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Basic information

CohesinDB ID: CDBG00055941

Gene Symbol: GATD3B

Ensembl ID: ENSG00000280071

Gene locus: chr21:5116340-5127143 Strand: -

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction

Regulatory cohesin (double-evidenced): chr21-5110876-5111483, chr21-5112238-5119849, chr21-5120084-5126026, chr21-5126436-5129485, chr21-5129914-5131366,

Co-expression with cohesin genes Rho = 0.1809 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.144
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.538
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: IMR-90,TAMR-MCF7,Keratinocytes192627,MCF-7,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,HeLa-S3,H9-hESC,iPSC,HCT-116,Hep-G2,H1-hESC,U-937,CyT49-hESC,HL-60,RT-112,CyT49-endoderm,KBM-7,CyT49-Gut,CC-2551,HAP1,HFF-hTERT,MCF7-FASR

Cohesin-loop type: HiChIP,HiC,Direct

Cohesin-loop study: 4DNFIH2A7IKF, 4DNFIQYQWPF5, ENCSR662QKG, 4DNFIBRSIPE4, 4DNFIR8OU6QJ, 4DNFI5CGQ46V, 4DNFIMROE6N4, GSE118716, 4DNFI5SUHCGZ, ENCSR545YBD, ENCSR852KQC, 4DNFIILDWK8M, 4DNFIZ4F74QR, ENCSR410MDC, 4DNFIHKWIZ9T, 4DNFIMEG1QIC, 4DNFIEYQ5ZIR, 4DNFIXU2KPNQ, 4DNFII6AN691, 4DNFIKYXMF1E, 4DNFIYD8LO9Z, GSE131580, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR123UVP, 4DNFICEGAHRC, 4DNFIIMZB6Y9, 4DNFIL9M97T2, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFIOUSETUP, 4DNFI9YAVTI1, 4DNFISTWNV9C, 4DNFI3A3VYWU, Direct, GSE165038, 4DNFIALNLR78, 4DNFISPUVQHA, 4DNFIAS8LV1C, 4DNFIBY3UHJB, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, 4DNFIYDBBSE3, 4DNFIK61ILGM, 4DNFIYIAUEPW, 4DNFIEJEFCAM, ENCSR393LOP, 4DNFI9815EEJ, 4DNFIC3HAU11, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFI7XAZNNQ, 4DNFIJ8JKKWJ, 4DNFIP71EWXC, 4DNFIFLJLIS5, 4DNFINEQY95T, 4DNFIDZT7PR8, 4DNFIQ2687RT, 4DNFIZGCA8AH, GSE105028, 4DNFIHN2QSMX, 4DNFIH7TH4MF, 4DNFII84FBKM, 4DNFIT96Z365, 4DNFIVSCH2CH

Cohesin-loop subunit: CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: False

Involved cell types for DEG evidence: HL-60,P3HR-1

Cohesin-DEGs, number of studies: 2

Cohesin-DEGs, study: GSE140651,GSE131581

Cohesin-DEGs, subunit: SMC1,SA2

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Deatailed information for gene ENSG00000280071