Deatailed information for gene ENSG00000205581
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00020201
- Gene Symbol: HMGN1
- Ensembl ID: ENSG00000205581
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Gene locus: chr21:39342314-39349344
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-38800466-38816528,
chr21-38816889-38818881,
chr21-38819201-38823342,
chr21-38823665-38827360,
chr21-39173429-39176751,
chr21-39178845-39179222,
chr21-39180628-39180930,
chr21-39181962-39185522,
chr21-39189884-39190456,
chr21-39311834-39323454,
chr21-39336590-39337662,
chr21-39338003-39338994,
chr21-39339920-39340238,
chr21-39342069-39342466,
chr21-39343271-39343467,
chr21-39343962-39344240,
chr21-39344676-39351972,
chr21-39354073-39354700,
chr21-39386888-39390967,
chr21-39425591-39426058,
chr21-39427352-39427664,
chr21-39430503-39430780,
chr21-39431574-39431827,
chr21-39435612-39435881,
chr21-39436505-39436763,
chr21-39440305-39444075,
chr21-39444581-39446444,
chr21-39447001-39447710,
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Co-expression with cohesin genes Rho = 0.5849
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.287
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.763
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: MCF-7,NCI-H1437,GM12878,Skin-Fibroblast,Hep-G2,HT-1376,H1-hESC,HAP1,SU-DHL-4
- Related loop:
chr21:38800000-38825000~~chr21:39325000-39350000,
chr21:39175000-39200000~~chr21:39350000-39375000,
chr21:39313200-39315343~~chr21:39347346-39350688,
chr21:39313201-39315232~~chr21:39347651-39350715,
chr21:39313213-39315341~~chr21:39347106-39349452,
chr21:39313217-39315223~~chr21:39347655-39350638,
chr21:39313225-39315438~~chr21:39347557-39350333,
chr21:39320997-39322719~~chr21:39347655-39350638,
chr21:39325000-39350000~~chr21:39425000-39450000,
chr21:39335976-39337473~~chr21:39387323-39389534,
chr21:39336013-39337477~~chr21:39387504-39389563,
chr21:39347365-39350526~~chr21:39387267-39389644,
chr21:39347651-39350709~~chr21:39387578-39389687,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFI3A3VYWU, ENCSR732QOH, ENCSR255XYX, ENCSR658RQQ, GSE95015, Direct, 4DNFI5CGQ46V, ENCSR933UZH, ENCSR833CMG, 4DNFIBN9K4V9, ENCSR981FNA, ENCSR146FPM, ENCSR587DSF
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: SLK,P3HR-1,K-562,CMK,U2OS,HeLa-S3
- Cohesin-DEGs, number of studies: 7
- Cohesin-DEGs, study: GSE140651,GSE154086,GSE131448,GSE138937,GSE89799,GSE130558
- Cohesin-DEGs, subunit: SA2,WAPL,CTCF,SMC1,Rad21