Deatailed information for gene ENSG00000273590
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00052339
- Gene Symbol: SMIM11B
- Ensembl ID: ENSG00000273590
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Gene locus: chr21:7748898-7777853
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): False
- All evidenced type: Interaction
- Regulatory cohesin (double-evidenced):
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Co-expression with cohesin genes Rho = 0.1123
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): -0.000
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): nan
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: iPSC,GM12878,CyT49-endoderm,HCT-116,IMR-90,K-562,H1-hESC,CyT49-Gut,HAP1,CyT49-pancreatic,HFFc6,HeLa-S3,H9-hESC,CyT49-hESC
- Related loop:
chr21:7750000-7775000~~chr21:33875000-33900000,
chr21:7750000-7775000~~chr21:33900000-33925000,
chr21:7750000-7775000~~chr21:34225000-34250000,
chr21:7750000-7775000~~chr21:34325000-34350000,
chr21:7750000-7775000~~chr21:34350000-34375000,
chr21:7750000-7775000~~chr21:34600000-34625000,
chr21:7750000-7775000~~chr21:34625000-34650000,
- Cohesin-loop type: HiC,Direct
- Cohesin-loop study:
4DNFIQYQWPF5, 4DNFIMROE6N4, 4DNFITUOMFUQ, 4DNFI5SUHCGZ, 4DNFIEYQ5ZIR, 4DNFII6AN691, 4DNFIKYXMF1E, 4DNFIYD8LO9Z, 4DNFIJWBWE41, 4DNFICEGAHRC, 4DNFIIMZB6Y9, 4DNFI1E6NJQJ, Direct, 4DNFIYDBBSE3, 4DNFI1UEG1HD, 4DNFIEJEFCAM, 4DNFI9815EEJ, 4DNFI5LCW273, 4DNFI2J1ODWB, 4DNFIJ8JKKWJ, 4DNFIP71EWXC, 4DNFIFLJLIS5, 4DNFILIM6FDL, 4DNFIDZT7PR8, 4DNFINEQY95T, 4DNFIQ2687RT, 4DNFIH7TH4MF, 4DNFIVSCH2CH
- Cohesin-loop subunit: Other
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
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Involved cell types for DEG evidence: MCF-7
- Cohesin-DEGs, number of studies: 1
- Cohesin-DEGs, study: GSE177045
- Cohesin-DEGs, subunit: Rad21