Deatailed information for gene ENSG00000275895

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  • Basic information
  • CohesinDB ID: CDBG00053494
  • Gene Symbol: U2AF1L5
  • Ensembl ID: ENSG00000275895
  • Gene locus: chr21:6484623-6499256 Strand: -
  • Gene type: protein_coding
  • Double-evidenced cohesin related CRMs
  • Whether cohesin-related CRMs (double-evidenced): True
  • All evidenced type: Interaction,DEGs,
  • Regulatory cohesin (double-evidenced): chr21-6481133-6481536, chr21-6483752-6484339, chr21-6486893-6487171, chr21-6495944-6496328, chr21-6498283-6500376, chr21-6500611-6504404,
  • Co-expression with cohesin genes Rho = 0.2319 FDR = 0.0000
    (Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
  • Tissue specificity
  • Gene expression across tissues (TPM):
  • Tissue specificity of gene (Gini-coefficient): 0.314
    0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
  • Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.739
    0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
  • Cohesin-loop evidence
  • Whether has cohesin-loop: True
  • Involved cell types for loop evidence: SARS-Cov2-olfactory,GM12878,HCT-116,Hep-G2,IMR-90,K-562,KBM-7,H1-hESC,CC-2551,HFF-hTERT,HAP1,HFFc6,H9-hESC
  • Related loop: chr21:6475000-6500000~~chr21:42875000-42900000, chr21:6475000-6500000~~chr21:42900000-42925000, chr21:6475000-6500000~~chr21:42925000-42950000, chr21:6475000-6500000~~chr21:43075000-43100000, chr21:6500000-6525000~~chr21:43625000-43650000,
  • Cohesin-loop type: HiC,Direct
  • Cohesin-loop study: 4DNFI8649RQJ, 4DNFIMROE6N4, 4DNFITUOMFUQ, 4DNFI5SUHCGZ, 4DNFIMEG1QIC, 4DNFII6AN691, 4DNFIYD8LO9Z, 4DNFICSTCJQZ, 4DNFIIMZB6Y9, 4DNFI1E6NJQJ, 4DNFI3A3VYWU, Direct, 4DNFI6JJQKFJ, 4DNFIK61ILGM, 4DNFIEJEFCAM, 4DNFI9ZWZ5BS, 4DNFI7XAZNNQ, 4DNFIP71EWXC, 4DNFIFLJLIS5, 4DNFILIM6FDL, 4DNFIS5F6EBL, 4DNFIH7TH4MF, 4DNFII84FBKM, 4DNFIT96Z365
  • Cohesin-loop subunit: Other
  • Cohesin-DEGs evidence
  • Whether cohesin DEGs: True
  • Involved cell types for DEG evidence: HL-60,P3HR-1,K-562,MCF-10A,U2OS,HeLa-S3
  • Cohesin-DEGs, number of studies: 6
  • Cohesin-DEGs, study: GSE140651,GSE131581,GSE154086,GSE131448,GSE89799,GSE130558
  • Cohesin-DEGs, subunit: WAPL,SMC1,Rad21,SA2
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