Deatailed information for gene ENSG00000185437
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00015966
- Gene Symbol: SH3BGR
- Ensembl ID: ENSG00000185437
-
Gene locus: chr21:39445854-39515506
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs
- Regulatory cohesin (double-evidenced):
chr21-38503073-38508323,
chr21-38524820-38525118,
chr21-38525327-38525704,
chr21-38528423-38528734,
chr21-38531264-38531985,
chr21-38544663-38545173,
chr21-38548479-38549133,
chr21-38800466-38816528,
chr21-38816889-38818881,
chr21-38819201-38823342,
chr21-38823665-38827360,
chr21-38999239-39001723,
chr21-39002157-39005860,
chr21-39006216-39008144,
chr21-39009600-39010167,
chr21-39010386-39017610,
chr21-39018454-39019370,
chr21-39019594-39020196,
chr21-39020597-39024249,
chr21-39024973-39026738,
chr21-39153009-39153827,
chr21-39173429-39176751,
chr21-39178845-39179222,
chr21-39180628-39180930,
chr21-39181962-39185522,
chr21-39189884-39190456,
chr21-39203404-39203730,
chr21-39204248-39204463,
chr21-39205366-39206009,
chr21-39208500-39209259,
chr21-39214963-39215242,
chr21-39215761-39216148,
chr21-39219118-39219418,
chr21-39221650-39221894,
chr21-39224700-39225233,
chr21-39227967-39228342,
chr21-39230638-39230782,
chr21-39233710-39233982,
chr21-39235801-39236518,
chr21-39244018-39244348,
chr21-39246748-39247115,
chr21-39249901-39249966,
chr21-39301995-39302301,
chr21-39303859-39304491,
chr21-39305444-39305836,
chr21-39306051-39306835,
chr21-39308133-39308430,
chr21-39308844-39309885,
chr21-39311213-39311463,
chr21-39311834-39323454,
chr21-39323856-39324540,
chr21-39326856-39327201,
chr21-39328143-39328508,
chr21-39329775-39330179,
chr21-39330451-39330860,
chr21-39332176-39332684,
chr21-39333291-39334572,
chr21-39335104-39335948,
chr21-39336590-39337662,
chr21-39338003-39338994,
chr21-39339920-39340238,
chr21-39342069-39342466,
chr21-39343271-39343467,
chr21-39343962-39344240,
chr21-39344676-39351972,
chr21-39440305-39444075,
chr21-39444581-39446444,
chr21-39447001-39447710,
chr21-39451104-39454021,
chr21-39455324-39455823,
chr21-39456702-39457849,
chr21-39461514-39462016,
chr21-39479158-39479493,
chr21-39482674-39482951,
chr21-39483873-39484360,
chr21-39485690-39486006,
chr21-39489307-39489579,
chr21-39493014-39493430,
chr21-39496169-39496513,
chr21-39496791-39497328,
chr21-39502548-39502970,
chr21-39507373-39507834,
chr21-39509959-39510524,
chr21-39511165-39511517,
chr21-39514883-39522284,
chr21-39601006-39602588,
chr21-39604265-39605410,
chr21-39607665-39608007,
chr21-39608787-39609235,
chr21-39609628-39615120,
chr21-39616321-39616816,
chr21-39629704-39632293,
chr21-39674626-39675258,
chr21-39675580-39677043,
chr21-39679749-39679955,
chr21-39681185-39681596,
chr21-39681815-39682299,
chr21-39690435-39690841,
chr21-39696739-39697109,
chr21-39697570-39697887,
chr21-39699714-39700227,
chr21-39701576-39703321,
chr21-39704596-39707757,
chr21-39709616-39710268,
chr21-39710803-39711977,
chr21-39712178-39719074,
chr21-39720460-39720773,
chr21-39721276-39722005,
chr21-39723416-39724008,
chr21-39725082-39727756,
chr21-39776876-39777010,
chr21-39787003-39790494,
chr21-39791207-39791882,
chr21-39796085-39796993,
chr21-39850419-39852964,
chr21-39853210-39853546,
chr21-39854320-39855059,
chr21-39855289-39856318,
chr21-39863160-39864324,
chr21-39864542-39868722,
chr21-39869137-39870155,
chr21-39903482-39903887,
chr21-39908275-39908862,
chr21-39909863-39913124,
chr21-39917286-39917553,
chr21-39919712-39920331,
chr21-39920803-39921032,
chr21-39924824-39925293,
chr21-39925600-39925902,
chr21-39927541-39927780,
chr21-39938129-39938456,
chr21-39939493-39939866,
chr21-40028089-40028833,
chr21-40033120-40033946,
chr21-40042249-40045555,
chr21-40047322-40047633,
chr21-40049939-40050260,
chr21-40050498-40050756,
chr21-40053259-40055664,
chr21-40057804-40058353,
chr21-40059857-40060679,
chr21-40065862-40066154,
chr21-40070140-40071348,
chr21-40072339-40072617,
chr21-40074363-40075414,
chr21-40099908-40100097,
chr21-40109484-40110216,
chr21-40116723-40123569,
chr21-40127723-40128008,
chr21-40133778-40134486,
chr21-40137553-40137697,
chr21-40138649-40139119,
chr21-40139730-40140015,
chr21-40140942-40147745,
chr21-40149386-40149804,
chr21-40353436-40353749,
chr21-40354530-40355470,
chr21-40356792-40357001,
chr21-40367620-40368318,
chr21-40369294-40369560,
chr21-40371268-40371644,
chr21-40373645-40374855,
chr21-41075452-41076905,
chr21-41085108-41085434,
chr21-41089578-41089986,
chr21-41091092-41091871,
-
Co-expression with cohesin genes Rho = 0.1211
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.574
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.888
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: IMR-90,TAMR-MCF7,MB157,DU145,Right-Ventricle,Keratinocytes192627,Aorta,GM12892,K1,Small-intestine,hTERT-HME1,Spleen,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,Pancreas,K-562,Naive-hESC,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,Primed-hESC,NCI-H1437,iPSC,Liver,ARPE-19,HCT-116,Germinal-Center-B,OCI-AML-3,Hep-G2,REC-1,HT-1197,Kelly,H1-hESC,HCC1599,GM19238,HT-1376,Lung,Motor-Neuron,MSLCL,NaiveB,U-937,Bladder,BMEC,HUES64,SU-DHL-4,CyT49-hESC,H1-NPC,HUVEC,HL-60,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Left-Ventricle,KBM-7,Jurkat,CC-2551,CyT49-Gut,HAP1,HFF-hTERT,MCF7-FASR
- Related loop:
chr21:38504739-38507562~~chr21:39440834-39442538,
chr21:38525000-38550000~~chr21:39450000-39475000,
chr21:38800000-38825000~~chr21:39425000-39450000,
chr21:39000000-39025000~~chr21:39425000-39450000,
chr21:39152734-39154644~~chr21:39445170-39446634,
chr21:39175000-39200000~~chr21:39425000-39450000,
chr21:39200000-39225000~~chr21:39425000-39450000,
chr21:39225000-39250000~~chr21:39425000-39450000,
chr21:39300000-39325000~~chr21:39425000-39450000,
chr21:39325000-39350000~~chr21:39425000-39450000,
chr21:39500000-39525000~~chr21:39600000-39625000,
chr21:39500000-39525000~~chr21:39675000-39700000,
chr21:39500000-39525000~~chr21:39700000-39725000,
chr21:39500000-39525000~~chr21:39775000-39800000,
chr21:39500000-39525000~~chr21:39850000-39875000,
chr21:39500000-39525000~~chr21:39900000-39925000,
chr21:39500000-39525000~~chr21:39925000-39950000,
chr21:39500000-39525000~~chr21:40025000-40050000,
chr21:39500000-39525000~~chr21:40050000-40075000,
chr21:39500000-39525000~~chr21:40100000-40125000,
chr21:39500000-39525000~~chr21:40125000-40150000,
chr21:39500000-39525000~~chr21:40350000-40375000,
chr21:39500000-39525000~~chr21:41075000-41100000,
chr21:39517168-39519542~~chr21:39705393-39707110,
chr21:39517168-39519542~~chr21:39715040-39717158,
chr21:39517168-39519542~~chr21:39725249-39727184,
chr21:39517259-39519458~~chr21:39714980-39716790,
chr21:39517259-39519458~~chr21:40120108-40122096,
chr21:39517261-39519776~~chr21:39714731-39716796,
chr21:39517288-39519777~~chr21:39715026-39717283,
chr21:39517297-39519497~~chr21:39714676-39716787,
chr21:39517303-39519751~~chr21:39705185-39706929,
chr21:39517303-39519751~~chr21:39712480-39713816,
chr21:39517303-39519751~~chr21:39715020-39717112,
chr21:39517303-39519751~~chr21:39787215-39789565,
chr21:39517308-39519721~~chr21:39714941-39716803,
chr21:39517315-39519547~~chr21:39714729-39716798,
chr21:39517315-39519547~~chr21:39910639-39912376,
chr21:39517315-39519547~~chr21:40120304-40121958,
chr21:39517322-39519410~~chr21:39715065-39716809,
chr21:39517329-39519377~~chr21:39715066-39716784,
chr21:39517336-39519705~~chr21:39715042-39717340,
chr21:39517343-39519431~~chr21:39715064-39716775,
chr21:39517353-39519456~~chr21:39715029-39716810,
chr21:39517354-39519438~~chr21:39629845-39631913,
chr21:39517354-39519438~~chr21:39705387-39706980,
chr21:39517354-39519438~~chr21:39712470-39713909,
chr21:39517354-39519438~~chr21:39715117-39716791,
chr21:39517358-39519642~~chr21:39705371-39706965,
chr21:39517358-39519642~~chr21:39714870-39717016,
chr21:39517360-39519534~~chr21:39705354-39706952,
chr21:39517360-39519534~~chr21:39712511-39713822,
chr21:39517360-39519534~~chr21:39715036-39716800,
chr21:39517368-39519427~~chr21:39715102-39716748,
chr21:39517369-39519405~~chr21:39715081-39716789,
chr21:39517370-39519432~~chr21:39715121-39716751,
chr21:39517370-39519511~~chr21:39715052-39716779,
chr21:39517372-39519496~~chr21:39715100-39716804,
chr21:39517377-39519678~~chr21:39715115-39716829,
chr21:39517379-39519777~~chr21:39714973-39716797,
chr21:39517380-39519751~~chr21:39714950-39717021,
chr21:39517407-39519894~~chr21:39705344-39706807,
chr21:39517407-39519894~~chr21:39715098-39716781,
chr21:39517409-39519453~~chr21:39715079-39716803,
chr21:39517410-39519337~~chr21:39715310-39716764,
chr21:39517417-39519653~~chr21:39715029-39716795,
chr21:39517439-39519408~~chr21:39715248-39716850,
chr21:39517449-39519764~~chr21:39714705-39716820,
chr21:39517449-39519764~~chr21:39725321-39727028,
chr21:39517500-39519305~~chr21:39715098-39716750,
chr21:39517500-39519881~~chr21:39715027-39716807,
chr21:39517539-39519419~~chr21:39714972-39716820,
chr21:39517541-39519337~~chr21:39715220-39716785,
chr21:39517544-39519746~~chr21:39705156-39706958,
chr21:39517544-39519746~~chr21:39715029-39716799,
chr21:39517545-39519545~~chr21:39715058-39716803,
chr21:39517560-39519419~~chr21:39715031-39716746,
chr21:39517570-39519399~~chr21:39715260-39716808,
chr21:39517570-39519399~~chr21:40120443-40121742,
chr21:39517583-39519436~~chr21:39715151-39716788,
chr21:39517618-39519383~~chr21:39715097-39716777,
chr21:39517656-39519379~~chr21:39715099-39716759,
chr21:39517703-39519567~~chr21:39715099-39716856,
chr21:39517712-39519561~~chr21:39715048-39716830,
chr21:39517734-39519372~~chr21:39715080-39716802,
chr21:39517800-39519427~~chr21:39715053-39716761,
chr21:39517814-39519374~~chr21:39715017-39716720,
chr21:39517826-39519509~~chr21:39714989-39716693,
chr21:39517837-39519461~~chr21:39715046-39716689,
chr21:39517839-39519351~~chr21:39714993-39716666,
chr21:39517856-39519435~~chr21:39714989-39716725,
chr21:39517859-39519254~~chr21:39715322-39716629,
chr21:39517864-39519219~~chr21:39715357-39716651,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, 4DNFIHMCILEN, GSE43070, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, ENCSR361AYD, 4DNFIDSWKFF5, GSE103148, 4DNFI7H4II2V, 4DNFIZ4F74QR, ENCSR350NJV, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFI9VXTBE2, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, GSE99541, ENCSR668RDP, 4DNFIS3DIH4V, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFI8Y9SRP2, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, GSE87112, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, GSE126792, ENCSR146FPM, 4DNFIOX3BGNE, GSE69643, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, 4DNFIBT4EAKN, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIH7TH4MF, 4DNFIT96Z365, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIR8OU6QJ, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, 4DNFIPV5KFMK, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIFHU75I5, 4DNFIYD8LO9Z, ENCSR444BAR, ENCSR123UVP, 4DNFIL9M97T2, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIJ7OAIFQ, 4DNFIM2BMJ33, GSE165038, 4DNFIALNLR78, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, ENCSR255XYX, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, ENCSR094EIC, GSE58752, ENCSR507AHE, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFIILDWK8M, 4DNFIP25GZGA, 4DNFI6EIFUZI, 4DNFIBCIA62Q, 4DNFII6AN691, GSE111537, GSE131580, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, 4DNFIOUSETUP, ENCSR752QCX, ENCSR128RPG, 4DNFISTWNV9C, 4DNFI6JJQKFJ, ENCSR228TUX, 4DNFIZF1KI43, 4DNFI8JFOAJT, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: K-562,SLK,P3HR-1
- Cohesin-DEGs, number of studies: 5
- Cohesin-DEGs, study: GSE140651,GSE138937,GSE131448
- Cohesin-DEGs, subunit: SMC1,Rad21,SA2