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Basic information

CohesinDB ID: CDBG00052293

Gene Symbol: APP-DT

Ensembl ID: ENSG00000273492

Gene locus: chr21:26170880-26217368 Strand: +

Gene type: lncRNA

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): False

All evidenced type: Interaction

Regulatory cohesin (double-evidenced):

Co-expression with cohesin genes Rho = -0.0406 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.738
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): nan
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: IMR-90,MB157,DU145,Keratinocytes192627,Aorta,GM12892,K1,Spleen,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,Pancreas,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,H9-hESC,KU-19-19,NCI-H460,iPSC,Liver,REC-1,Hep-G2,HT-1197,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,NaiveB,BMEC,HUES64,SU-DHL-4,HUVEC,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Left-Ventricle,CC-2551,HFF-hTERT,HAP1

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: GSE95015, GSE43070, 4DNFIDJ2JZ7Q, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, 4DNFIZ4F74QR, 4DNFI7H4II2V, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFI9VXTBE2, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR527RXH, GSE105028, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, GSE87112, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, ENCSR499RVD, 4DNFIB7QTIMH, 4DNFIBXWIH8J, 4DNFIJWBWE41, 4DNFICSTCJQZ, GSE155380, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, 4DNFI9815EEJ, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, 4DNFIPV5KFMK, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIYD8LO9Z, 4DNFIL9M97T2, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIM2BMJ33, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, GSE48592, ENCSR255XYX, ENCSR404HWQ, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, ENCSR933UZH, ENCSR094EIC, GSE58752, ENCSR507AHE, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR489OCU, 4DNFI6EIFUZI, ENCSR866FWQ, 4DNFII6AN691, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, ENCSR752QCX, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, ENCSR228TUX, 4DNFIOCW5AEM, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, 4DNFI5LCW273, 4DNFII84FBKM

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: False

Involved cell types for DEG evidence:

Cohesin-DEGs, number of studies: 0

Cohesin-DEGs, study: .

Cohesin-DEGs, subunit: .

Tools:

Assay

refGene

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APP-DT gene locus

APP-DT related cohesin sites

APP-DT related cohesin loop

Deatailed information for gene ENSG00000273492

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