41675000,
chr21:39625000-39650000~~chr21:42975000-43000000,
chr21:39633375-39634630~~chr21:39715081-39716789,
chr21:39650000-39675000~~chr21:39750000-39775000,
chr21:39650000-39675000~~chr21:40925000-40950000,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFI8649RQJ, 4DNFI3CFMRID, 4DNFIWZEN3FF, GSE43070, 4DNFIDJ2JZ7Q, GSE118716, 4DNFIMROE6N4, 4DNFIE8E4ANZ, GSE108787, 4DNFIB7QTIMH, 4DNFIBN9K4V9, 4DNFI5SUHCGZ, ENCSR794RDS, GSE120294, 4DNFIW8TIFI5, 4DNFIBM714BP, 4DNFIV239W4L, GSE52457, 4DNFIM2BMJ33, Direct, 4DNFI6XD6JAQ, 4DNFIXWCLD4M, 4DNFIZF1KI43, GSE44267, ENCSR991JXX, 4DNFIPAF4PYT, 4DNFIQVMVRP6, ENCSR255XYX, 4DNFIVJ3IIQL, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, 4DNFIFLJLIS5, GSE105028, 4DNFIDBIEXI7, GSE58752, ENCSR507AHE, 4DNFII84FBKM
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: HCT116-mAID,SLK,HPC,P3HR-1,U2OS,NUGC-3
- Cohesin-DEGs, number of studies: 7
- Cohesin-DEGs, study: GSE137253,GSE140651,GSE119828,GSE138937,GSE106886,GSE89799
- Cohesin-DEGs, subunit: SMC1,Rad21,NIPBL,CdLS