Deatailed information for gene ENSG00000277117

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  • Basic information
  • CohesinDB ID: CDBG00054084
  • Gene Symbol: FP565260.3
  • Ensembl ID: ENSG00000277117
  • Gene locus: chr21:5022530-5036771 Strand: +
  • Gene type: protein_coding
  • Double-evidenced cohesin related CRMs
  • Whether cohesin-related CRMs (double-evidenced): True
  • All evidenced type: Interaction,DEGs
  • Regulatory cohesin (double-evidenced): chr21-5012188-5027106, chr21-5028804-5029808, chr21-5032348-5034712, chr21-5035255-5035898, chr21-5036153-5037012, chr21-5037365-5038938, chr21-5039493-5040794, chr21-5041136-5041716,
  • Co-expression with cohesin genes Rho = 0.0401 FDR = 0.0000
    (Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
  • Tissue specificity
  • Gene expression across tissues (TPM):
  • Tissue specificity of gene (Gini-coefficient): 0.394
    0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
  • Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.850
    0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
  • Cohesin-loop evidence
  • Whether has cohesin-loop: True
  • Involved cell types for loop evidence: MCF-7,HCT-116,Hep-G2,IMR-90,TAMR-MCF7,KBM-7,Olfactory
  • Related loop: chr21:5025000-5050000~~chr21:44175000-44200000, chr21:5025000-5050000~~chr21:44225000-44250000, chr21:5025000-5050000~~chr21:44250000-44275000, chr21:5025000-5050000~~chr21:44275000-44300000, chr21:5025000-5050000~~chr21:44750000-44775000,
  • Cohesin-loop type: HiC,Direct
  • Cohesin-loop study: 4DNFI6EIFUZI, Direct, GSE118716, 4DNFIP71EWXC, 4DNFIH7TH4MF, 4DNFICSTCJQZ, 4DNFIT96Z365
  • Cohesin-loop subunit: Other
  • Cohesin-DEGs evidence
  • Whether cohesin DEGs: True
  • Involved cell types for DEG evidence: HCT116-mAID,HL-60,OCI-AML-3,P3HR-1,MCF-10A,U2OS
  • Cohesin-DEGs, number of studies: 6
  • Cohesin-DEGs, study: GSE140651,GSE111537,GSE101921,GSE131581,GSE106886,GSE89799
  • Cohesin-DEGs, subunit: CTCF,SMC1,Rad21,SA2
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